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#29054658   2017/10/21 Save this To Up

Influence of organic matter, nutrients, and cyclodextrin on microbial and chemical herbicide and degradate dissipation in subsurface sediment slurries.

Pesticides leaching from soil to surface and groundwater are a global threat for drinking water safety, as no cleaning methods occur for groundwater environment. We examined whether peat, compost-peat-sand (CPS) mixture, NH4NO3, NH4NO3 with sodium citrate (Na-citrate), and the surfactant methyl-β-cyclodextrin additions enhance atrazine, simazine, hexazinone, dichlobenil, and the degradate 2,6-dichlorobenzamide (BAM) dissipations in sediment slurries under aerobic and anaerobic conditions, with sterilized controls. The vadose zone sediment cores were drilled from a depth of 11.3-14.6m in an herbicide-contaminated groundwater area. The peat and CPS enhanced chemical atrazine and simazine dissipation, and the peat enhanced chemical hexazinone dissipation, all oxygen-independently. Dichlobenil dissipated under all conditions, while BAM dissipation was fairly slow and half-lives could not be calculated. The chemical dissipation rates could be associated with the chemical structures and properties of the herbicides, and additive compositions, not with pH. Microbial atrazine degradation was only observed in the Pseudomonas sp. ADP amended slurries, although the sediment slurries were known to contain atrazine-degrading microorganisms. The bioavailability of atrazine in the water phase seemed to be limited, which could be due to complex formation with organic and inorganic colloids. Atrazine degradation by indigenous microbes could not be stimulated by the surfactant methyl-β-cyclodextrin, or by the additives NH4NO3 and NH4NO3 with Na-citrate, although the nitrogen additives increased microbial growth.

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Androgen Receptor (Phosph Androgen Receptor (Phosph Rabbit Anti-Human Androge Rabbit Anti-Human Androge Androgen Receptor (Ab 650 AZD-3514 Mechanisms: Andr 17β-Acetoxy-2α-bromo-5 (5α,16β)-N-Acetyl-16-[2 (5α,16β)-N-Acetyl-16-ac 5α-N-Acetyl-2'H-androst- 5α-N-Acetyl-2'H-androst- 3-O-Acetyl 5,14-Androstad

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#29050474   2017/10/20 Save this To Up

Release of Solubilizate from Micelle upon Core Freezing.

By combining NMR (yielding 1H chemical shift, spin relaxation and self-diffusion data) and SAXS experiments, we investigate the complex temperature dependence of the molecular and aggregate states in aqueous solutions of the surfactant [CH3(CH2)17(OCH2CH2)20OH], abbreviated C18E20, and hexamethyldisiloxane HMDSO. The latter molecule serves as a model for hydrophobic solubilizates. Previously, the pure micellar solution was demonstrated to exhibit core freezing at approx. 7-8 °C. At room temperature, we find that HMDSO solubilizes at a volume fraction of approx. 10% in the core of the C18E20 micelles that consists of molten and thereby highly mobile alkyl chains. Upon lowering the temperature, core freezing is found just like in pure micelles but at a temperature shifted significantly to 3 °C. The frozen cores contain immobile alkyl chains and exhibit a higher density but are essentially devoid (volume fraction below 1%) of the solubilizate. The latter molecules are released, first gradually and then rather steeply, from the core in the temperature range which is roughly delimited by the two core freezing temperatures, one for pure micelles and one for micelles with solubilizates. The release behavior of systems with different initial HMDSO loading follows the same master curve. This feature is rationalized in terms of loading capacity that is strongly temperature dependent: Upon lowering the temperature, release commences once the loading capacity descends below the actual solubilizate content. The sharp release curves and the actual release mechanism with its molecular features shown in rich detail have some bearing on a diverse class of possible applications.

2519 related Products with: Release of Solubilizate from Micelle upon Core Freezing.

Hepatitis B Core Antigen Hepatitis B Core Antigen Hepatitis B Core Antigen Hepatitis B Core Antigen HbcAg - Hepatitis B Viru HbcAg - Hepatitis B Viru HbcAg - Hepatitis B Viru HCV core recombinant anti HCV core recombinant anti HCV core recombinant anti HCV core recombinant anti HBV core recombinant anti

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#29049375   2017/10/19 Save this To Up

Intratumoral heterogeneity of programmed cell death ligand-1 expression is common in lung cancer.

