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           Search results for: Recombinant Human C1QTNF6 Proteins    

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#26648301   2015/12/09 Save this To Up

[C1q tumor necrosis factor-related protein 6 (CTRP6) inhibits the proliferation and migration of ovarian cancer cells].

To explore the role of C1q tumor necrosis factor-related protein 6 (CTRP6) in the proliferation and migration of ovarian cancer cells.

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Human, Complement C1q tum RANK Ligand Soluble, Huma Tissue array of ovarian g ELISA Kit for Tumor Necr Epidermal Growth Factor ( Epidermal Growth Factor ( Human Tumor Necrosis Fact Human Tumor Necrosis Fact TNFRSF1B - Goat polyclona Mouse Tumor Necrosis Fact Rat Tumor Necrosis Factor Combined multiple normal

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#26404464   2015/09/25 Save this To Up

CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis.

The complement system is important for the host defence against infection as well as for the development of inflammatory diseases. Here we show that C1q/TNF-related protein 6 (CTRP6; gene symbol C1qtnf6) expression is elevated in mouse rheumatoid arthritis (RA) models. C1qtnf6(-/-) mice are highly susceptible to induced arthritis due to enhanced complement activation, whereas C1qtnf6-transgenic mice are refractory. The Arthus reaction and the development of experimental autoimmune encephalomyelitis are also enhanced in C1qtnf6(-/-) mice and C1qtnf6(-/-) embryos are semi-lethal. We find that CTRP6 specifically suppresses the alternative pathway of the complement system by competing with factor B for C3(H2O) binding. Furthermore, treatment of arthritis-induced mice with intra-articular injection of recombinant human CTRP6 cures the arthritis. CTRP6 is expressed in human synoviocytes, and CTRP6 levels are increased in RA patients. These results indicate that CTRP6 is an endogenous complement regulator and could be used for the treatment of complement-mediated diseases.

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Anti AGO2 Human, Monoclon Anti AGO2 Mouse, Monoclon Anti AGO2 Human, Monoclon Anti AGO2 Mouse, Monoclon Candida albicans antibody Mouse anti Canine IgE ant Mouse anti Canine IgE ant Mouse anti Canine IgE ant Mouse anti Canine IgE ant steroidogenic acute regul serologically defined col Rabbit Anti-ZHX2 Alpha fe

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#21508531   2011/07/07 Save this To Up

Expression of a secretory protein C1qTNF6, a C1qTNF family member, in hepatocellular carcinoma.

Recent studies have revealed that the adiponectin-associated protein belonging to the C1qTNF family mediates various biological processes. However, the pathobiological property of C1qTNF6 in carcinogenesis remains unclear. Here, we investigated the expression status of C1qTNF6 in human hepatocellular carcinomas and subsequently attempted to determine the role of C1qTNF6 in tumor neovascularization.

2152 related Products with: Expression of a secretory protein C1qTNF6, a C1qTNF family member, in hepatocellular carcinoma.

G protein-coupled recepto amyloid beta precursor pr EGF Phospho-Specific Arra Liver hepatocellular carc Hepatocellular carcinoma Hepatocellular carcinoma Hepatocellular carcinoma Hepatocellular carcinoma Normal liver and hepatoce HIV 1 intergase antigen. DNA (cytosine 5) methyltr Human Macrophage Inflamma

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