Product name :ERβ

Catalog Number :000021A

Quantity :250ul

Price :948 Eur

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Supplier :ABM Goods

Alias ESR2, ESTRB, NR3A2
Protein Type Metabolic
Protein Family Nuclear Hormone Receptor Family (NR3 Subfamily)
Functions It binds estrogens and activates expression of reporter genes containing ERE (Estrogen Response Elements) in an estrogen-dependent manner. It plays a role in tumorigenesis (lung adenocarcinoma) and modulation of the estrogen response in testis.
Cell Types Widely expressed
Protein Location Nucleus
Chromosome 14q
Protein Structure ESR2 contains 530 amino acids and has an approximate molecular weight of 59216 Da. It contains N terminal modulator domain, a central bipartite zinc finger DNA binding domain followed by a nuclear localization signal and a C terminal ligand binding domain, including a transactivation and dimerization domain.
Tags No Tags
Gene Type Wild Type
Titer 1x106pfu/mL
Storage DMEM with 2.5% glycerol
Caution This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Notes The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. All sales are final.

 

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