%PDF-1.6
%
1 0 obj
<>
endobj
2 0 obj
<>stream
2013-08-06T18:23:52+03:00
2013-08-06T18:23:52+03:00
2013-08-06T18:23:52+03:00
application/pdf
bs-4818R-Cy7
uuid:c6ec7adf-165f-4331-a522-26370bfaa28b
uuid:47f56320-833f-4a9c-93ee-320722303cce
Acrobat Web Capture 9.0
endstream
endobj
5 0 obj
<>
endobj
6 0 obj
<>
endobj
3 0 obj
<>
endobj
7 0 obj
<>
endobj
11 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC/ImageI]/XObject<>>>/Type/Page>>
endobj
12 0 obj
[29 0 R]
endobj
13 0 obj
<>stream
/CS0 cs 1 scn
10 815.726 574.5 -735.891 re
f
BT
0.2 scn
/TT0 1 Tf
6.6416 0 0 6.6416 21.2908 767.2422 Tm
(www.biossusa.com)Tj
0 -1.5 TD
(support@biossusa.com)Tj
-0.012 Tw 0 -1.5 TD
[(800.501.7654)-34( )1([DOMESTIC])]TJ
0 -1.5 TD
[(+1.781.569.5821)-57( )1([INTERNATIONAL])]TJ
ET
q
/GS0 gs
141.4664764 0 0 -79.6994171 438.3843994 810.412735 cm
/Im0 Do
Q
BT
0 scn
/TT1 1 Tf
0 Tw 9.2983 0 0 9.2983 21.2908 715.4376 Tm
[(bs)-67(-)-69(4818R)-12(-)-69(Cy7)]TJ
/TT0 1 Tf
-0.04 Tw 7.3058 0 0 7.3058 28.5965 668.9462 Tm
[(Conjugated)-58( Primary)-1( Antibodies)]TJ
/TT1 1 Tf
0 Tw 0 -2.091 TD
(Background:)Tj
/TT0 1 Tf
-0.04 Tw 0 -1.455 TD
[(CD45)-83( is)-52( a)-20( family)-88( of)-48( single)-4( chain)-33( transmembraneous)-47( glycoproteins)-76( consisting)-7( of)-48( at)-50( least)-31( four)-39( isoforms)-2( \(220,)-40( 205,)]TJ
0 -1.455 TD
[(190,)-59( 180)-89( kDa\))-7( which)-88( share)-40( a)-20( common)-33( large)-80( intracellular)-59( domain.)-85( Their)-16( extracellular)-7( domains)-33( are)-44( heavily)]TJ
0 -1.455 TD
[(glycosylated.)-29( The)-59( different)-5( isoforms)-2( are)-43( produced)-75( by)-40( alternative)-83( messenger)-37( RNA)-21( splicing)-15( of)-48( three)-60( exons)-68( of)-48( a)]TJ
0 -1.455 TD
[(single)-4( gene)-19( on)-81( chromosome)-67( 1.)-60( CD45)-84( is)-52( expressed)-23( on)-81( cells)-18( of)-48( the)-37( human)-52( hematopoietic)-72( lineage)-36( \(including)]TJ
T*
[(hematopoietic)-72( stem)-36( cells\))-90( with)-46( the)-37( exception)-48( of)-48( mature)-39( red)-15( cells.)-79( It)-20( is)-52( not)-19( detected)-5( on)-81( differentiated)-20( cells)-18( of)-48( other)]TJ
0 -1.455 TD
[(tissues.)-76( It)-20( is)-52( likely)-64( that)-67( CD45)-83( plays)-22( an)-8( important)-88( role)-69( in)-31( signal)-5( transduction,)-56( inhibition)-71( or)-6( upregulation)-19( of)-48( various)]TJ
0 -1.455 TD
[(immunological)-27( functions.)-56( Antibodies)-65( recognising)-75( a)-20( common)-33( epitope)-9( on)-81( all)-17( of)-48( the)-36( isoforms)-2( are)-44( termed)-43( CD45)-83( whilst)]TJ
0 -1.455 TD
