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           Search results for: 5-[4-(Aminomethyl)-3,5-dimethoxyphenoxy]pentanoic Acid Acetate C16H25NO7 CAS: 125666-67-3�   

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#28872850   2017/09/05 Save this To Up

Enhancing the Mass Spectrometry Sensitivity for Oligonucleotide Detection by Organic Vapor Assisted Electrospray.

There are two challenges in oligonucleotide detection by liquid chromatography coupled with mass spectrometry (LC-MS), the serious ion suppression effects caused by ion-pair reagents and the low detection sensitivity in positive mode MS. In this study, highly concentrated alcohol vapors were introduced into an enclosed electrospray ionization chamber, and oligonucleotides could be well detected in negative mode MS even with 100 mM triethylammonium acetate (TEAA) as an ion-pair reagent. The MS signal intensity was improved 600-fold (for standard oligonucleotide dT15) by the isopropanol vapor assisted electrospray, and effective ion-pair LC separation was feasibly coupled with high-sensitive MS detection. Then, oligonucleotides were successfully detected in positive mode MS with few adducts by propanoic acid vapor assisted electrospray. The signal intensity was enhanced more than 10-fold on average compared with adding acids into the electrospray solution. Finally, oligonucleotides and peptides or histones were simultaneously detected in MS with little interference with each other. Our strategy provides a useful alternative for investigating the biological functions of oligonucleotides.

1433 related Products with: Enhancing the Mass Spectrometry Sensitivity for Oligonucleotide Detection by Organic Vapor Assisted Electrospray.

Beta Amyloid (1 42) High Formaldehyde Detection Ki MarkerGeneTM Fluorescent RubyGlowTM Luminescent Ba Cellufine Formyl , 50 ml Cellufine Formyl Media Cellufine Formyl , 500 ml Cellufine Formyl Media Cellufine Formyl Media DAB (Post) Enhancing Sol DAB (Post) Enhancing Sol Fontana-Masson Stain Kit

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#28789688   2017/08/09 Save this To Up

An in vitro synthetic biosystem based on acetate for production of phloroglucinol.

Phloroglucinol is an important chemical, and the biosynthesis processes which can convert glucose to phloroglucinol have been established. However, due to approximate 80% of the glucose being transformed into undesirable by-products and biomass, this biosynthesis process only shows a low yield with the highest value of about 0.20 g/g. The industrial applications are usually hindered by the low current productivity and yield and also by the high costs. Generally, several different aspects limit the development of phloroglucinol biosynthesis. The yield of phloroglucinol is one of the most important parameters for its bioconversion especially from economic and ecological points of view. The in vitro biosynthesis of bio-based chemicals, is a flexible alternative with potentially high-yield to in vivo biosynthetic technology.

1760 related Products with: An in vitro synthetic biosystem based on acetate for production of phloroglucinol.

Cultrex In Vitro Angiogen Cultrex In Vitro Angiogen Rabbit Anti-FGF3 Oncogene Endothelial Tube Formatio Interleukin-34 IL34 (N-t Interleukin-34 IL34 anti ING1B antisense HIV type O envelope antig HIV 2 gp36 envelope antig HIV 1 intergase antigen. MOUSE ANTI BOVINE ROTAVIR Anti AGO2 Human, Monoclon

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#28766035   2017/08/02 Save this To Up

Valuable biochemical production in mixed culture fermentation: fundamentals and process coupling.

The mixed culture fermentation is an important environmental biotechnology that converts biodegradable organic wastes to valuable chemicals such as hydrogen, methane, acetate, ethanol, propionate, and so on. For the multistep process of hydrolysis, acidogenesis, acetogenesis/homoacetogensis, and methanogenesis, the typical metabolic reactions are firstly summarized. And then, since the final metabolites are always a mixture, the separation and purification processes are necessary to couple with anaerobic fermentation. Therefore, several typical coupling technologies including biogas upgrading, two-stage fermentation, gas stripping, membrane technology of pervaporation, membrane distillation, electrodialysis, bipolar membrane electrodialysis, and microbial fuel cells are summarized to separate the metabolites and recover energy. At last, the novel technologies such as the controlled metabolite production, medium chain carboxylic acid production, and high temperature ethanol recovery in thermophilic mixed culture fermentation are also reviewed. However, the novel concepts are still needed to meet the demands of better overall performances and lower total costs.

