Search results for: Sheep Anti-Austrelaps spp. Venom Antibodies
#35960772 
2022/08/12
To Up
Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of the medically most important Bitis spp. and Echis spp. African snakes.
Snakebite envenomation exerts a heavy toll in sub-Saharan Africa. The design and production of effective polyspecific antivenoms for this region demand a better understanding of the immunological characteristics of the different venoms from the most medically important snakes, to select the most appropriate venom combinations for generating antivenoms of wide neutralizing scope. Bitis spp. and Echis spp. represent the most important viperid snake genera in Africa.Aarón Gómez, Andrés Sánchez, Gina Durán, Daniel Cordero, Álvaro Segura, Mariángela Vargas, Daniela Solano, María Herrera, Stephanie Chaves-Araya, Mauren Villalta, Melvin Sánchez, Mauricio Arguedas, Cecilia Díaz, José María Gutiérrez, Guillermo León
1077 related Products with: Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of the medically most important Bitis spp. and Echis spp. African snakes.
100ug100ug100ug100ug100ug100ug100ug100ug100ug100ug100ug100ug
Related Pathways
#4003723 //
To Up
Crossed immunoelectrophoresis and crossed radioimmunoelectrophoresis analysis of "yellow jacket-common wasp" (Vespula spp.).
Crossed immunoelectrophoresis (CIE) pattern of Yellow jacket vespid venom showing 25 immunoprecipitates was used in crossed radioimmunoelectrophoresis (CRIE) analysis with sera from 35 subjects allergic to vespid venom. Phospholipase A and B, hyaluronidase, acid and alkaline phosphatases and a lytic active component were demonstrated in immunoprecipitates using zymography and direct haemolysis of sheep erythrocytes. CRIE analysis proved the allergenicity of these proteins. In addition, another antigen (Ag 17) with no detectable enzymatic or lytic activity was identified as an important allergen. This allergen is most likely identical to the previously described Antigen 5 in vespid venoms. By using CIE/CRIE the presence and complexity of multiple forms of the allergenic protein components were well demonstrated.R Einarsson, R Karlsson, B Olsson, T Uhlin, S Ohman