Search results for: 9-[[2-(α-L-Alanyloxy)ethoxy]methyl]guanine Hydrochloride C11H17ClN6O4 CAS: 84499-63-8
#38618031 2024/01/31 To Up
Constipation anti-aging effects by dairy-based lactic acid bacteria.
Constipation, which refers to difficulties in defecation and infrequent bowel movement in emptying the gastrointestinal system that ultimately produces hardened fecal matters, is a health concern in livestock and aging animals. The present study aimed to evaluate the potential effects of dairy-isolated lactic acid bacteria (LAB) strains to alleviate constipation as an alternative therapeutic intervention for constipation treatment in the aging model. Rats were aged via daily subcutaneous injection of D-galactose (600 mg/body weight [kg]), prior to induction of constipation via oral administration of loperamide hydrochloride (5 mg/body weight [kg]). LAB strains ( USM 4189 or USM 4187) were administered daily via oral gavage (1 × 10 Log CFU/day) while the control group received sterile saline. Aged rats as shown with shorter telomere lengths exhibited increased fecal bulk and soften fecal upon administration of LAB strains amid constipation as observed using the Bristol Stool Chart, accompanied by a higher fecal moisture content as compared to the control ( < 0.05). Fecal water-soluble metabolite profiles showed a reduced concentration of threonine upon administration of LAB strains compared to the control ( < 0.05). Histopathological analysis also showed that the administration of LAB strains contributed to a higher colonic goblet cell count as compared to the control ( < 0.05). The present study illustrates the potential of dairy-sourced LAB strains as probiotics to ameliorate the adverse effect of constipation amid aging, and as a potential dietary intervention strategy for dairy foods including yogurt and cheese.Mohamad Hafis Jaafar, Pei Xu, Uma-Mageswary Mageswaran, Shandra-Devi Balasubramaniam, Maheswaran Solayappan, Jia-Jie Woon, Cindy Shuan-Ju Teh, Svetoslav Dimitrov Todorov, Yong-Ha Park, Guoxia Liu, Min-Tze Liong
2449 related Products with: Constipation anti-aging effects by dairy-based lactic acid bacteria.
100 µl100ug Lyophilized 10 UG100ug Lyophilized100ug Lyophilized100.00 ug100ug Lyophilized100ug Lyophilized100ug Lyophilized100ug Lyophilized100ug Lyophilized100ug LyophilizedRelated Pathways
#38578703 2024/04/05 To Up
-Fluorosulfonyl Guanidine: An Entry to -Guanyl Sulfamides and Sulfamates.
Here, we present the straightforward synthesis of -fluorosulfonyl guanidine () from two industrial feedstocks, guanidine hydrochloride and sulfuryl fluoride (SOF), using SuFEx chemistry. Compound exhibits excellent stability under ambient conditions and displays unique SuFEx reactivity toward amines and phenols to generate -guanyl sulfamides and sulfamates that have rarely been accessed. Notably, water serves as an effective solvent in this process. Our protocol provides a reliable pathway for the synthesis and investigation of these novel guanidine-containing molecules.Wei Wang, Jingyuan Li, Long Xu, Jiajia Dong
1954 related Products with: -Fluorosulfonyl Guanidine: An Entry to -Guanyl Sulfamides and Sulfamates.
1 module50 1 module100 ug1,000 tests1 mg1 module100 μg200ug200 ug1 moduleRelated Pathways
#38574538 2024/04/01 To Up
Highly sensitive "off-on" sensor based on MXene and magnetic microspheres for simultaneous detection of lung cancer biomarkers - Neuron specific enolase and carcinoembryonic antigen.
In this work, a highly sensitive lung cancer biomarkers detection probe was developed based on Ag and MXene co-functionalized magnetic microspheres. By using carboxyl magnetic microspheres as carrier, MXene was coated repeatedly by Poly (allylamine hydrochloride) (PAH) as interlayer adhesive, and silver particles grown on the surface of MXene in situ can efficiently improve the sensitivity of the probe. The detection of neuron specific enolase (NSE) is mainly through the formation of a specific complex between NSE antigen and antibody, and the release of antibody labeled with amino carbon quantum dots (CQDs) from the surface of Ag nanoparticles (AgNPs), so that the fluorescence is restored and "OFF-ON" is formed. The biosensor exhibits excellently wide linear range (0.0001-1500 ng/mL) and the limit of detection (LOD) is up to 0.03 pg/mL, which is superior to most tumor marker probes based on fluorescence mechanism. Furthermore, we constructed dual detection strategy for NSE and carcinoembryonic antigen (CEA) simultaneously.Chenyu Yin, Xiang Zhao, Zhizhou Liu, Le Ma, Pengyun Sun, Liang He, Huajie Huang, Pengli Bai
2579 related Products with: Highly sensitive "off-on" sensor based on MXene and magnetic microspheres for simultaneous detection of lung cancer biomarkers - Neuron specific enolase and carcinoembryonic antigen.
