Only in Titles

Search results for: Mouse Anti-Human CD57 Antibodies

paperclip

#10880835   // To Up

Establishment and usefulness of an anti-human CD57 IgG1 monoclonal antibody.

In the present study we established a new monoclonal antibody, JNK-1, which recognizes all cells recognized by CD57/HNK-1 mAb. JNK-1 and CD57 mAbs inhibited the binding of each other, suggesting that the molecules they recognize are either identical or sufficiently close to cause steric hindrance in the binding assay. JNK-1 mAb detected the 110-kDa protein, which is identical to the protein recognized by CD57/HNK-1 mAb in Western immunoblot analysis combined with immunoprecipitation. Therefore, JNK-1 mAb appears to recognize homogeneous molecules identified by the currently available CD57 mAb. Notably, JNK-1 mAb is composed of mouse IgG1 heavy chains, and thus can be used easily in immunoprecipitation, which cannot easily be performed with the available CD57 mAb because it is an IgM isotype. Thus, JNK-1, which is an IgG isotype, may present a useful tool to elucidate the CD57 protein.
J Tajima, Y Heike, K Kato, Y Ikarashi, R Asada-Mikami, M Yoshida, T Kasahara, H Wakasugi

1697 related Products with: Establishment and usefulness of an anti-human CD57 IgG1 monoclonal antibody.

1 mg100 TESTS1 ml1 mg100 ul0.2 mg0.1 mg100 ul0.1 mg0.l mg0.1 mg0.1 mg

Related Pathways