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Search results for: 17β-Acetyl-estradiol 3-(Tri-O-acetyl-β-D-glucuronic Acid Methyl Ester) C33H42O12 CAS: 59495-70-4

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#38423951   2024/02/29 To Up

Novel benzene sulfonamides with acetylcholinesterase and carbonic anhydrase inhibitory actions.

A series of benzene sulfonamides 15-26 were synthesized and determined for their in vitro and in silico inhibitory profiles toward acetylcholinesterase (AChE) and carbonic anhydrases (CAs). Commercially available 3,4-dimethoxytoluene was reacted with chlorosulfonic acid to furnish benzene sulfonyl chloride derivatives. The reaction of substituted benzene sulfonyl chloride with some amines also including (±)-α-amino acid methyl esters afforded a series of novel benzene sulfonamides. In this study, the enzyme inhibition abilities of these compounds were evaluated against AChE and CAs. They exhibited a highly potent inhibition ability on AChE and -CAs (K values are in the range of 28.11 ± 4.55 nM and 145.52 ± 28.68 nM for AChE, 39.20 ± 2.10 nM to 131.54 ± 12.82 nM for CA I, and 50.96 ± 9.83 nM and 147.94 ± 18.75 nM for CA II). The present newly synthesized novel benzene sulfonamides displayed efficient inhibitory profiles against AChE and CAs, and it is anticipated that they may emerge as lead molecules for some diseases including glaucoma, epilepsy, and Alzheimer's disease.
Rafika El Ati, Necla Öztaşkın, Ahmet Çağan, Akın Akıncıoğlu, Yeliz Demir, Süleyman Göksu, Rachid Touzani, İlhami Gülçin

2490 related Products with: Novel benzene sulfonamides with acetylcholinesterase and carbonic anhydrase inhibitory actions.

100ug100ug50 mg 100ul100.00 ug100 mg5ug1000 tests100uL25 g5mg100ul

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#38192601   2024/01/05 To Up

The effects of different rootstocks on aroma components, activities and genes expression of aroma-related enzymes in oriental melon fruit.

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Kedong Guo, Jiateng Zhao, Siyu Fang, Qian Zhang, Lanchun Nie, Wensheng Zhao

2434 related Products with: The effects of different rootstocks on aroma components, activities and genes expression of aroma-related enzymes in oriental melon fruit.

100 μg2 Pieces/Box300 units 5 G50 ul100 ul2 Pieces/Box

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#38104709   2023/12/15 To Up

RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-3.


A M Api, A Bartlett, D Belsito, D Botelho, M Bruze, A Bryant-Freidrich, G A Burton, M A Cancellieri, H Chon, M L Dagli, W Dekant, C Deodhar, K Farrell, A D Fryer, L Jones, K Joshi, A Lapczynski, M Lavelle, I Lee, H Moustakas, J Muldoon, T M Penning, G Ritacco, N Sadekar, I Schember, T W Schultz, F Siddiqi, I G Sipes, G Sullivan, Y Thakkar, Y Tokura

1061 related Products with: RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-3.

25 mg5 mg100 mg 100 G10 mg5 mg10 mg100 mg100 mg25 mg1 mg100 mg

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#38092293   2023/12/11 To Up

RIFM fragrance ingredient safety assessment, 3-pentenoic acid, 2-methyl-, hexyl ester, CAS Registry Number 85508-08-3.


A M Api, D Belsito, D Botelho, M Bruze, G A Burton, M A Cancellieri, H Chon, M L Dagli, W Dekant, C Deodhar, A D Fryer, L Jones, K Joshi, M Kumar, A Lapczynski, M Lavelle, I Lee, D C Liebler, H Moustakas, M Na, T M Penning, G Ritacco, J Romine, N Sadekar, T W Schultz, D Selechnik, F Siddiqi, I G Sipes, G Sullivan, Y Thakkar, Y Tokura

2100 related Products with: RIFM fragrance ingredient safety assessment, 3-pentenoic acid, 2-methyl-, hexyl ester, CAS Registry Number 85508-08-3.

100 G5 mg2 g 100 G1 mg10 mg 500 G 5 G10 mg 1 G50 mg1 g

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#38052783   2023/12/05 To Up

Electrosynthesis of buckyballs with fused-ring systems from PCBM and its analogue.

