Only in Titles

           Search results for: Monoclonal Anti Death Associated Protein Kinase produced in mouse    

paperclip

#30711629   // Save this To Up

MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.

Inhibitors of MET have not produced satisfactory outcomes in trials of patients with liver cancer. We investigated the mechanisms of liver tumor resistance to MET inhibitors in mice.

1624 related Products with: MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.

Tissue array of ovarian g Multiple organ tumor tiss Breast cancer tissue arra Liver cancer tissue array Liver late stage tumor ti Multiple organ cancer tis EnzyChrom™ Kinase Assay Liver tumor tissue array, Multiple tumor tissue arr Colon cancer, metastasize 2-Azido-2-deoxy-D-galactu anti-5-Methylcytosine (an

Related Pathways

paperclip

#11692177   // Save this To Up

NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro.

Using primary cultures of human pancreatic islets, purified human pancreatic beta cells and the mouse beta TC6-F7 cell line, we analysed the expression of nerve growth factor, (NGF/NGF) receptors in beta cells. To investigate whether NGF could sub-serve an autocrine antiapoptotic role in beta cells, we studied the effects of NGF withdrawal using a neutralizing monoclonal anti-NGF antibody.

2985 related Products with: NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro.

Glucagon ELISA KIT, Rat G MarkerGeneTM in vivo lacZ Rabbit Anti-Integrin beta Apoptosis Phospho-Specifi Interleukins Recombinant Rabbit Anti-Integrin beta Phospho Integrin Beta 3 Y Indoxyl beta D glucuronid Pancreatic cancer test ti TGF beta induced factor 2 Anti Apoptosis Inducing F Mid advanced stage pancre

Related Pathways

paperclip

#10965998   // Save this To Up

The growth and metastasis of human, HER-2/neu-overexpressing tumor cell lines in male SCID mice.

HER-2/neu is overexpressed on a variety of human adenocarcinomas and overexpression has been associated with a poor prognosis. For this reason, HER-2 has become an attractive target for immunotherapy. To facilitate testing of anti-HER-2-monoclonal antibodies (MAbs) and immunotoxins (ITs), we have evaluated the in vivo growth and metastatic spread of three HER-2-overexpressing human breast cancer cell lines (BT474, MDA-MB-453 and HCC1954) and one ovarian cancer cell line (SKOV3.ip1) in pre-irradiated male SCID mice using subcutaneous (s.c.), intravenous (i.v.) and intraperitoneal (i.p.) routes of injection. All the cell lines tested grew as s.c. tumors and the growth of BT474 and MDA-MB-453 cells after s.c. injection was improved by co-inoculation with Matrigel. Metastases to the lungs were detectable by PCR or histopathology after s.c. injection of BT474 and to a much lesser extent after s.c. injection of HCC1954, MD-MB-453 and SKOV3.ip1 cells. I.p. injection of HCC1954 and SKOV3.ip1 cells produced fatal ascites while i.v. injection of SKOV3.ip1, but not BT474 or MDA-MB-453 cells, resulted in infiltration of lungs and death within 9-11 weeks.

2652 related Products with: The growth and metastasis of human, HER-2/neu-overexpressing tumor cell lines in male SCID mice.

Human tumor cell array, 1 Human tumor cell array, 1 Tissue array of ovarian g CELLKINES Natural Human I Macrophage Colony Stimula Anti C Reactive Protein A Rabbit Anti-Cell death in Human Large Intestine Mic Multiple organ tumor tiss Multiple organ tumor tiss Human Insulin-like Growth Goat Anti-Human Synaptogy

Related Pathways