1425 related Products with: Valuable biochemical production in mixed culture fermentation: fundamentals and process coupling.

GLP 2 ELISA Kit, Rat Prog C Peptide ELISA Kit, Rat Incu Tissue(square vessel Incu Tissue(square vessel Incu Tissue(square vessel Breast various pathology Biocidal ZF, spray disinf Biocidal ZF, spray disinf Biocidal ZF, spray disinf Interleukin-34 IL34 (N-t Interleukin-34 IL34 anti Sterile filtered goat se

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#28737186   2017/07/24 Save this To Up

Ionic liquid [OMIm][OAc] directly inducing oxidation cleavage of the β-O-4 bond of lignin model compounds.

We explored the oxidation reactions of lignin model compounds directly induced by ionic liquids under metal-free conditions. In this work, it was found that ionic liquid 1-octyl-3-methylimidazolium acetate as a solvent could promote the aerobic oxidation of lignin model compound 2-phenoxyacetophenone (1) and the yields of phenol and benzoic acid from 1 could be as high as 96% and 86%, respectively. A possible reaction pathway was proposed based on a series of control experiments. An acetate anion from the ionic liquid attacked the hydrogen from the β-carbon thereby inducing the cleavage of the C-O bond of the aromatic ether. Furthermore, it was found that 2-(2-methoxyphenoxy)-1-phenylethanone (4) with a methoxyl group could also be transformed into aromatic products in this simple reaction system and the yields of phenol and benzoic acid from 4 could be as high as 98% and 85%, respectively. This work provides a simple way for efficient transformation of lignin model compounds.

2602 related Products with: Ionic liquid [OMIm][OAc] directly inducing oxidation cleavage of the β-O-4 bond of lignin model compounds.

NFkB p50 Blocking Peptide CCR3 Blocking Peptide;App Smad4 Blocking Peptide;Ap MMP-9 Blocking Peptide;Ap MMP-12 Blocking Peptide;A Math1 Blocking Peptide;Ap LOX-1 Blocking Peptide;Ap FOXP3 Blocking Peptide;Ap LRP-5 6 Blocking Peptide; Kallikrein 12 (KLK12) Blo MMP-12 Blocking Peptide;A Tom 40 Blocking Peptide;A

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#28709885   2017/07/15 Save this To Up

Modeling of acetate-type fermentation of sugar-containing wastewater under acidic pH conditions.

In this study, a kinetic model was developed based on Anaerobic Digestion Model No. 1 to provide insights into the directed production of acetate and methane from sugar-containing wastewater under low pH conditions. The model sufficiently described the dynamics of liquid-phase and gaseous products in an anaerobic membrane bioreactor by comprehensively considering the syntrophic bioconversion steps of sucrose hydrolysis, acidogenesis, acetogenesis and methanogenesis under acidic pH conditions. The modeling results revealed a significant pH-dependency of hydrogenotrophic methanogenesis and ethanol-producing processes that govern the sucrose fermentative pathway through changing the hydrogen yield. The reaction thermodynamics of such acetate-type fermentation were evaluated, and the implications for process optimization by adjusting the hydraulic retention time were discussed. This work sheds light on the acid-stimulated acetate-type fermentation process and may lay a foundation for optimization of resource-oriented processes for treatment of food wastewater.

2733 related Products with: Modeling of acetate-type fermentation of sugar-containing wastewater under acidic pH conditions.

Acetate Buffer Solution, Acetate Buffer Solution, Interferon-a Receptor Typ Phorbol 12 myristate 13 a Sodium Acetate (NaAc 3 M Type II 5-phosphatase ant 3mol l Sodium Acetate Buf 4-(2-Acetoxy-ethyl)phenyl 2-Acetate�-6-[(phenylme 10X PHOSPHATE BUFFERED SA Plant Sucrose Phosphate S Bovine secreted phosphopr

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#28667369   2017/07/01 Save this To Up

DFT studies of the substituent effects of dimethylamino on non-heme active oxidizing species: iron(V)-oxo species or iron(IV)-oxo acetate aminopyridine cation radical species?