[6,6]-Phenyl-C-butyric acid methyl ester (PCBM), a star molecule in the fullerene field, has found wide applications in materials science. Herein, electrosynthesis of buckyballs with fused-ring systems has been achieved through radical α-C-H functionalization of the side-chain ester for both PCBM and its analogue, [6,6]-phenyl-C-propionic acid methyl ester (PCPM), in the presence of a trace amount of oxygen. Two classes of buckyballs with fused bi- and tricyclic carbocycles have been electrochemically synthesized. Furthermore, an unknown type of a bisfulleroid with two tethered [6,6]-open orifices can also be efficiently generated from PCPM. All three types of products have been confirmed by single-crystal X-ray crystallography. A representative intramolecularly annulated isomer of PCBM has been applied as an additive to inverted planar perovskite solar cells and boosted a significant enhancement of power conversion efficiency from 15.83% to 17.67%.
Wei-Feng Wang, Kai-Qing Liu, Chuang Niu, Yun-Shu Wang, Yang-Rong Yao, Zheng-Chun Yin, Muqing Chen, Shi-Qi Ye, Shangfeng Yang, Guan-Wu Wang

2292 related Products with: Electrosynthesis of buckyballs with fused-ring systems from PCBM and its analogue.

25 mg1 mg1000 tests100ug200ul11100 mg1000 TESTS/0.65ml10 mg100ug10 mg

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#37689382   2023/09/07 To Up

Cytotoxic triterpenoid saponins from the root of Olax subscorpioidea Oliv. (Olacaceae).

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Yemi A Adekunle, Babatunde B Samuel, Lutfun Nahar, Amos A Fatokun, Satyajit D Sarker

1384 related Products with: Cytotoxic triterpenoid saponins from the root of Olax subscorpioidea Oliv. (Olacaceae).

1 mg100.00 ul2000 IU1 kit1500 Units10400 assays

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#37364759   2023/06/24 To Up

RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-5.


A M Api, D Belsito, D Botelho, M Bruze, G A Burton, MsA Cancellieri, H Chon, M L Dagli, W Dekant, C Deodhar, A D Fryer, L Jones, K Joshi, M Kumar, A Lapczynski, M Lavelle, I Lee, D C Liebler, H Moustakas, M Na, T M Penning, G Ritacco, J Romine, N Sadekar, T W Schultz, D Selechnik, F Siddiqi, I G Sipes, G Sullivan, Y Thakkar, Y Tokura

1791 related Products with: RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-5.

100 G 1 G 5 G 25 G 5 G 5 G 100 G 1 G 25 G 1 G 5 G 5 G

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#37357143   2023/07/11 To Up

Genome Mining and Molecular Networking Guided Isolation of Antimycin Analogs with Antifeedant Activities from the Deep-Sea-Derived Streptomyces sp. NA13.

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Yan Bai, Duo Ren, Fenglin Li, Jiangchun Hu, Huaqi Pan

1014 related Products with: Genome Mining and Molecular Networking Guided Isolation of Antimycin Analogs with Antifeedant Activities from the Deep-Sea-Derived Streptomyces sp. NA13.

100 U 6 ml Ready-to-use 500 gm 100 samples1 kit1,000 tests2ug200ug10x96, 2.0ml cultures 100ul1 mg500 Units

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#37126803   2023/05/01 To Up

Effects of Pregnanolone Glutamate and Its Metabolites on GABA and NMDA Receptors and Zebrafish Behavior.

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Vera Abramova, Vanessa Leal Alvarado, Martin Hill, Tereza Smejkalova, Michal Maly, Karel Vales, Ivan Dittert, Paulina Bozikova, Bohdan Kysilov, Barbora Hrcka Krausova, Vojtech Vyklicky, Ales Balik, Klevinda Fili, Miloslav Korinek, Hana Chodounska, Eva Kudova, David Ciz, Jan Martinovic, Jiri Cerny, Petr Bartunek, Ladislav Vyklicky

1016 related Products with: Effects of Pregnanolone Glutamate and Its Metabolites on GABA and NMDA Receptors and Zebrafish Behavior.

10 mg100 mg100ug1000 200ul100 mg 25 MG100ul25 mg100.00 ul200ug

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