Programmed cell death ligand-1 (PD-L1) expression may predict the response to both programmed cell death-1 and PD-L1 inhibitors in lung cancer. However, the extent of intratumoral heterogeneity of PD-L1 expression, which may cause false negative results, is largely unexplored. We aimed to assess the intratumoral heterogeneity of PD-L1 expression in surgically resected lung cancer specimens by applying a novel method of tissue microarray, namely Spiral Arrays, which enables us to observe the heterogeneity in spiral-shaped tissue cores. Adenocarcinoma and squamous cell carcinoma specimens were obtained from consecutive patients with lung cancer who had undergone surgical resection at Nagasaki University Hospital (Nagasaki, Japan) since 2009. Small cell lung cancer and large cell carcinoma specimens were selected from patients in the same archive who had undergone resection since 1998. Spiral Arrays were constructed of spiral-shaped cores, prepared from representative blocks of each case, which were subjected to immunohistochemistry using an anti-PD-L1 antibody. Each core was divided into 8 segments and each segment was classified as either PD-L1-positive or PD-L1-negative using thresholds of 1.0%, 5.0%, 10.0%, and 50.0%, respectively. In total, 138 specimens were selected, including 60 adenocarcinomas, 59 squamous cell carcinomas, 12 small cell lung cancers, and 7 large cell carcinomas. The majority of specimens with PD-L1-positive segments exhibited heterogeneous expression (i.e., had a mixture of PD-L1-positive and PD-L1-negative segments within a core) irrespective of the threshold (1.0%, 66.7%; 5.0%, 74.4%; 10.0%, 75.8%; and 50.0%, 85.7%]. Large variations in the ratios of PD-L1-positive segments were observed. At least 50.0% of the segments within a core were negative in no fewer than 50.0% (range, 50.0-76.0%) of cases with heterogeneous PD-L1 expression. In conclusion, intratumoral heterogeneity of PD-L1 expression was frequently observed in cases of lung cancer. Thus, multiple tumor biopsy specimens may be needed to accurately determine the PD-L1 expression status.

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#29049307   2017/10/19 Save this To Up

DOMe: A deduplication optimization method for the NewSQL database backups.

Reducing duplicated data of database backups is an important application scenario for data deduplication technology. NewSQL is an emerging database system and is now being used more and more widely. NewSQL systems need to improve data reliability by periodically backing up in-memory data, resulting in a lot of duplicated data. The traditional deduplication method is not optimized for the NewSQL server system and cannot take full advantage of hardware resources to optimize deduplication performance. A recent research pointed out that the future NewSQL server will have thousands of CPU cores, large DRAM and huge NVRAM. Therefore, how to utilize these hardware resources to optimize the performance of data deduplication is an important issue. To solve this problem, we propose a deduplication optimization method (DOMe) for NewSQL system backup. To take advantage of the large number of CPU cores in the NewSQL server to optimize deduplication performance, DOMe parallelizes the deduplication method based on the fork-join framework. The fingerprint index, which is the key data structure in the deduplication process, is implemented as pure in-memory hash table, which makes full use of the large DRAM in NewSQL system, eliminating the performance bottleneck problem of fingerprint index existing in traditional deduplication method. The H-store is used as a typical NewSQL database system to implement DOMe method. DOMe is experimentally analyzed by two representative backup data. The experimental results show that: 1) DOMe can reduce the duplicated NewSQL backup data. 2) DOMe significantly improves deduplication performance by parallelizing CDC algorithms. In the case of the theoretical speedup ratio of the server is 20.8, the speedup ratio of DOMe can achieve up to 18; 3) DOMe improved the deduplication throughput by 1.5 times through the pure in-memory index optimization method.

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QuantiChrom™ Formaldehy MOUSE ANTI BOVINE ROTAVIR Bone Morphogenetic Protei Growth Differentiation Fa Amplite™ Fluorimetric F MOUSE ANTI BORRELIA BURGD succinate-CoA ligase, GDP TCP-1 theta antibody Sour formin-like 1 antibody So succinate-CoA ligase, ADP Primary antibody Caspase Primary antibody FLIP An

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#29048732   2017/10/19 Save this To Up

Chemical Stimulus-responsive Folding and Unfolding of a Dendrimeric Assembly.

