Only in Titles

Search results for: Human FGF-4 ELISA (For Lysates) ELISA

paperclip

#28376106   2017/04/04 To Up

Electrochemical sensor for rapid determination of fibroblast growth factor receptor 4 in raw cancer cell lysates.

The first electrochemical immunosensor for the determination of fibroblast growth factor receptor 4 (FGFR4) biomarker is reported in this work. The biosensor involves a sandwich configuration with covalent immobilization of a specific capture antibody onto activated carboxylic-modified magnetic microcarriers (HOOC-MBs) and amperometric detection at disposable carbon screen-printed electrodes (SPCEs). The biosensor exhibits a great analytical performance regarding selectivity for the target protein and a low LOD of 48.2 pg mL-1. The electrochemical platform was successfully applied for the determination of FGFR4 in different cancer cell lysates without any apparent matrix effect after a simple sample dilution and using only 2.5 μg of the raw lysate. Comparison of the results with those provided by a commercial ELISA kit shows competitive advantages by using the developed immunosensor in terms of simplicity, analysis time, and portability and cost-affordability of the required instrumentation for the accurate determination of FGFR4 in cell lysates.
Rebeca M Torrente-Rodríguez, Víctor Ruiz-Valdepeñas Montiel, Susana Campuzano, María Pedrero, Meryem Farchado, Eva Vargas, F Javier Manuel de Villena, María Garranzo-Asensio, Rodrigo Barderas, José M Pingarrón

2075 related Products with: Electrochemical sensor for rapid determination of fibroblast growth factor receptor 4 in raw cancer cell lysates.

2 Pieces/Box100 μg400Tests0.1 mg10 ug5ug96 wells (1 kit)1 kit(96 Wells)96 wells (1 kit)100.00 ug5 x 50 ug0.1 mg

Related Pathways

paperclip

#14504053   // To Up

Marked increase of the growth factors pleiotrophin and fibroblast growth factor-2 in serum of testicular cancer patients.

Malignant tumors of the testis are among the most common cancers in men between the ages of 15 and 30 years. The sensitivity of detection of known tumor markers depends upon the tumor histology and stage. In other cancers, increased serum concentrations of various angiogenic growth factors have been described as potential markers for tumor progression and metastasis. One main histological feature of testicular cancer is profound angiogenesis.
A Aigner, P Brachmann, J Beyer, R Jäger, D Raulais, M Vigny, A Neubauer, A Heidenreich, S Weinknecht, F Czubayko, G Zugmaier

2522 related Products with: Marked increase of the growth factors pleiotrophin and fibroblast growth factor-2 in serum of testicular cancer patients.

100 μg20ug0.1ml (1mg/ml)100.00 ug10ug10ug10ug5ug2ug2ug x 205ug100.00 ug

Related Pathways