Product name :EPAS1 Mutant

Catalog Number :000027A

Quantity :250ul

Price :621 Eur

Pay now with :

Supplier :ABM Goods

Alias BHLHE73, HIF2A, MOP2, PASD2
Functions Dominant negative mutant form of endothelial PAS domain protein 1 (EPAS1, also called Hif-2a). It only contains only the N-terminal 1-481aa with a D tag at C-terminal. Thus this particular EPAS1 mutant lacks the C-terminal activation domain. This mutant EPAS1 retains the ability to het-erodimerize with ARNT and to bind to the HRE, but it cannot transactivate the VEGF-A promoter.
Tags Flag
Gene Type Mutant
Titer 1x106pfu/mL
Storage DMEM with 2.5% glycerol
Caution This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Notes The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. All sales are final.

 

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