Product name :PTEN

Catalog Number :000028A

Quantity :250ul

Price :621 Eur

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Supplier :ABM Goods

Alias MMAC1, TEP1
Protein Type Phosphatase
Protein Family Non-Receptor Class of Protein-Tissue Phosphate Family
Functions It antagonizes signal transduction downstream of PI-3 Kinase by dephosphorylating phosphatidylinositol-triphosphate (PtdInsP) and suppression of cell growth through the negative regulation of cell cycle and cell survival. It modulates cell cycle progression and cell survival (blockage) through down-regulating the positive cell cycle-regulator (Cyclin-D1) by its phosphatase activity and up-regulates the negative cell cycle regulator p21 (by its lipid phosphatase activity) and is a negative regulator of cell interactions with the extracellular matrix.
Cell Types Widely expressed
Protein Location Cytoplasm
Chromosome 10q23.3
Protein Structure It contains of 403 amino acids. It is a dual specificity phosphatase containing a large region of homology with chicken tensin and auxilin, a carboxyl terminal region with PEST sequence and a PDZ binding motif.
Tags No Tags
Gene Type Wild Type
Titer 1x106pfu/mL
Storage DMEM with 2.5% glycerol
Caution This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Notes The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. All sales are final.

 

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