Through the introduction of dimethylamino (Me2N) substituent at the pyridine ring of 2-((R)-2-[(R)-1-(pyridine-2-ylmethyl)pyrrolidin-2-yl]pyrrolidin-1-ylmethyl)pyridine (PDP) ligand, the non-heme Fe(II)((Me2N)PDP)/H2O2/AcOH catalyst system was found to exhibit significant higher catalytic activity and enantioselectivity than the non-substituent one in the asymmetric epoxidation experiments. The mechanistic origin of the remarkable substituent effects in these oxidation reactions has not been well established. To ascertain the potent oxidant and the related reaction mechanism, a detailed DFT calculation was performed. Interestingly, a novel Fe(IV)-oxo (Me2N)PDP cation radical species, [((Me2N)PDP)(+)(·)Fe(IV)(O)(OAc)](2+) ( (Me2N) 5), with about one spin spreading over the non-heme (Me2N)PDP ligand was formed via a carboxylic-acid-assisted O-O bond heterolysis, which is reminiscent of Compound I (an Fe(IV)(O)(porphyrin cation radical) species) in cytochrome P450 chemistry. (Me2N) 5 is energetically comparable with the cyclic ferric peracetate species (Me2N) 6, while in the pristine Fe(PDP) catalyst system, (H) 6 is more stable than (H) 5. Comparison of the activation energy for the ethylene epoxidation promoted by (Me2N) 5 and (Me2N) 6, (Me2N) 5 is supposed as the true oxidant triggering the epoxidation of olefins. In addition, a systematic research on the substituent effects varied from the electron-donating substituent (dMM, the substituents at sites 3, 4, and 5 of the pyridine ring: methyl, methoxyl, and methyl) to the electron-withdrawing one (CF3, 2,6-bis(trifluoromethyl)phenyl) on the electronic structure of the reaction intermediates has also been investigated. An alternative cyclic ferric peracetate complex is obtained, indicating that the substituents at the pyridine ring of PDP ligands have significant impacts on the electronic structure of the oxidants.

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ubiquinol-cytochrome c re ORC2 antibody Source Rabb TCP-1 theta antibody Sour ORP-1 antibody Source Rab beta IV Tubulin antibody oral-facial-digital syndr RAP2C, member of RAS onco MOUSE ANTI BOVINE ROTAVIR GSK3â(Phospho Ser9) Anti c Jun (Phospho Ser73) Ant Elk 1 (Phospho Ser383) An PDK1 (Phospho Ser241) Ant

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#28621138   2017/06/16 Save this To Up

Divergent Synthesis of Solanidine and 22-epi-Solanidine.

A divergent synthesis of solanidine and 22-epi-solanidine, two 25S natural steroidal alkaloids, from 25R-configured diosgenin acetate, is described. Initially, solanidine was synthesized through a series of transformations including a cascade ring-switching process of furostan-26-acid, an epimerization of C25 controlled by the conformation of six-membered lactone ring, an intramolecular Schmidt reaction, and an imine reduction/intramolecular aminolysis process. To address the epimerization issue during Schmidt reaction, an improved synthesis was developed, which also led to a synthesis of 22-epi-solanidine. In this synthesis, selective transformation of azido lactone to azido diol and amino diol was realized through a reduction relay tactic. The azido diol was transformed to solanidine via an intramolecular Schmidt reaction/N-alkylation/reduction process and to 22-epi-solanidine via an intramolecular double N-alkylation process.

1332 related Products with: Divergent Synthesis of Solanidine and 22-epi-Solanidine.

