Search results for: DAB Chromogen Substrate Kit
#16648798 // To Up
Effects of melatonin on the process of apoptosis in rat thyroid follicular cells.
Apoptosis, or programmed cell death, is a normal component in the development of multicellular organisms and is essential for many physiological processes. Apoptosis is a process in which cells play an active role in their own death (apoptosis is often referred to as "cell suicide"). Disturbances of apoptosis regulation can result in many diseases. Certain substances (for example--aflatoxin B1; AFB1) can induce apoptosis in various organs and tissues. Melatonin (Mel) is a hormone (indoleamine) which has antioxidant, antiproliferative and, potentially, anticancerogenic activities. The aim of our study was to examine the influence of late-afternoon (1600-1800) intraperitoneal (i.p.) Mel injections, administered for 3 weeks, on the process of apoptosis in male Wistar rat thyroid follicular cells (TFC); Mel was injected alone or together with AFB1 (i.p., also once daily for 3 weeks).Adam Gesing, Joanna Jagiela, Andrzej Lewinski
2349 related Products with: Effects of melatonin on the process of apoptosis in rat thyroid follicular cells.
96 wells1x10e7 cells2 Pieces/Box 5 G100ug100 µg 100 UG100 ug10 ugRelated Pathways
#14647002 // To Up
Melatonin does not affect p21 expression in rat thyroid follicular cells.
The cell-cycle (cc) is, in part, controlled by cyclin-dependent kinases (CDKs), which are activated after binding cyclins (positive regulators of cc). CDK inhibitors (CDKIs), such as p15, p16, p21, and p27, inhibit cyclin-CDK complex activity, and function as negative cell cycle regulators, blocking cell-cycle progression. The aim of our study was to examine the influence of late-afternoon (1600-1800) subcutaneous (s.c.) melatonin (Mel) injections, administered for 2 weeks, on the p21 expression in male Wistar rat thyroid follicular cells (TFC).Adam Gesing, Joanna Jagiela, Andrzej Lewinski
1727 related Products with: Melatonin does not affect p21 expression in rat thyroid follicular cells.
100 μg1x10e7 cells10 rxns96 wells200Related Pathways
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