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Search results for: 2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-D-glucono-1,5-lactone C29H31NO6 CAS: 34051-37-1

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#38497742   2024/03/18 To Up

A Poly Aptamer Encoded DNA Nanocatcher Informs Efficient Virus Trapping.

Broad-spectrum antiviral platforms are always desired but still lack the ability to cope with the threats to global public health. Herein, we develop a poly aptamer encoded DNA nanocatcher platform that can trap entire virus particles to inhibit infection with a broad antiviral spectrum. Ultralong single-stranded DNA (ssDNA) containing repeated aptamers was synthesized as the scaffold of a nanocatcher via a biocatalytic process, wherein mineralization of magnesium pyrophosphate on the ssDNA could occur and consequently lead to the formation of nanocatcher with interfacial nanocaves decorated with virus-binding aptamers. Once the viruses were recognized by the apatmers, they would be captured and trapped in the nanocaves via multisite synergistic interactions. Meanwhile, the size of nanocatchers was optimized to prevent their cellular uptake, which further guaranteed inhibition of virus infection. By taking SARS-CoV-2 variants as a model target, we demonstrated the broad virus-trapping capability of a DNA nanocatcher in engulfing the variants and blocking the infection to host cells.
Yunhua Guo, Wenzhe Song, Yuhang Dong, Xuejun Wang, Guangjun Nie, Feng Li

1138 related Products with: A Poly Aptamer Encoded DNA Nanocatcher Informs Efficient Virus Trapping.

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#38497596   2024/03/18 To Up

An Electro-optical Kerr Device Based on 2D Boron Nitride Liquid Crystals for Solar-blind Communications.

Achieving light modulation in the spectral range of 200 - 280 nm is a prerequisite for solar-blind ultraviolet communication, where current technologies mainly based on the electro-luminescent self-modulation of the ultraviolet source. External light modulation through the electro-birefringence control of liquid crystal devices has shown success in the visible-to-infrared regions. However, the poor stability of conventional liquid crystals against ultraviolet irradiation and their weak electro-optical response make it challenging to modulate ultraviolet light. Here, we demonstrate an external ultraviolet light modulator using two-dimensional boron nitride liquid crystal. It exhibits robust ultraviolet stability and a record-high specific electro-optical Kerr coefficient of 5.1×10 m V , being three orders of magnitude higher than those of other known electro-optical media that are transparent (or potentially transparent) in the ultraviolent spectral range. The sensitive response enables us to fabricate transmissive and stable UV-C electro-optical Kerr modulators for solar-blind ultraviolet light. We also demonstrate an M-ary coding array with high transmission density for solar-blind ultraviolet communication. This article is protected by copyright. All rights reserved.
Youan Xu, Ziyang Huang, Zehao Zhang, Baofu Ding, Peixuan Li, Jiarong Liu, Yugan Hao, Lixin Dai, Hao Zhang, Caizhen Zhu, Wei Cai, Bilu Liu

1623 related Products with: An Electro-optical Kerr Device Based on 2D Boron Nitride Liquid Crystals for Solar-blind Communications.

100ul0.2 mg100.00 ug100 mg0.2 mg1100ug100ug100.00 ug10 mg96 Tests100ug

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#38497553   2024/03/18 To Up

Dual Enhancement of Phosphorescence and Circularly Polarized Luminescence through Entropically Driven Self-Assembly of a Platinum(II) Complex.

Addressing the dual enhancement of circular polarization (glum) and luminescence quantum yield (QY) in circularly polarized luminescence (CPL) systems poses a significant challenge. In this study, we present an innovative strategy utilizing the entropically driven self-assembly of amphiphilic phosphorescent platinum(II) complexes (L-Pt) with tetraethylene glycol chains, resulting in unique temperature dependencies. The entropically driven self-assembly of L-Pt leads to a synergistic improvement in phosphorescence emission efficiency (QY was amplified from 15% at 25 °C to 53% at 60 °C) and chirality, both in the ground state and the excited state (glum value has been magnified from 0.04 × 10-2 to 0.06) with increasing temperature. Notably, we observed reversible modulation of phosphorescence and chirality observed over at least 10 cycles through successive heating and cooling, highlighting the intelligent control of luminescence and chiroptical properties by regulating intermolecular interactions among neighboring L-Pt molecules. Importantly, the QY and glum of the L-Pt assembly in solid state were measured as 69% and 0.16 respectively, representing relatively high values compared to most self-assembled CPL systems. This study marks the pioneering demonstration of dual thermo-enhancement of phosphorescence and CPL and provides valuable insights into the thermal effects on high-temperature and switchable CPL materials.
Yanqing Wang, Na Li, Liangwen Chu, Zelin Hao, Junyu Chen, Jiang Huang, Junlin Yan, Hongtao Bian, Pengfei Duan, Jing Liu, Yu Fang

2837 related Products with: Dual Enhancement of Phosphorescence and Circularly Polarized Luminescence through Entropically Driven Self-Assembly of a Platinum(II) Complex.

50 ug 1 mg50 ul100ug100 50ul (1mg/ml)1,000 tests1 ml25 mg1 ml100ul

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#38497484   2024/03/18 To Up

Iron Status and Risk of Heart Disease, Stroke, and Diabetes: A Mendelian Randomization Study in European Adults.

The relevance of iron status biomarkers for coronary artery disease (CAD), heart failure (HF), ischemic stroke (IS), and type 2 diabetes (T2D) is uncertain. We compared the observational and Mendelian randomization (MR) analyses of iron status biomarkers and hemoglobin with these diseases.
Yunan Liu, Robert Clarke, Derrick A Bennett, Geng Zong, Wei Gan

1503 related Products with: Iron Status and Risk of Heart Disease, Stroke, and Diabetes: A Mendelian Randomization Study in European Adults.