1 mg0.2 mg96T2 Pieces/Box96 tests4 Arrays/Slide0.1 mg2 Pieces/Box96 testsRelated Pathways
#38528777 2024/03/25 To Up
In Situ Synthesized Low-Dimensional Perovskite for >25% Efficiency Stable MA-Free Perovskite Solar Cells.
Developing an additive to effectively regulate the perovskite crystallization kinetics for the optimized optoelectronic properties of perovskite film plays a vital role in obtaining high efficiency and stable perovskite solar cells (PSCs). Herein, a new additive is designed and directly synthesized in perovskite precursor solution by utilizing an addition reaction between but-3-yn-1-amine hydrochloride (BAH) and formamidinium iodide. It is found that its product may control the intermediate precursor phase for regulating perovskite nucleation, leading to advantageous 2D perovskite to induce growth of perovskite along the preferred [001] orientation with not only released lattice strain but also strong interaction with perovskite to passivate its surface defects. By taking advantage of the above synergistic effects, the optimized PSC delivers an efficiency of 25.19% and a high open-circuit voltage (V) of 1.22 V. Additionally, the devices demonstrate good stability, remaining over 90% of their initial efficiencies under ambient atmosphere conditions for 60 days, high temperature of 85 °C for 200 h, or maximum power point tracking for 500 h.Yong Li, Yuwei Duan, Zhike Liu, Lu Yang, Hongxiang Li, Qunping Fan, Hui Zhou, Yiqiao Sun, Meizi Wu, Xiaodong Ren, Ningyi Yuan, Jianning Ding, Shaoming Yang, Shengzhong Liu
2527 related Products with: In Situ Synthesized Low-Dimensional Perovskite for >25% Efficiency Stable MA-Free Perovskite Solar Cells.
96 assays96 tests10 ug500 MGOne Vial: 5 X 10^6 Cells5 ml1 mg1x10e7 cells2 mlRelated Pathways
#37965749 2023/11/15 To Up
Atomically Precise Metal Nanocluster Photosystem: Electron Relay Boosts Photocatalytic Organic Transformation.
Atomically precise metal nanoclusters (NCs) demonstrate emerging potential as a new generation of photosensitizers in photoredox catalysis. However, metal NCs suffer from intrinsic poor instability, which leads to the loss of photosensitization effect and hampers their widespread applications in heterogeneous photocatalysis. Herein, we corroborate the design of a spatially directional charge transfer pathway over transition metal chalcogenide (TMC)-based heterostructures by way of a facile and efficient electrostatic self-assembly approach. Positively charged solid-state nonconjugated insulating polymer of poly(allylamine hydrochloride) (PAH) and negatively charged glutathione (GSH) capped metal NCs [Ag@(GSH)] as building blocks were controllably and highly ordered anchored on the TMC substrate. It was unveiled that owing to the appropriate energy level alignment and interface configuration, photogenerated electrons over metal NCs can directionally flow to the TMC substrate with the aid of PAH, which functions as an interfacial charge transfer mediator, and simultaneously holes migrate in the opposite direction, thereby collaboratively contributing to substantially boosted charge separation and prolonged charge lifetime. Benefiting from these merits, the thus self-assembled TMCs/PAH/metal NC heterostructure unfolds conspicuously enhanced photoactivity toward anaerobic selective photocatalytic reduction of nitroaromatics to amino derivatives under visible light irradiation. This work would significantly reinforce our fundamental understanding of the charge transfer characteristic of atomically precise metal NCs and the charge-withdrawing capability of solid insulating polymers for solar energy conversion.Qing Chen, Xing-Zu Ge, Linhui Yu, Fang-Xing Xiao
2054 related Products with: Atomically Precise Metal Nanocluster Photosystem: Electron Relay Boosts Photocatalytic Organic Transformation.
250 g100μg100ug100μg100ug100μg100ug100μg100μg100ug100μg96TRelated Pathways
#37866592 2023/10/20 To Up
Contamination of water, soil, and plants by micropollutants from reclaimed wastewater and sludge from a wastewater treatment plant.
