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A fully coupled framework for in silico investigation of in-stent restenosis.

Finite element analysis (FEA) can be implemented along with Agent-based model (ABM) to investigate the biomechanical and mechanobiological mechanisms of pathophysiological processes. However, traditional ABM-FEA approaches are often partially coupled and lack the feedback responses from biological analysis. To overcome this problem, a fully coupled ABM-FEA framework is developed in this paper by linking the macro-scale and cell-scale modules bi-directionally. Numerical studies of the in-stent restenosis process are conducted using the proposed approach and comparisons are made between the two types of frameworks. A reduction in lumen loss rate, which is possibly caused by the time-varying stresses, is observed in the fully coupled simulations. The re-endothelialisation process is also simulated under different frameworks and the simulation results show strong inhibition of endothelial cells to vascular restenosis. The proposed method is proved to be effective to explain the biomechanical-mechanobiological coupling characteristics of the restenosis problem and can be utilized for stent design and optimization.

1014 related Products with: A fully coupled framework for in silico investigation of in-stent restenosis.

Breast invasive ductal ca Multiple lung carcinoma ( FIV Core Ag, recombinant EpiQuik Histone Methyltra Inhibitory Monoclonal ant Rabbit Anti-Influenza B Rabbit Anti-Phospho-INPPL ATM Kinase Inhibitor, KU- Influenza A H5N1 (Avian) (1S,3S)-1-(1,3-Benzodioxo Lung cancer and adjacent AKT1 (dn) Inducible

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Quantitation and distribution of metallic elements in sequestra of medication-related osteonecrosis of jaw (MRONJ) using inductively coupled plasma atomic emission spectroscopy and synchrotron radiation X-ray fluorescence analysis.

Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse effect of antiresorptive agents like bisphosphonates. Abnormal concentrations of various trace metallic elements contained in bone minerals have been associated with MRONJ. In this study, we focused on trace metallic elements contained in the MRONJ sequestrum; their content and distribution were compared to those in osteomyelitis and non-inflammatory bones using inductively coupled plasma atomic emission spectroscopy (ICP-AES) and synchrotron radiation X-ray fluorescence analysis (SR-XRF). On ICP-AES analyses, various trace elements (Co, Cr, Cu, Fe, K, Mg, Ni, Sb, Ti, V, Pb) were significantly more in MRONJ sequestra than non-inflammatory bones. The Cu content was significantly higher in MRONJ sequestra than osteomyelitis and non-inflammatory bones. The Cu content in MRONJ sequestra was high even after decalcification. Additionally, Cu was distributed along the trabecular structures in decalcified MRONJ specimens, as observed using SR-XRF analysis. Therefore, this study was indicative of the characteristic behavior of Cu in MRONJ.

1055 related Products with: Quantitation and distribution of metallic elements in sequestra of medication-related osteonecrosis of jaw (MRONJ) using inductively coupled plasma atomic emission spectroscopy and synchrotron radiation X-ray fluorescence analysis.

Ofloxacin CAS Number [824 Bovine Androstenedione,AS Androstenedione-19 Antibo Amplite™ Calcium Quanti Androgen Receptor (5α)-2'H-Androst-2-eno[3 Rabbit Plasma US Origin I Anti Androgen Receptor pr (3β)-Androsta-5,16-diene Rabbit Plasma US Origin I Androgen Receptor , Mouse (5α)-Androstane-3,11,17-

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Custom-designed orthopedic plates using semantic parameters and template.

To quickly construct and conveniently modify the ideal orthopedic plates for individuals, a novel approach for designing the customized orthopedic plates is put forward based on bone template and plate semantic parameters, thus avoiding the need for the detailed geometric operations and the design of orthopedic plates from scratch each time. Firstly, an average bone model (ABM) is created from the existing bone models, among which each bone has an equal contribution to the ABM, and then the template, which contains region of interest (ROI) and segmentation regions, is constructed based on the ABM. Secondly, attached on the template ROI, the abutted surface feature of an orthopedic plate is designed including definition of characteristic points and configuration of semantic parameters, with a directed graph proposed to define the constraint relationship between semantic parameters. Lastly, the custom-designed plate for the target bone can be adaptively generated with a group of new semantic parameter values which are obtained through the mapping from the template to the target bone model. This plate can be easily extended to suit the bones of the same type for individuals by just editing semantic parameters. This method supports modification for a custom-designed plate with semantic parameters, consequently promoting the quality and efficiency of orthopedic plate design. Graphical abstract.

