Search results for: Custom Human HSP70 ELISA ELISA
#30865286 // Save this To Up
Heat shock protein 70 dampens the inflammatory response of human PDL cells to mechanical loading in vitro.Previously, we demonstrated an inflammatory response of human PDL (hPDL) cells to mechanical loading. The cellular reaction was dampened by heat pre-treatment suggesting a protective role for heat shock proteins (HSP) during stress-induced ischemia. Here we explored if HSP70, which has already been documented in the pressure zone of tooth movement, might be regulatorily involved in the attenuation of the inflammatory response.
2138 related Products with: Heat shock protein 70 dampens the inflammatory response of human PDL cells to mechanical loading in vitro.Heat Shock 70kDa Protein Heat Shock Protein 20, hu Heat Shock Protein 70, hu Human Macrophage Inflamma Human Gro g Macrophage In Rabbit Anti-Human Toll In Human Macrophage Inflamma Human Macrophage Inflamma Heat Shock Protein 27, hu Heat Shock Protein 70, hu Human Macrophage Inflamma Human Dnak (HSP70) His ta
#30527115 // Save this To Up
Hydrogen peroxide-mediated oxidative stress induces inflammasome activation in term human placental explants.The placenta is a multifunctional organ that can suffer with imbalances between pro- and antioxidant molecules, contributing for inflammatory imbalance. The inflammation generated by oxidative stress may induce inflammasome activation, an essential complex for pro-inflammatory cytokine production.
1067 related Products with: Hydrogen peroxide-mediated oxidative stress induces inflammasome activation in term human placental explants.Goat Anti-Human MRP8 ABCC Transcription factors: O Goat Anti-Human HMGB3 HMG Goat Anti-Human F2R PAR1, Goat Anti-Human Bruno-lik Goat Anti-Human CACNB4 (i Amplite™ Fluorimetric H Goat Anti-Human ABCE1 RNA Goat Anti-Human KCNJ11 KA Goat Anti-Human GLuR5 GRI Goat Anti-Human DGAT2, (i Goat Anti-Human NAT10 hAL
#29901164 // Save this To Up
Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling.Curcumin has been revealed to inhibit liver cancer, however, no studies have reported that the mechanism of curcumin's action on liver cancer is related to damage-associated molecular pattern (DAMP) molecules heat shock protein 70 (HSP70) and the toll-like receptor 4 (TLR4) signaling. This study aimed to investigate whether the activation of TLR4 signaling by HSP70 could be inhibited by curcumin, thus investigating the possible mechanism of curcumin in the inhibition of liver cancer. Western blotting was used to evaluate the expression of the HSP70 and TLR4 in HepG2 cells and ELISA was used to detect the concentration of HSP70 in cell culture medium. A thermal tolerance HepG2 (HepG2TT) cell model was established to simulate HSP70 accumulation in the microenvironment. A certain concentration of curcumin was co-cultured with HepG2 and HepG2TT cells to observe the changes of HSP70 and TLR4. Our results revealed that heat stress significantly increased the expression of extracellular HSP70 (eHSP70) and TLR4 (P<0.01), but significantly reduced the expression of intracellular HSP70 (P<0.01). Curcumin inhibited proliferation, invasion, and metastasis of HepG2 cells, caused cells to remain in the DNA S phase, promoted apoptosis, and significantly reduced intracellular HSP70, eHSP70 and TLR4 levels of HepG2TT cells. Following the removal of curcumin, eHSP70 increased again. In summary, our results demonstrated that the antitumor effect of curcumin was related to the inhibition HSP70-TLR4 signaling.
2981 related Products with: Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling.Liver cancer tissue array Liver cancer and normal t Liver cancer tissue array Liver cancer survey tissu Liver cancer survey tissu Liver cancer tissue array Mid advanced stage liver Liver cancer and normal t High density liver cancer Colon cancer, metastasize Liver cancer survey tissu Liver cancer test tissue
#28054753 // Save this To Up
T-helper 2 cytokine-induced heat shock protein 70 secretion and its potential association with allergic rhinitis.Various inflammatory mediators have been found to be involved in the pathogenesis of allergic disease (AR). The role of heat shock proteins in AR has not been studied. The aim of this study was to investigate the levels of heat shock protein 70 (Hsp70) in the nasal lavage fluids of AR patients and controls to elucidate the role of Hsp70 in the pathogenesis of AR.