Several studies have shown that plants can absorb various micropollutants. The behavior of micropollutants from wastewater treatment plant resources was comprehensively investigated in raised beds in which either a mixture of vegetables or maize was grown. The beds were either irrigated with treated wastewater or enriched with sewage sludge or composted sewage sludge. Over the year, samples of wastewater, water drained from the beds, soils and plants were analyzed. Of the seventy-five analyzed substances, fifty-four, thirty-three and twenty-seven were quantified in wastewater, sewage sludge, and composted sludge, respectively. Alarmingly, approximately 20 % of the compounds from wastewater were also detected in the solutions leached from the beds irrigated with wastewater (e.g., gabapentin, tramadol, sertraline, carbamazepine, its metabolites, and benzotriazoles). In addition, a gradual increase in the content of four substances (telmisartan, venlafaxine, carbamazepine, citalopram) was recorded in these beds. The compounds from both biosolids used for soil enrichment tended to remain in the soils (e.g., telmisartan, venlafaxine, sertraline, its metabolite, citalopram, and its metabolite). Only four compounds (sertraline and three benzotriazoles) leached from these beds. Uptake of some chemicals (e.g., gabapentin, tramadol, carbamazepine and its metabolite, and venlafaxine and its metabolite) and their accumulation in plant tissues was observed mainly in vegetables grown on beds irrigated with wastewater. However, daily consumption values for edible plant parts and individual compounds did not indicate a direct threat to human health. Results of this innovative study show possible risks associated with the use of these resources in agriculture. Of particular concern is the possible micropollutants percolation towards groundwater, including those for which high sorption and thus low mobility in the soil environment is expected, such as sertraline. Soil and crop contamination cannot be neglected either.Radka Kodešová, Helena Švecová, Aleš Klement, Miroslav Fér, Antonín Nikodem, Ganna Fedorova, Oleksandra Rieznyk, Martin Kočárek, Alina Sadchenko, Alica Chroňáková, Roman Grabic
2479 related Products with: Contamination of water, soil, and plants by micropollutants from reclaimed wastewater and sludge from a wastewater treatment plant.
100ug200 25 mg100 mg 25 MG10 mg0.1 mg100ug200ul25 mg1000 testsRelated Pathways
-
No related Items
#37802505 2023/12/07 To Up
Optimizing the Buried Interface in Flexible Perovskite Solar Cells to Achieve Over 24% Efficiency and Long-Term Stability.
The buried interface of the perovskite layer has a profound influence on its film morphology, defect formation, and aging resistance from the outset, therefore, significantly affects the film quality and device performance of derived perovskite solar cells. Especially for FAPbI , although it has excellent optoelectronic properties, the spontaneous transition from the black perovskite phase to nonperovskite phase tends to start from the buried interface at the early stage of film formation then further propagate to degrade the whole perovskite. In this work, by introducing ─NH rich proline hydrochloride (PF) with a conjugated rigid structure as a versatile medium for buried interface, it not only provides a solid α-phase FAPbI template, but also prevents the phase transition induced degradation. PF also acts as an effective interfacial stress reliever to enhance both efficiency and stability of flexible solar cells. Consequently, a champion efficiency of 24.61% (certified 23.51%) can be achieved, which is the highest efficiency among all reported values for flexible perovskite solar cells. Besides, devices demonstrate excellent shelf-life/light soaking stability (advanced level of ISOS stability protocols) and mechanical stability.Ruoyao Xu, Fang Pan, Jinyu Chen, Jingrui Li, Yingguo Yang, Yulu Sun, Xinyi Zhu, Peizhou Li, Xiangrong Cao, Jun Xi, Jie Xu, Fang Yuan, Jinfei Dai, Chuantian Zuo, Liming Ding, Hua Dong, Alex K-Y Jen, Zhaoxin Wu
2234 related Products with: Optimizing the Buried Interface in Flexible Perovskite Solar Cells to Achieve Over 24% Efficiency and Long-Term Stability.
0.1 mg 1x10e7 cells100 μg1.00 flask100 μgRelated Pathways
#37757611 2023/07/22 To Up
Blocking sphingosine 1-phosphate receptor 1 with modulators reduces immune cells infiltration and alleviates endometriosis in mice.
Do sphingosine 1-phosphate (S1P) modulators have therapeutic effects on endometriosis in mice and, if they do, which receptor is responsible for these effects?Fengrui Zhang, Mingyi Peng, Xufen Zheng, Xiaofang Wang, Xiaoxiao Liu, Chun Chen, Yuan Lu
2440 related Products with: Blocking sphingosine 1-phosphate receptor 1 with modulators reduces immune cells infiltration and alleviates endometriosis in mice.