[(those)-47( recognising)-75( only)-81( individual)-21( isoforms)-2( are)-44( termed)-43( CD45RA)-44( or)-6( CD45RO)-27( etc.)]TJ
/TT1 1 Tf
0 Tw 0 -1.909 TD
(Purification:)Tj
/TT0 1 Tf
-0.04 Tw 6.727 -0.091 Td
[(Was)-36( purified)-38( by)-40( Protein)-81( A)-36( and peptide)-90( affinity)-82( chromatography.)]TJ
/TT1 1 Tf
0 Tw -6.727 -2 Td
(Storage:)Tj
/TT0 1 Tf
-0.04 Tw 0 -1.455 TD
[(Prepared)-46( as)-29( lyophilized)-45( powder)-87( or)-6( liquid)-13( and shipped)-37( on)-81( ice.)-26( Store)-44( at)-50( -)-1(20\260C)-18( for)-52( one)-9( year.)-61( Protect)-73( from)-30( light.)]TJ
/TT1 1 Tf
0 Tw 0 -1.909 TD
(Reconstitution:)Tj
/TT0 1 Tf
-0.04 Tw 0 -1.455 TD
[(If)-36( the)-36( antibody)-25( is)-52( in)-31( liquid)-13( form,)-91( it)-73( is)-52( ready)-83( to)-32( use,)-76( no)-81( reconstitution)-78( needed.)]TJ
0 -2.909 TD
[(Reconstitution)-90( is)-52( only)-81( required)-62( for)-52( the)-36( lyophilized)-45( antibody.)-86( Please)-15( refer)-92( to)-32( the)-37( reconstitution)-78( instruction)-26( card)-10( in)]TJ
0 -1.455 TD
[(the)-36( package.)]TJ
/TT1 1 Tf
0 Tw 54.182 29.818 Td
(Size:)Tj
/TT0 1 Tf
-0.04 Tw 3 -0.091 Td
[(100ul)-29( or)-6( 100ug)-69( lyophilized)]TJ
/TT1 1 Tf
0 Tw -3 -2.818 Td
(Concentration:)Tj
/TT0 1 Tf
8.091 -0.091 Td
(1ug/uL)Tj
/TT1 1 Tf
-8.091 -2.818 Td
(Host:)Tj
/TT0 1 Tf
3.273 -0.091 Td
(Rabbit)Tj
/TT1 1 Tf
-3.273 -1.909 Td
(Reactivities:)Tj
0.2 scn
/TT0 1 Tf
6.6416 0 0 6.6416 482.2191 633.0815 Tm
(Mouse,)Tj
0 scn
/TT1 1 Tf
7.3058 0 0 7.3058 424.437 619.1341 Tm
(Application:)Tj
ET
q
10 36 575 780 re
W n
q 1 0 0 1 434.3994 601.5338 cm
0 0 m
0 1.328 -1.992 1.328 -1.992 0 c
-1.992 -1.328 0 -1.328 0 0 c
f
Q
Q
BT
/TT0 1 Tf
7.3058 0 0 7.3058 441.041 599.8734 Tm
[(FACS\(1:100)-73(-)-1(500\))]TJ
ET
q
10 36 575 780 re
W n
q 1 0 0 1 434.3994 590.9072 cm
0 0 m
0 1.328 -1.992 1.328 -1.992 0 c
-1.992 -1.328 0 -1.328 0 0 c
f
Q
Q
BT
/TT0 1 Tf
7.3058 0 0 7.3058 441.041 589.2468 Tm
[(IF\(1:100)-3(-)-1(500\))]TJ
ET
q
10 36 575 780 re
W n
q 1 0 0 1 434.3994 580.2806 cm
0 0 m
0 1.328 -1.992 1.328 -1.992 0 c
-1.992 -1.328 0 -1.328 0 0 c
f
Q
Q
BT
/TT0 1 Tf
-0.04 Tw 7.3058 0 0 7.3058 441.041 578.6202 Tm
[(Not)-1( yet)-6( tested)-8( in)-31( other)-43( applications.)]TJ
0 -1.455 TD
[(Optimal)-36( working)-62( dilutions)-48( must)-4( be)]TJ
0 -1.455 TD
[(determined)-86( by)-40( the)-36( end)-90( user.)]TJ
/TT1 1 Tf
-0.02 Tw -2.273 -3.818 Td
[(Antibody)-48( Type:)]TJ
/TT0 1 Tf
0 Tw 8.182 -0.091 Td
(Polyclonal)Tj
/TT1 1 Tf
-8.182 -1.909 Td
(Isotype:)Tj
0.2 scn
/TT0 1 Tf
6.6416 0 0 6.6416 467.6075 514.8607 Tm
(IgG)Tj
0 scn
/TT1 1 Tf
