Product name :JNK1

Catalog Number :000085A

Quantity :250ul

Price :621 Eur

Pay now with :

Supplier :ABM Goods

Alias MAPK8, PRKM8, SAPK1
Protein Type Kinase
Protein Family MAPK Family
Functions It plays a role in the signal transduction pathway initiated by proinflammatory cytokines and UV radiation, binds to the N-terminal activation domains of c-Jun and ATF2, and phosphorylates their regulatory sites (respectively ser-63 and ser-73; thr-69 and thr-71). It also plays a key role in T cell receptor-initiated helper T-cell proliferation, apoptosis and differentiation.
Cell Types Widely expressed
Protein Location Cytoplasm and Nucleus
Chromosome 10q11.1
Protein Structure The JNK1 protein has tyrosine kinase catalytic domain and RIO-like kinase domain. Four isoforms are produced by alternative splicing, isoform1, isoform4 has 427 amino acids each, and isoform2, isoforms3 has 384 amino acids each.
Tags No Tags
Gene Type Wild Type
Titer 1x106pfu/mL
Storage DMEM with 2.5% glycerol
Caution This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Notes The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. All sales are final.

 

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