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           Search results for: Biological Fluids: Pooled Normal Human Urine   

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#23775902   2015/06/03 Save this To Up

Increased bisecting N-acetylglucosamine and decreased branched chain glycans of N-linked glycoproteins in expressed prostatic secretions associated with prostate cancer progression.

Using prostatic fluids rich in glycoproteins like prostate-specific antigen and prostatic acid phosphatase (PAP), the goal of this study was to identify the structural types and relative abundance of glycans associated with prostate cancer status for subsequent use in emerging MS-based glycopeptide analysis platforms.

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Prostate cancer, PIN (pro Prostate disease spectrum Rectum disease spectrum ( Kidney disease spectrum ( Prostate cancer, adjacent Brain disease spectrum (b Colon disease spectrum (c Ovarian disease spectrum Ovary disease spectrum (o Pancreatic disease spectr Prostate cancer tissue ar Prostate cancer tissue ar

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#7794038   1995/07/27 Save this To Up

Identification and functional importance of plasma kallikrein in the synovial fluids of patients with rheumatoid, psoriatic, and osteoarthritis.

To determine and identify, unequivocally, if plasma kallikrein (PK) is present in the synovial fluid of patients with rheumatoid (RA), psoriatic (PA) and osteo (OA) arthritis, and to consider its functional importance in the inflamed joint.

2202 related Products with: Identification and functional importance of plasma kallikrein in the synovial fluids of patients with rheumatoid, psoriatic, and osteoarthritis.

Bovine Androstenedione,AS Androgen Receptor (Phosph Androgen Receptor (Phosph Rabbit Anti-Human Androge Rabbit Anti-Human Androge Androgen Receptor (Ab 650 Lipoproteins, Human Plasm AZD-3514 Mechanisms: Andr 17β-Acetoxy-2α-bromo-5 (5α,16β)-N-Acetyl-16-[2 (5α,16β)-N-Acetyl-16-ac 5α-N-Acetyl-2'H-androst-

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#2604047   1990/02/02 Save this To Up

Analysis of a glucose-containing tetrasaccharide by high-performance liquid affinity chromatography.

In the present work we have explored conditions for using a pulsed amperometric detector for on-line analysis of oligosaccharides eluted from a high-performance liquid affinity chromatography column. A monoclonal antibody that specifically binds a glucose-containing oligosaccharide is coupled to a SelectiSphere-10-activated tresyl column. The system is eluted isocratically and easily detects 10 ng of the oligosaccharide with a linear response up to 250 ng. Analysis of both serum and urine samples from normal individuals and patients with acute pancreatitis gives a single retarded peak with a retention time identical to that of authentic (Glc)4. Retarded material pooled from several analyses of urine was positively identified as (Glc)4 by GC-MS analysis. As this method requires little cleanup and no chemical derivitization of the sample and is performed rapidly (less than 20 min) at sensitivities of at least 10 micrograms/liter in biological fluids, it represents a substantial improvement over previous GC-MS, radioimmunoassay, and enzyme-linked immunoadsorbent assay methods used to determine (Glc)4.

1610 related Products with: Analysis of a glucose-containing tetrasaccharide by high-performance liquid affinity chromatography.

Native full length fibron Rabbit Anti Human PAI1 Af Rabbit Anti Human tPA Aff Rabbit Anti Human uPA Aff Rabbit Anti Human uPA Aff Rabbit Anti Mouse PAI1 Af Rabbit Anti Mouse PAI1 Af Rabbit Anti Mouse Plasmin Rabbit Anti Mouse uPA Aff Rabbit Anti Mouse uPA Aff Cytokeratin, High Molecu Cytokeratin, High Molecu

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#3422430   1988/03/03 Save this To Up

Isomeric prostaglandin F2 compounds arising from prostaglandin D2: a family of icosanoids produced in vivo in humans.