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Custom Human CD97 ELISA E Custom Human VEGF-D ELISA Custom Rat CINC-2 alpha E Andrographolide CAS Numbe Screen Quest™ Colorimet Custom Human DcR3 ELISA E Custom Mouse BTC ELISA EL Custom Cotton Rat IFN-gam Androst-4-ene-3,6,17-trio Protein G Coated 96 well Custom Human FAP ELISA EL Custom Mouse Chordin ELIS

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[Exposure Dose Reduction for Radiologists with Combination of Angular Beam Modulation and Radiation Protection Drape in CT Fluoroscopy: A Phantom Study].

To assess the dose reduction of radiologists by using angular beam modulation (ABM) and radiation protection drape during computed tomography (CT) fluoroscopy.

2388 related Products with: [Exposure Dose Reduction for Radiologists with Combination of Angular Beam Modulation and Radiation Protection Drape in CT Fluoroscopy: A Phantom Study].

GSK3B & CTNNB1 Protein Pr FGFR1 & CTNNB1 Protein Pr CDK6 & CTNNB1 Protein Pro Goat Anti-Human CTLA + CT STAT5B & CTLA4 Protein Pr Infiltrating duct carcino ACTN4 & CTNNB1 Protein Pr NFKB1 & CTNNB1 Protein Pr DKK1 & CTNNB1 Protein Pro CD86 & CTLA4 Protein Prot MYLK & CTTN Protein Prote ACTN1 & CTNNA1 Protein Pr

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Prosthetic mesh placement for the prevention of parastomal herniation.

Parastomal herniation is a common problem following formation of a stoma after both elective and emergency abdominal surgery. Symptomatic hernias give rise to a significant amount of patient morbidity, and in some cases mortality, and therefore may necessitate surgical treatment to repair the hernial defect and/or re-site the stoma. In an effort to reduce this complication, recent research has focused on the application of a synthetic or biological mesh, inserted during stoma formation to help strengthen the abdominal wall.

1702 related Products with: Prosthetic mesh placement for the prevention of parastomal herniation.

Rabbit anti PKC theta (Ab 6-Amino-1-benzyl-5-(N-for Mouse PAI-1 (wild type la Anti-BMP-1 (Bone Morphoge 5-Acetylamino-6-formylami Rat PAI-1 (wild type acti 5 L F-Solv 100% Formaldeh 4 Formylimidazole (4(5) I Tissue array of ovarian g Mouse Anti-Ca19.9 Sialyl Formylmethyl triphenylpho FDA Standard Frozen Tissu

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Isolated forearm technique: a meta-analysis of connected consciousness during different general anaesthesia regimens.

General anaesthesia should prevent patients from experiencing surgery, defined as connected consciousness. The isolated forearm technique (IFT) is the current gold standard for connected consciousness monitoring. We evaluated the efficacy of different anaesthesia regimens in preventing IFT responses.

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Analysis Tool for AAH-CYT Rabbit Anti-IEX1 Differen Analysis Tool for AAM-ISO Analysis Tool for AAH-GF- Goat Anti- T-cell differe Analysis Tool for AAH-PRT Resorufin 7 O methyl ethe Analysis Tool for AAM-CYT Colon well differentiated Analysis Tool for AAM-CYT FitAmp General DNA Quanti Analysis Tool for AAR-CYT

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Deformation and dynamic response of abdominal aortic aneurysm sealing.

Endovascular sealing is a new technique for the repair of abdominal aortic aneurysms. Commercially available in Europe since 2013, it takes a revolutionary approach to aneurysm repair through minimally invasive techniques. Although aneurysm sealing may be thought as more stable than conventional endovascular stent graft repairs, post-implantation movement of the endoprosthesis has been described, potentially leading to late complications. The paper presents for the first time a model, which explains the nature of forces, in static and dynamic regimes, acting on sealed abdominal aortic aneurysms, with references to real case studies. It is shown that elastic deformation of the aorta and of the endoprosthesis induced by static forces and vibrations during daily activities can potentially promote undesired movements of the endovascular sealing structure.

