Product name :PI3Kâ„¢

Catalog Number :000036A

Quantity :250ul

Price :621 Eur

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Supplier :ABM Goods

Alias GRB1
Protein Type PI3-kinase p85 subunit alpha,Enzyme, Membrane Receptor
Functions PIK3R1 binds to activated (phosphorylated) protein-Tyr Kinases, through its SH2 domain, and acts as an adapter, mediating the association of the PI3K catalytic unit to the plasma membrane. It is necessary for the Insulin-stimulated increase in Glucose uptake and Glycogen synthesis in Insulin-sensitive tissues.
Cell Types B cell, T cell and Adipocyte
Protein Location Plasma membrane
Chromosome 5q13.1
Protein Structure PIK3R1 has three isoforms; isoform 1 contains 724 amino acids having approximate molecular weight 83.6 kDa, isoform 2 contains 454 amino acids having approximate molecular weight 55 kDa and isoform 3 contains 424 amino acids having approximate molecular weight 50 kDa. It contains an N-terminal SH3 region, 2 SH2 regions, and a region of homology to the C-terminal region of BCR (B-Cell Receptor).
Tags No Tags
Gene Type Wild Type
Titer 1x106pfu/mL
Storage DMEM with 2.5% glycerol
Caution This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Notes The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. All sales are final.

 

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000036A PI3Kâ„¢ ABM Goods 250ul 621 000036A PI3Kâ„¢ ABM Goods 250ul 621€
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