Prostaglandin (PG) D2 has been shown to be transformed by human 11-ketoreductase to 9 alpha,11 beta-PGF2, a biologically active metabolite that is produced in vivo. During the course of developing a mass spectrometric assay for 9 alpha,11 beta-PGF2, several compounds with characteristics similar to PGF2 were detected in both plasma and urine of normal humans by selected ion monitoring. Analysis of pooled plasma obtained from patients with mastocytosis during severe episodes of systemic mast cell activation associated with the release of markedly increased quantities of PGD2 was revealing in that all of these compounds were present in approximately 800-fold greater abundance compared to levels found in normal plasma, suggesting that these compounds arose from PGD2 metabolism. Complete electron impact mass spectra were obtained of these compounds in both plasma and urine; these spectra established that they were all isometric forms of PGF2. Approximately 16 isomeric PGF2 compounds were identified. Treatment with butylboronic acid indicated that the C-9 and C-11 hydroxyls were trans in approximately one-third of the compounds and cis in approximately two-thirds. Preliminary experiments suggest that PGD2 is a very labile compound in vivo and undergoes extensive isomerization, after which reduction by 11-ketoreductase yields a family of more stable isomeric PGF2 compounds. Elucidating the profile of biological activity of these compounds and their mechanism of formation will contribute importantly to our understanding of the biological consequences of PGD2 release in vivo. These results also bring into question the reliability of assays for PGF2 alpha and its metabolites in human biological fluids as a specific index of endogenous PGF2 alpha biosynthesis, as these assays may also measure in part isomeric PGF2 compounds arising from PGD2 metabolism.

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Goat Anti-Human EP4 prost anti HSV (II) gB IgG1 (mo anti HCMV IE pp65 IgG1 (m anti HCMV gB IgG1 (monocl Caspase-Family Inhibitor Caspase-Family Inhibitor Goat Anti-Human F2R PAR1, prostaglandin F2 receptor Directed In Vivo Angiogen ABT-263 Mechanisms: Bcl-2 ABT-737 Mechanisms: Bcl-2 EGF Phospho-Specific Arra

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#6658442   1984/02/23 Save this To Up

Determination of chromium in human milk, serum and urine by electrothermal atomic absorption spectrometry without preliminary ashing.

In the present study a Perkin-Elmer 5000 atomic absorption spectrometer equipped with a tungsten--iodide lamp for improved background correction at the 357.9 nm chromium absorption line and an HGA 500 graphite furnace were employed for the direct determination of chromium in human serum, milk and urine. The method of standard additions was used: 0.25-0.75 ng Cr was added to 1 ml samples. Except for urine samples, a dilution of 1 + 1 to 1 + 2 with H2O was necessary in order to obtain correct calibration curves. The average concentration of chromium in all the samples of normal subjects was less than 0.5 ng Cr ml-1. The day-to-day variation for all of the pooled samples was around 10% (relative standard deviation). For urine, the accuracy of the method was tested by comparing the results of another laboratory for the same two round robin samples. Excellent agreement was found between the present method and those of the other laboratory that had used isotope dilution--mass spectrometry and continuum source wavelength modulated echelle--atomic absorption spectrometry to define the chromium concentration in the samples. The detection limit of the method, 0.05 ng Cr ml-1 for urine and serum and 0.1 ng Cr ml-1 for human milk, was sufficient for the biological fluids analyzed. The method was employed for the determination of chromium in 24-h urine samples of maturity onset diabetics supplemented with 20 or 200 micrograms Cr3+ d-1 for six weeks. It was shown that the 24-h urinary chromium excretion accurately indicates the daily dietary chromium intake of these patients.

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Human interleukin 2(IL-2) Human Kininogen (HMW) ELI Human Hemopexin ELISA Kit Sterile filtered human se Sterile filtered human se Sterile filtered goat se Sterile filtered goat se Sterile filtered mouse s Sterile filtered rat ser Anti AGO2 Human, Monoclon Anti AGO2 Human, Monoclon CELLKINES Natural Human I

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