100ug100ug100ug Lyophilized100ug100ug Lyophilized100ul100ug100ug100ug100ug Lyophilized 1 G100ugRelated Pathways
#37531764 2023/07/26 To Up
Dissipation of twelve organic micropollutants in three different soils: Effect of soil characteristics and microbial composition.
The dissipation kinetics and half-lives of selected organic micropollutants, including pharmaceuticals and others, were systematically investigated and compared among different soil types. While some pollutants (e.g., atorvastatin, valsartan, and bisphenol S) disappeared rapidly in all the tested soils, many of them (e.g., telmisartan, memantine, venlafaxine, and azithromycin) remained persistent. Irrespective of the soil characteristics, venlafaxine showed the lowest dissipation kinetics and the longest half-lives (250 to approximately 500 days) among the stable compounds. The highest first and second-order kinetics were, however, recorded for valsartan (k; 0.262 day) and atorvastatin (k; 33.8 g μg day) respectively. Nevertheless, more than 90% (i.e., DT) of all the rapidly dissipated compounds (i.e., atorvastatin, bisphenol S, and valsartan) disappeared from the tested soils within a short timescale (i.e., 5-36 days). Dissipation of pollutants that are more susceptible to microbial degradation (e.g., atorvastatin, bisphenol S, and valsartan) seems to be slower for soils possessing the lowest microbial biomass C (C) and total phospholipid fatty acids (PLFA), which also found statistically significant. Our results revealing the persistence of several organic pollutants in agricultural soils, which might impact the quality of these soils, the groundwater, and eventually on the related biota, is of high environmental significance.Sunil Paul M Menacherry, Radka Kodešová, Ganna Fedorova, Alina Sadchenko, Martin Kočárek, Aleš Klement, Miroslav Fér, Antonín Nikodem, Alica Chroňáková, Roman Grabic
2620 related Products with: Dissipation of twelve organic micropollutants in three different soils: Effect of soil characteristics and microbial composition.
1 mg100 μg10 ug5 mg25 mg 5 G5mgRelated Pathways
#37502349 2023/01/14 To Up
A Case of Cerebral Hyperperfusion Syndrome during Treatment of Transient Cerebral Vasospasm Following Carotid Artery Stenting.
We report a case in which transient cerebral vasospasm after carotid artery stenting (CAS) was effectively treated using arterial and intravenous infusion of fasudil hydrochloride, but cerebral hyperperfusion syndrome (CHS) developed during subsequent treatment.Motoshige Yamashina, Yohei Sato, Mariko Noda, Mayu Sasakawa, Thiparpa Thamamongood, Akihiro Hashizume, Takahiro Ogishima, Masashi Tamaki
1437 related Products with: A Case of Cerebral Hyperperfusion Syndrome during Treatment of Transient Cerebral Vasospasm Following Carotid Artery Stenting.
100 ulRelated Pathways
-
No related Items
Contact Us:
Belgium
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45 Fax 0032 16 50 90 45
[email protected]
France
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50 Fax 01 43 25 01 60
[email protected]
Germany
GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Tel 0241 40 08 90 86 Fax 0241 55 91 05 36
[email protected]
United Kingdom
GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
[email protected]
Also in
Luxembourg +35220880274
Schweiz Züri +41435006251
Danmark +4569918806
Österreich +43720880899
Česká republika Praha +420246019719
Ireland Dublin +35316526556
Norge Oslo +4721031366
Finland Helsset +358942419041
Sverige Stockholm +46852503438
Ελλάς Αθήνα +302111768494
Magyarország Budapest +3619980547
Poland
GENTAUR Poland Sp. z o.o.
ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
Tel 058 710 33 44
Fax 058 710 33 48
[email protected]
skype gentaurpoland
Nederland
GENTAUR Nederland BV
Kuiper 1
5521 DG Eersel Nederland
Tel 0208-080893 Fax 0497-517897
[email protected]
Italy
GENTAUR SRL
IVA IT03841300167
Piazza Giacomo Matteotti, 6, 24122 Bergamo
Tel 02 36 00 65 93 Fax 02 36 00 65 94
[email protected]
Spain
GENTAUR Spain
Tel 0911876558
[email protected]
Bulgaria
GENTAUR Bulgaria
53 Iskar Str. 1191 Kokalyane, Sofia
Sofia 1000
Tel 0035924682280
Fax 0035929830072
[email protected]