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Search results for: Delapril hydrochloride CAS: [83435-67-0]

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Pharmacokinetics and tolerability of a new manidipine and delapril fixed oral combination in young and elderly subjects.

The aim of the present study was to compare the pharmacokinetic and pharmacodynamic properties of a fixed combination tablet containing 10 mg of manidipine dihydrochloride (CAS 89226-75-5), a calcium channel antagonist, and 30 mg of delapril hydrochloride (CAS 83435-67-0), an angiotensin converting enzyme (ACE) inhibitor, during once daily repeated dosing in young and elderly subjects and to assess the bioequivalence of the fixed combination tablet and the single ingredient tablets taken simultaneously in young healthy subjects after a single dose administration.
Armel Stockis, Steven De Bruyn, Christophe Gengler, Fabienne Goethals, Simone Lens, Gianluigi Poli, Daniela Acerbi

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25 mg1000 tests100ul200ul50 ug 100 mg10 mg200ug10 mg100ug1,000 tests

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