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The detection of SAS1B in serum provides clues for early diagnosis of thyroid cancer.

The incidence of thyroid cancer is rising globally. Most patients progress slowly, but some patients develop lymph node and distant metastasis earlier, and their prognosis is poor. Therefore, early diagnosis and warning of malignancy are very meaningful for such patients. SAS1B gene is a newly discovered protein expressed on the surface of mature egg cells and has metalloendopeptidase activity. We aimed at exploring whether SAS1B is involved in the occurrence of thyroid cancer, and at providing evidence for early diagnosis and targeted therapy of thyroid cancer.
H-X Yang, Y Yang, X-D Li, X-M Miao, C Yang, D-F Zhi, H Su, G Yang, J Gao, C-G Du, H-J Li, Y-L Song, G-F Cao

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