A dendrimeric trimer undergoes folding and unfolding in response to chemical stimulus. The trimer of interest contains a central dendrimer with a butadiyne-linked zinc porphyrin dimer ((ZnP)₂) core, in addition to two terminal dendrimers with zinc porphyrin (ZnP) cores. The obtained absorption spectra indicate that the unfolded form is the exclusive conformer in chloroform, while the addition of 1,4-diazabicyclo[2.2.2]octane (DABCO) in chloroform leads to transformation from the unfolded to the folded structure containing two DABCO units per trimer; the folded structure originates from the cross-linking of (ZnP)₂ and ZnP with DABCO. Moreover, the addition of excess DABCO promotes the generation of the unfolded structure containing four DABCO units.

1740 related Products with: Chemical Stimulus-responsive Folding and Unfolding of a Dendrimeric Assembly.

Anti VGLUT 1 Rat, polyclo Anti Rat VGLUT 2, Rabbit Androgen Receptor (Phosph Androgen Receptor (Phosph Rabbit Anti-Human Androge Rabbit Anti-Human Androge Androgen Receptor (Ab 650 AZD-3514 Mechanisms: Andr 17β-Acetoxy-2α-bromo-5 (5α,16β)-N-Acetyl-16-[2 (5α,16β)-N-Acetyl-16-ac 5α-N-Acetyl-2'H-androst-

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#29048390   2017/10/19 Save this To Up

Enhanced UV-Visible Light Photocatalytic Activity by Constructing Appropriate Heterostructures between Mesopore TiO₂ Nanospheres and Sn₃O₄ Nanoparticles.

Novel TiO₂/Sn₃O₄ heterostructure photocatalysts were ingeniously synthesized via a scalable two-step method. The impressive photocatalytic abilities of the TiO₂/Sn₃O₄ sphere nanocomposites were validated by the degradation test of methyl orange and •OH trapping photoluminescence experiments under ultraviolet (UV) and visible light irradiation, respectively. Especially under the visible light, the TiO₂/Sn₃O₄ nanocomposites demonstrated a superb photocatalytic activity, with 81.2% of methyl orange (MO) decomposed at 30 min after irradiation, which greatly exceeded that of the P25 (13.4%), TiO₂ (0.5%) and pure Sn₃O₄ (59.1%) nanostructures. This enhanced photocatalytic performance could be attributed to the mesopore induced by the monodispersed TiO₂ cores that supply sufficient surface areas and accessibility to reactant molecules. This exquisite hetero-architecture facilitates extended UV-visible absorption and efficient photoexcited charge carrier separation.

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DyNA Light UV Transillumi Rapid Microplate Assay K Kappa Light Chain Kappa Light Chain Lambda Light Chain Lambda Light Chain Kappa Light Chain Lambda Light Chain Light Green Solution Light Green Solution Light Green Solution Light Green S.F. Yellowi

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#29047562   2017/10/19 Save this To Up

High-order mode conversion based on adiabatical mode evolution for mode division multiplexing applications.

Mode conversion based on adiabatical mode evolution in a two-core configuration is investigated. The configuration can convert all the launching modes to higher-order modes from one port and convert all the launching modes to lower-order modes from another port. Mode conversion between the two degenerated high-order modes is also demonstrated numerically. The mode conversion feature is only dependent on the relationship between the effective mode indices of the two cores in the configuration, which shows the characteristics of high flexibility and large fabrication tolerance.

2351 related Products with: High-order mode conversion based on adiabatical mode evolution for mode division multiplexing applications.

Model 150 V T Ultrasonic ULTRASONIC HOMOGENIZERS: Model 300 V T Ultrasonic ULTRASONIC HOMOGENIZERS: Model 3000 Ultrasonic Hom ULTRASONIC HOMOGENIZERS: Horizontal Laminar Flow Horizontal Laminar Flow Horizontal Laminar Flow Vertical Laminar Flow Cle Vertical Laminar Flow Cle Horizontal Laminar Flow

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#29047557   2017/10/19 Save this To Up

Generating superimposed Bessel beams with a volume holographic axicon.