50 UG 5 G100ug25 mg96 tests 5 G50 ug 5mg100ug1 g

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#38497449   2024/03/18 To Up

Flexible light-stimulated artificial synapse based on detached (In,Ga)N thin film for neuromorphic computing.

Because of wide range of applications, the flexible artificial synapse is an indispensable part for next-generation neural morphology computing. In this work, we demonstrate a flexible synaptic device based on a lift-off (In,Ga)N thin film successfully. The synaptic device can mimic the learning, forgetting, and relearning functions of biological synapses at both flat and bent states. Furthermore, the synaptic device can simulate the transition from short-term memory to long-term memory successfully under different bending conditions. With the high flexibility, the excitatory post-synaptic current of the bent device only shows a slight decrease, leading to the high stability. Based on the experimental conductance for long-term potentiation and depression, the simulated three-layer neural network can achieve a high recognition rate up to 90.2%, indicating that the system comprising of flexible synaptic devices could have a strong learning-memory capability. Therefore, this work has a great potential for the development of wearable intelligence devices and flexible neuromorphic systems.
Qianyi Zhang, Binbin Hou, Jianya Zhang, Xiushuo Gu, Yonglin Huang, Renjun Pei, Yukun Zhao

1605 related Products with: Flexible light-stimulated artificial synapse based on detached (In,Ga)N thin film for neuromorphic computing.

1 G 1 G 25 G 500 G 25 MG 1 G 5 G0.1 mg1 mg 5 G 1 G

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#38497266   2024/03/18 To Up

More than a colour; how pigment influences colourblind microbes.

Many animals have pigments when they themselves cannot see colour. Perhaps those pigments enable the animal to avoid predators, or to attract mates. Maybe even those pigmented surfaces are hosts for microbes, even when the microbes do not see colour. Do some pigments then serve as a chemical signal for a good or bad microbial substrate? Maybe pigments attract or repel various microbe types? Echinoderms serve as an important model to test the mechanisms of pigment-based microbial interactions. Echinoderms are marine benthic organisms, ranging from intertidal habitats to depths of thousands of metres and are exposed to large varieties of microbes. They are also highly pigmented, with a diverse variety of colours between and even within species. Here we focus on one type of pigment (naphthoquinones) made by polyketide synthase, modified by flavin-dependent monoxygenases, and on one type of function, microbial interaction. Recent successes in targeted gene inactivation by CRISPR/Cas9 in sea urchins supports the contention that colour is more than it seems. Here we dissect the players, and their interactions to better understand how such host factors influence a microbial colonization. This article is part of the theme issue 'Sculpting the microbiome: how host factors determine and respond to microbial colonization'.
Gary M Wessel, Lili Xing, Nathalie Oulhen

2413 related Products with: More than a colour; how pigment influences colourblind microbes.

100ug100ug Lyophilized100ug Lyophilized1 g5 G100ug Lyophilized100ug Lyophilized100.00 ug2 mL1 Set200 100ug

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#38497122   2024/03/18 To Up

Highly coordinative molecular cobalt-phthalocyanine electrocatalyst on an oxidized single-walled carbon nanotube for efficient hydrogen peroxide production.

HO production the two-electron oxygen reduction reaction (2e ORR) offers a potential alternative to the current anthraquinone method owing to its efficiency and environmental friendliness. However, it is necessary to determine the structures of electrocatalysts with cost-effectiveness and high efficiency for future industrialization demand. Herein, a supramolecular catalyst composed of cobalt-phthalocyanine on a near-monodispersed and oxidized single-walled carbon nanotube (CoPc/o-SWCNT) was synthesized a solution self-assembly method for catalyzing the 2e ORR for HO electrosynthesis. Benefiting from the enhanced intermolecular interaction by introducing oxygen functional grups on o-SWCNTs, the oxidation states of single-atom Co sites were tuned the formation of two extra Co-O bonds. Coupled with structural characterizations, density-functional theory (DFT) calculations reveal that the depressed d-band center of the Co site regulated by two axially-bridged O atoms gives rise to a suitable binding strength of oxygen intermediates (*OOH) to favor the 2e ORR. Thus, the CoPc-6wt%/o-SWCNT-2 catalyst with optimized synthetic parameters delivers competitive 2e ORR performance for HO electrosynthesis in a neutral electrolyte (pH = 7), including enhanced HO generation, satisfactory molar selectivity of ∼83-95% and long-period stability (75 h) in H-cell measurement. Moreover, it could also be boosted to show a high current of 45 mA cm, recorded turnover frequency of 25.3 ± 0.5 s and maximum HO production rate of 5.85 mol g h with a continuous HO accumulation of 1.2 wt% in a flow-cell device, which outperformed most of the reported neutral-selective nonprecious metal single-atom catalysts.
Yaoxin Li, Haoying Cheng, Meilin Wang, Jiaoxing Xu, Lunhui Guan

2984 related Products with: Highly coordinative molecular cobalt-phthalocyanine electrocatalyst on an oxidized single-walled carbon nanotube for efficient hydrogen peroxide production.

1g4 Arrays/Slide4 Arrays/Slide2 Pieces/Box4 Membranes/Box2 Pieces/Box4 Membranes/Box4 Membranes/Box4 Arrays/Slide5x10 mL25 µg4 Arrays/Slide

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