2352 related Products with: T-helper 2 cytokine-induced heat shock protein 70 secretion and its potential association with allergic rhinitis.Heat Shock 70kDa Protein HSP90C | alfa HSP90C, hea Heat Shock Protein 90, hu Heat Shock Protein 22, hu Heat Shock Protein 70, hu Heat shock protein 70 HS Rabbit heat shock protein Heat Shock Protein 65, my Mouse Anti-Heat Shock Pro Heat Shock Protein 70 (H Heat Shock Protein 20, hu Heat Shock Protein 70, hu
#27872147 // Save this To Up
Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.The target autoantigens in several organ-specific autoimmune diseases, including type 1 diabetes (T1D), are intracellular membrane proteins, whose initial encounter with the immune system is poorly understood. Here we propose a new model for how these proteins can initiate autoimmunity. We found that rat and human pancreatic islets release the intracellular β-cell autoantigens in human T1D, GAD65, IA-2, and proinsulin in exosomes, which are taken up by and activate dendritic cells. Accordingly, the anchoring of GAD65 to exosome-mimetic liposomes strongly boosted antigen presentation and T-cell activation in the context of the human T1D susceptibility haplotype HLA-DR4. Cytokine-induced endoplasmic reticulum stress enhanced exosome secretion by β-cells; induced exosomal release of the immunostimulatory chaperones calreticulin, Gp96, and ORP150; and increased exosomal stimulation of antigen-presenting cells. We propose that stress-induced exosomal release of intracellular autoantigens and immunostimulatory chaperones may play a role in the initiation of autoimmune responses in T1D.
1975 related Products with: Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.Macrophage Colony Stimula Macrophage Colony Stimula Cytokine (Human) Antibody Cytokine (Human) Antibody Beta Amyloid (1 40) ELISA Cytokine (Human) Antibody Goat Anti-Human GAD2 GAD6 Cytokine (Human) Antibody Rabbit Anti-Human Androge Anti beta3 AR Human, Poly Rabbit Anti-Human Androge GFP Expressing Human Inte
#27011219 // Save this To Up
Urine heat shock protein 70 levels as a marker of urinary tract infection in children.Heat shock proteins (HSPs) are a multi-family group of proteins which are upregulated by the cell in response to exposure to hazardous (stress) factors, including infectious agents, to prevent changes in protein structure. The aim of our study was to assess whether urine levels of the 70-kDa family of HSPs (HSP70s) increase in children with urinary tract infection (UTI) and to determine the optimal urine (u) HSP70 cut-off level to predict UTI in children.
1528 related Products with: Urine heat shock protein 70 levels as a marker of urinary tract infection in children.HSP90C | alfa HSP90C, hea Rabbit heat shock protein Heat Shock 70kDa Protein MarkerGeneTM Live Dead As Rabbit heat shock protein Mouse Anti-Heat Shock Pro MarkerGene™ Total Prote Mouse Anti-Heat Shock Pro Mouse Anti-Heat Shock Pro CD19 & CD82 Protein Prote RASGRP4 & RAP1A Protein P MAPKAPK5 & EIF4EBP1 Prote
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45 Fax 0032 16 50 90 45
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50 Fax 01 43 25 01 60
52062 Aachen Deutschland
Tel 0241 40 08 90 86 Fax 0241 55 91 05 36
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
Schweiz Züri +41435006251
Česká republika Praha +420246019719
Ireland Dublin +35316526556
Norge Oslo +4721031366
Finland Helsset +358942419041
Sverige Stockholm +46852503438
Ελλάς Αθήνα +302111768494
Magyarország Budapest +3619980547
GENTAUR Poland Sp. z o.o.
ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
Tel 058 710 33 44
Fax 058 710 33 48
GENTAUR Nederland BV
5521 DG Eersel Nederland
Tel 0208-080893 Fax 0497-517897
Piazza Giacomo Matteotti, 6, 24122 Bergamo
Tel 02 36 00 65 93 Fax 02 36 00 65 94
53 Iskar Str. 1191 Kokalyane, Sofia