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Search results for: Rabbit Anti-Human SARS Receptor ACE2 Antibodies

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Strong ACE-2 expression in the choroidal vessels: do high choroid plexuses serve as a gateway for SARS-CoV-2 infection on the human brain?

Previous studies have confirmed the key mechanism by which SARS-CoV-2 enters human cells. It is well established that ACE2 is the receptor that can mark the beginning of the infection. In light of this, the organs that express higher levels of ACE2 are generally considered at higher risk, while those with lower levels should be somehow more protected. This - if related to the scarcity of ace2-expressing cells in the brain - seems to contrast with the presence of a variety of neurological symptoms that follow infection with ace2.  The aim of this work was to analyze ACE2 expression in the human brain, focusing on the choroid plexuses.
M Piras, F Cau, M Manchia, P Paribello, L Saba, J S Suri, G Faa, G Pichiri, G Cerrone, A Scano, G Orrù, G La Nasa, F Coghe, M Castagnola, D Fanni, C Gerosa

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