Search results for: Rat monoclonal anti mouse Interleukin 17 Anti-Mouse antibodies
#28240383 2017/02/27 To Up
Targeting Th17-IL-17 Pathway in Prevention of Micro-Invasive Prostate Cancer in a Mouse Model.
Chronic inflammation has been associated with the development and progression of human cancers including prostate cancer. The exact role of the inflammatory Th17-IL-17 pathway in prostate cancer remains unknown. In this study, we aimed to determine the importance of Th17 cells and IL-17 in a Pten-null prostate cancer mouse model.Qiuyang Zhang, Sen Liu, Dongxia Ge, David M Cunningham, Feng Huang, Lin Ma, Thomas P Burris, Zongbing You
2290 related Products with: Targeting Th17-IL-17 Pathway in Prevention of Micro-Invasive Prostate Cancer in a Mouse Model.
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#26717421 2015/12/21 To Up
TNF-α enhance Th2 and Th17 immune responses regulating by IL23 during sensitization in asthma model.
TNF-α has been postulated to be a critical mediator contributing to airway inflammation. The purpose of this study was to evaluate the role of TNF-α in the induction of Th17 and Th2 cells related to asthma pathogenesis.Hyun Seung Lee, Heung-Woo Park, Woo-Jung Song, Eun Young Jeon, Boram Bang, Eun-Jin Shim, Hyung-Geun Moon, Yoon-Keun Kim, Hye-Ryun Kang, Kyung-Up Min, Sang-Heon Cho
2401 related Products with: TNF-α enhance Th2 and Th17 immune responses regulating by IL23 during sensitization in asthma model.
4 Arrays/Slide18 kgs2 Pieces/BoxRelated Pathways
#23939174 // To Up
[Neutralization of interleukin-17 aggravates respiratory infection induced by Chlamydia trachomatis in mice].
To evaluate the role of interleukin-17 (IL-17) in respiratory infection with Chlamydia trachomatis in mice.Xiao-yun Zhang, Qi Li, Ying-qian Zhang
2030 related Products with: [Neutralization of interleukin-17 aggravates respiratory infection induced by Chlamydia trachomatis in mice].
96 wells (1 kit)5ug5ug5ug 0.1 mg 5 100.00 ug1000 500 96 tests96 wells (1 kit)1 mgRelated Pathways
#14962796 // To Up
Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.
We evaluated the effects of rat anti-mouse IL-17 neutralizing monoclonal antibody (mAb) on the development of dextran sulfate sodium (DSS)-induced colitis. Tissue samples were evaluated by standard immunohistochemical procedure. The mucosal mRNA expression of cytokines was analyzed by reverse transcriptase-polymerase chain reaction (RT-PCR). In the mice treated with the anti-IL-17 mAb, the body weight was significantly lower, and anal prolapse and colon shortening were apparent. A histological analysis indicated that the anti-IL-17 mAb markedly enhanced the severity of colitis. The mucosal infiltration of CD4-positive helper T cells and CD11b-positive granulocytes-monocytes was increased in the anti-IL-17 mAb-treated mice. Treatment with the anti-IL-17 mAb increased the mucosal expression of mRNAs of tumor necrosis factor (TNF)-alpha, interferon (IFN)-gamma, IL-6, RANTES, and IP-10. Blocking of IL-17 activity in vivo using the anti-IL-17 mAb enhanced the development of DSS-colitis in mice. This suggests an inhibitory role for IL-17 in the development of DSS-colitis.Atsuhiro Ogawa, Akira Andoh, Yoshio Araki, Tadao Bamba, Yoshihide Fujiyama
1239 related Products with: Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.
5ug5ug5ug96 wells (1 kit) 0.1 mg 2 16-22 Sample Kit500 10 96T100 ul10Related Pathways
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