Androgen Receptor (Phosph Androgen Receptor (Phosph Rabbit Anti-Human Androge Rabbit Anti-Human Androge Androgen Receptor (Ab 650 AZD-3514 Mechanisms: Andr 17β-Acetoxy-2α-bromo-5 (5α,16β)-N-Acetyl-16-[2 (5α,16β)-N-Acetyl-16-ac 5α-N-Acetyl-2'H-androst- 5α-N-Acetyl-2'H-androst- 3-O-Acetyl 5,14-Androstad

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#28597426   2017/06/09 Save this To Up

Anti-hepatitis, antioxidant activities and bioactive compounds of Dracocephalum heterophyllum extracts.

Dracocephalum heterophyllum was a traditional Tibetan medicine possesses various pharmacological effects involved in anti-inflammatory, antibacterial activities. However, its anti-hepatitis, antioxidant activity and bioactive compounds have not been reported, the objective of this research work was to investigate the pharmacological activity and bioactive compounds of D. heterophyllum extracts.

1158 related Products with: Anti-hepatitis, antioxidant activities and bioactive compounds of Dracocephalum heterophyllum extracts.

Rabbit Anti-Human Androge Rabbit Anti-Human Androge Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H Rabbit Anti-Polyprotein(H

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#28576467   2017/06/03 Save this To Up

RIFM fragrance ingredient safety assessment, acetic acid, C7-9-branched alkyl esters, C8-rich, CAS Registry Number 108419-32-5.

The use of this material under current conditions is supported by existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental and reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, as well as environmental safety. Data show that this material is not genotoxic. Data from the suitable read across analog isoamyl acetate (CAS# 123-92-2) show that this material does not have skin sensitization potential. The reproductive and local respiratory toxicity endpoints were completed using the TTC (Threshold of Toxicological Concern) for a Cramer Class I material (0.03 mg/kg/day and 1.4 mg/day, respectively). The repeated dose and developmental endpoint was completed using data on the target material, which provided a MOE > 100. The phototoxicity/photoallergenicity endpoint was completed based on suitable UV spectra. The environmental endpoint was completed as described in the RIFM Framework.

1715 related Products with: RIFM fragrance ingredient safety assessment, acetic acid, C7-9-branched alkyl esters, C8-rich, CAS Registry Number 108419-32-5.

Indole 3 acetic acid CAS 4 Fluorocinnamic acid CAS Thiophene 2 acetic acid C 3 Chlorosalicylic acid CA Alginic acid CAS Number [ 3,4 Dihydroxyphenylacetic Indole 3 butyric acid CAS Pyridine 3 acetic acid hy 7 Hydroxycoumarin 4 aceti 2 Nitrophenylpyruvic acid Pyridine 3 acetic acid hy 2,3,4 Trifluorophenylboro

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#28574746   2017/06/02 Save this To Up

Microbial production of mevalonate by recombinant Escherichia coli using acetic acid as a carbon source.

We sought to produce mevalonate, an important organic acid, by recombinant Escherichia coli, using acetic acid, a less costly alternative feedstock, as a carbon source. In this study, the mevalonate biosynthesis pathway originating with acetate was constructed in recombinant E. coli, resulting in the production of 1.06 g L(-1) mevalonate with a productivity of 0.03 g L(-1) h(-1) in a 5-L bioreactor. The mevalonate concentration and productivity were significantly enhanced with increased cell density during 2-stage aerobic fermentation, reaching 7.85 g L(-1) and 0.13 g L(-1) h(-1), respectively. Fed-batch fermentation was further optimized under anaerobic and microaerobic conditions, and mevalonate concentrations reached 3.05 g L(-1) and 4.97 g L(-1), respectively, indicating that the oxygen supply exerts a large impact on mevalonate production from acetate. This study describes a method with high potential to produce mevalonate with the engineered E. coli strain XU143 using the less costly alternative feedstock acetate as a carbon source.

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Bone Morphogenetic Protei Fibroblast Growth Factor Fibroblast Growth Factor Growth Differentiation Fa Macrophage Colony Stimula RANK Ligand Soluble, Huma RANK Ligand Soluble, Huma Acetic Acid Solution (0. Acetic Acid Solution (0. Acetic Acid Solution (0. Acetic Acid Solution (0. Acetic Acid Solution (1%

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