Quasi-Bessel beams (QBB) with different profiles are generated with an axicon-telescope system. Beam profiles are found to vary with different axicon-telescope distance δ. QBBs are stored as volume holograms in a photorefractive crystal. Reconstructions of the QBBs are focused by the recording axicon to produce superimposed Bessel beams (SBBs) with oscillating cores. SBBs formed through this method have different oscillation periods that range from 4.3 to 6.1 cm. We demonstrate that periodicity is dependent on δ. Our method allows tunability of the SBB period through a simple rearrangement of optical elements.

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#29046837   2017/10/19 Save this To Up

Fabrication of carbon nanospheres by the pyrolysis of polyacrylonitrile-poly(methyl methacrylate) core-shell composite nanoparticles.

Carbon nanospheres with a high Brunauer-Emmett-Teller (BET) specific surface area were fabricated via the pyrolysis of polyacrylonitrile-poly(methyl methacrylate) (PAN-PMMA) core-shell nanoparticles. Firstly, PAN-PMMA nanoparticles at high concentration and low surfactant content were controllably synthesized by a two-stage azobisisobutyronitrile (AIBN)-initiated semicontinuous emulsion polymerization. The carbon nanospheres were obtained after the PAN core domain was converted into carbon and the PMMA shell was sacrificed via the subsequent heat treatment steps. The thickness of the PMMA shell can be easily adjusted by changing the feeding volume ratio (FVR) of methyl methacrylate (MMA) to acrylonitrile (AN). At an FVR of 1.6, the coarse PAN cores were completely buried in the PMMA shells, and the surface of the obtained PAN-PMMA nanoparticles became smooth. The thick PMMA shell can inhibit the adhesion between carbon nanospheres caused by cyclization reactions during heat treatment. The carbon nanospheres with a diameter of 35-65 nm and a high BET specific surface area of 612.8 m(2)/g were obtained from the PAN-PMMA nanoparticles synthesized at an FVR of 1.6. The carbon nanospheres exhibited a large adsorption capacity of 190.0 mg/g for methylene blue, thus making them excellent adsorbents for the removal of organic pollutants from water.

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1H-1-Acetylimino-3-methyl N-[[4-[[(4-Amino[1,1'-bip N-[[4-[[(4-Amino[1,1'-bip 3-[[[5-Aminocarbonyl-1-me 3-[[[5-(Aminocarbonyl)-1- 1-Amino-3-methylisoquinol 2-Amino-4-(4-methylphenyl 4-O-Benzyl-N-[(benzyloxy) 4-O-Benzyl-N-[(benzyloxy) 4-O-Benzyl-N-[(benzyloxy) Benzyl Methyl Carbonate C Benzyl [1-[4-[[(4-Fluorob

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#29045792   2017/10/18 Save this To Up

Glycopeptides as Targets for Dendritic Cells: Exploring MUC1 Glycopeptides Binding Profile Towards Macrophage Galactose-Type Lectin (MGL) Orthologs.

The macrophage galactose-type lectin (MGL) recognises glycan moieties exposed by pathogens and malignant cells. Particularly, mucin-1 (MUC1) glycoprotein presents an altered glycosylation in several cancers. To estimate the ability of distinct MGL orthologs to recognise aberrant glycan cores in mucins, we applied evanescent-field detection to a versatile MUC1-like glycopeptide microarray platform. Here, as binding was sequence-dependent, we demonstrated that not only sugars, but also peptide region, impacts the recognition of murine MGL1 (mMGL1). In addition, we observed for all three MGL orthologs that divalent glycan presentation increased the binding. To assess the utility of the glycopeptide binders of the MGL orthologs for MGL targeting, we performed uptake assays with fluorescein-MUC1 using murine dendritic cells. A diglycosylated MUC1 peptide was preferentially internalized in an MGL-dependent fashion, thus showing the utility for divalent MGL targeting. These findings may be relevant to a rational design of anti-tumour vaccines targeting dendritic cells via MGL.

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Carboxyfluorescein diacet MOUSE ANTI BOVINE ROTAVIR Mouse anti-chick type I c Mouse anti-chick type I c Mouse anti-bovine type I Mouse anti-bovine type I Mouse anti-porcine type I Mouse anti-porcine type I Mouse anti-human type I c Mouse anti-mouse type I c Mouse anti-mouse type I c Rat anti-chick type I col

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