-0.02 Tw 7.3058 0 0 7.3058 424.437 500.9133 Tm
[(Molecular)-1( Weight:)]TJ
0.2 scn
/TT0 1 Tf
0 Tw 6.6416 0 0 6.6416 503.4723 500.9133 Tm
(141kDa)Tj
0 scn
/TT1 1 Tf
7.3058 0 0 7.3058 424.437 486.9659 Tm
(Preservatives:)Tj
0.2 scn
/TT0 1 Tf
-0.012 Tw 6.6416 0 0 6.6416 424.437 477.0035 Tm
[(10ug/uL)-59( )1(BSA)-54( )1(and)-64( )1(0.1%)-28( )1(NaN3.)]TJ
0 scn
0.021 Tw 5.9775 0 0 5.9775 424.437 449.7728 Tm
[(For)-20( )1(research)-16( )1(use)-25( )1(only.)-91( )1(CAUTION:)-13( )1(Not)-12( )1(for)-1( )1(human)-72( )1(or)]TJ
0 -1.333 TD
[(animal)-94( )1(therapeutic)-36( )1(or)-97( )1(diagnostic)-13( )1(use.)]TJ
ET
q
/GS0 gs
564.5375671 0 0 -0.6641693 15.3132935 706.8034821 cm
/Im1 Do
Q
BT
/TT0 1 Tf
0 Tw 10.6266 0 0 10.6266 21.2908 81.8272 Tm
( )Tj
ET
q
10 36 575 780 re
W n
/CS3 cs 0.302 0.306 0.333 scn
q 1 0 0 1 19.2983 691.5278 cm
0 0 m
0 1.771 -2.657 1.771 -2.657 0 c
-2.657 -1.771 0 -1.771 0 0 c
f
Q
Q
BT
/CS3 cs 0.302 0.306 0.333 scn
/TT1 1 Tf
-0.007 Tw 9.2983 0 0 9.2983 28.5965 688.8711 Tm
[(Rabbit)-50( Anti)-28(-)-69(CD45/B220)-57( Polyclonal)-4( Antibody,)-47( Cy7)-49( conjugated)]TJ
/CS0 cs 0 scn
/TT0 1 Tf
0 Tw 10.6266 0 0 10.6266 25.2757 374.7226 Tm
( )Tj
12.063 0 Td
( )Tj
12.125 0 Td
( )Tj
-24.188 -2.25 Td
( )Tj
12.063 0 Td
( )Tj
12.125 0 Td
( )Tj
-24.188 -2.25 Td
( )Tj
12.063 0 Td
( )Tj
12.125 0 Td
( )Tj
-0.04 Tw 7.3058 0 0 7.3058 26.604 295.0231 Tm
[(For)-30( full)-30( size)-82( images)-63( and description)-26( please)-13( click)-31( )]TJ
/CS3 cs 0 0.6 0.8 scn
0 Tw 6.6416 0 0 6.6416 180.6896 295.0231 Tm
(HERE)Tj
/CS0 cs 0 scn
7.3058 0 0 7.3058 197.2936 295.0231 Tm
(.)Tj
ET
q
/GS0 gs
0.6641693 0 0 -597.7456512 410.4896088 706.1392975 cm
/Im2 Do
Q
q
/GS0 gs
5.9774628 0 0 -40.5138702 569.888443 120.3485565 cm
/Im3 Do
Q
endstream
endobj
14 0 obj
<>
endobj
15 0 obj
(YBOfvcc#w)
endobj
25 0 obj
<>stream
Hy\E323#3
P̴,HLEK"+E+2VTD%EH# }wfwfvvc_3?{feޝ@HHHHHH*豘V]
zן)@-9.q2BÇEڂ8g "2vn>u2]/Yz \S@ 7.M&p?o9v 0'rKś-;(Au.J%% %&˶0>6`TxOzzo(VDY*AZp ËgAs^.㮌+2Ȱ$E['FC:OMCIVVDD3}`u߈buߨɴ4қԭV^V0XF ϓ@i|Y|.?i'3}Ŵ+ޘaa:
3g},F"kNɳՕx57,H)X7*v/Mո+(fWr=WӃJcߓtG16sPt:t"9G
if
3do\ˢ|c:1&<ЭWnPdq0IRgu~惘n9BWV2T6~}rs4h-D.sgV/n3;q@hThI*jTJqJK2c!QT7;60
5NoJݻ'rBP%ȍ4
P(/CJC1
9eڴ}5S{"wty@P5e*Zg~?S(Sɗ,ʽv 2[̋t_Z\d&}/2YϹO&y#
?P>,0P-
asds[U꼩\=T~)S>B,gk$7+j0?60<&uźg
A]_@en%Mȝ~5PSu$^2s0RSPw L9٦n9$vڣ=f#g 7,Oa
:ܾ.4+H!=MvF(G|YU
ITR)>@✧*[j5KoB{Kp,`姙$JO궒jvż@r3`w\A%jSx+>m;5ا@._1:T#q]wrTC8r:lU4P}~Y]XwJ~b:YQϗLP-X_ֻа2$ݥC=~P]VҘLhu?S'\C:7"4dD*%9 Ogfe\OLoTy5Qkj.84,: t:_YON3˃:O/r犁3t!Psbty{aETu7nMѶ f+^Y6zHic?R%+C,γL =ZJ1H+,x^
I!u2{5x_@LI6[w5LN5:xXoEgf9tu=yùw=aґza*҃K`驪eP/y*sσn3N{ME\8g: *fz#W??L