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CAR,CAR,Constitutive acti Androstenedione 19 Recombinant Human Androge Anti BRF1(Butyrate respon Anti Abdominal B Monoclon Androgen Receptor Antibod Androst-16-en-3-ol C19H30 Androsta-3,5,16-trien-17- Primary antibody Caspase CAR,Car,Constitutive andr Androgen Receptor (Phosph ∆2-Androstene-1α,17β-

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Investigation of 2 Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes.


2572 related Products with: Investigation of 2 Prototypes of Novel Noncontact Technologies for Automated Real-Time Capture of Incremental Drug Administration Data From Syringes.

Ofloxacin CAS Number [824 Staphylococcus Aureus Rea Avian Influenza virus H5N Dengue Virus General type HSV I & II Real Time PCR Uterine Cervix Cancer of Antibodies Purification CryoSolve- Box Kit (25 si Bordetella Pertussis Real Norwalk virus Real Time R Chikungunya Virus Real Ti Avidin Columns Adar's (

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Biomimetic Artificial Basilar Membranes for Next-Generation Cochlear Implants.

Patients with sensorineural hearing loss can recover their hearing using a cochlear implant (CI). However, there is a need to develop next-generation CIs to overcome the limitations of conventional CIs caused by extracorporeal devices. Recently, artificial basilar membranes (ABMs) are actively studied for next-generation CIs. The ABM is an acoustic transducer that mimics the mechanical frequency selectivity of the BM and acoustic-to-electrical energy conversion of hair cells. This paper presents recent progress in biomimetic ABMs. First, the characteristics of frequency selectivity of the ABMs by the trapezoidal membrane and beam array are addressed. Second, to reflect the latest research of energy conversion technologies, ABMs using various piezoelectric materials and triboelectric-based ABMs are discussed. Third, in vivo evaluations of the ABMs in animal models are discussed according to the target position for implantation. Finally, future perspectives of ABM studies for the development of practical hearing devices are discussed.

2396 related Products with: Biomimetic Artificial Basilar Membranes for Next-Generation Cochlear Implants.

Cytokine (Human) Antibody Formalin Solution (20%) 3-Formylindol-1-yl-acetic IpPore track etched membr Cytokine (Mouse) Antibody Acetyl 2-[(2-Formamide-1, 4 Formylphenylboronic aci IpPore track etched membr Inflammation (Human) Anti rac-N-Benzyl-N-[2-hydroxy IpPore track etched membr Bone Morphogenetic Protei

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Bioprocess scale-up/down as integrative enabling technology: from fluid mechanics to systems biology and beyond.

Efficient optimization of microbial processes is a critical issue for achieving a number of sustainable development goals, considering the impact of microbial biotechnology in agrofood, environment, biopharmaceutical and chemical industries. Many of these applications require scale-up after proof of concept. However, the behaviour of microbial systems remains unpredictable (at least partially) when shifting from laboratory-scale to industrial conditions. The need for robust microbial systems is thus highly needed in this context, as well as a better understanding of the interactions between fluid mechanics and cell physiology. For that purpose, a full scale-up/down computational framework is already available. This framework links computational fluid dynamics (CFD), metabolic flux analysis and agent-based modelling (ABM) for a better understanding of the cell lifelines in a heterogeneous environment. Ultimately, this framework can be used for the design of scale-down simulators and/or metabolically engineered cells able to cope with environmental fluctuations typically found in large-scale bioreactors. However, this framework still needs some refinements, such as a better integration of gas-liquid flows in CFD, and taking into account intrinsic biological noise in ABM.

1200 related Products with: Bioprocess scale-up/down as integrative enabling technology: from fluid mechanics to systems biology and beyond.

Total Antioxidant Capacit  EpiQuik Total Histone H Total Human tPA Functiona TOXOPLASMA GONDII Culture Mouse Vitronectin Total A Glutathione (GSH GSSG Tot  EpiQuik Total Histone H N,N,N Trimethyl 4 (6 phen Cell Meter™ Fluorimetri Mouse Plasminogen Total A Total Rat tPA Antigen Ass anti 5Methylcytosine anti

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