Search results for: elisa kits
#26137069 2015/7/2 Save this To Up
Survivin is not a promising serological maker for the diagnosis of hepatocellular carcinoma.Survivin expression in the serum of patients with hepatocellular carcinoma (HCC) and nonmalignant chronic liver diseases remain to be elucidated. The aims of the present study were to evaluate the diagnostic role of survivin in the serum of patients with HCC and identify which ELISA kit performed best in detecting the levels of serum survivin. In total, 80 patients were included in the present study, including 20 patients with HCC, 20 patients with liver cirrhosis, 20 patients with chronic hepatitis B virus infection and 20 healthy volunteers. The levels of survivin protein in the serum were detected using two different ELISA kits (R&D and Abnova). The positive ratios of serum survivin detected by the R&D ELISA kit in all the cases were 8.75% (7/80; median, 0 pg/ml; range, 0-39.8 pg/ml) and in HCC patients were 5% (1/20; median, 0 pg/ml; range, 0-39.8 pg/ml). For the same samples analyzed using the Abnova ELISA kit, the positive ratios of serum survivin in all the cases were 22.5% (18/80; median, 0 pg/ml; range, 0-553.5 pg/ml) and in HCC patients were 25% (5/20; median, 0 pg/ml; range, 0-93.5 pg/ml). The results obtained by the different ELISA kits demonstrated no statistically significant differences in the level of survivin between HCC patients and healthy controls. The correlation coefficient was 0.0064 (P=0.481) when analyzing the same serum samples with the different ELISA kits. In addition, the highest positive ratio of serum survivin was observed using the Abnova kit. A statistically significant difference in the results was observed between the R&D and Abnova kits. In general, the levels and positive ratios of serum survivin in the patients with HCC were significantly low. Furthermore, no difference was observed between HCC patients and controls in regard to the levels of serum survivin detected by the R&D and Abnova ELISA kits. In conclusion, survivin is unlikely to be a promising serological maker for the diagnosis of HCC.
1176 related Products with: Survivin is not a promising serological maker for the diagnosis of hepatocellular carcinoma.MOUSE ANTI BOVINE ROTAVIR MOUSE ANTI BORRELIA BURGD serologically defined col NATIVE HUMAN PROLACTIN, P 4-Amino-5-formylamino-3-i (3R,4S,5R,6S)-1-Aza-4-hyd RABBIT ANTI GSK3 BETA (pS Breast invasive ductal ca Hepatocellular carcinoma Hepatocellular carcinoma Hepatocellular carcinoma 10x ELISA WASH BUFFER, Pr
#26136723 2015/07/03 Save this To Up
Cerebrospinal Fluid P-Tau181P: Biomarker for Improved Differential Dementia Diagnosis.The goal of this study is to investigate the value of tau phosphorylated at threonine 181 (P-tau181P) in the Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarker panel for differential dementia diagnosis in autopsy confirmed AD and non-AD patients. The study population consisted of 140 autopsy confirmed AD and 77 autopsy confirmed non-AD dementia patients. CSF concentrations of amyloid-β peptide of 42 amino acids (Aβ1-42), total tau protein (T-tau), and P-tau181P were determined with single analyte ELISA-kits (INNOTEST(®), Fujirebio, Ghent, Belgium). Diagnostic accuracy was assessed through receiver operating characteristic (ROC) curve analyses to obtain area under the curve (AUC) values and to define optimal cutoff values to discriminate AD from pooled and individual non-AD groups. ROC curve analyses were only performed on biomarkers and ratios that differed significantly between the groups. Pairwise comparison of AUC values was performed by means of DeLong tests. The Aβ1-42/P-tau181P ratio (AUC = 0.770) performed significantly better than Aβ1-42 (AUC = 0.677, P = 0.004), T-tau (AUC = 0.592, P < 0.001), and Aβ1-42/T-tau (AUC = 0.678, P = 0.001), while P-tau181P (AUC = 0.720) performed significantly better than T-tau (AUC = 0.592, P < 0.001) to discriminate between AD and the pooled non-AD group. When comparing AD and the individual non-AD diagnoses, Aβ1-42/P-tau181P (AUC = 0.894) discriminated AD from frontotemporal dementia significantly better than Aβ1-42 (AUC = 0.776, P = 0.020) and T-tau (AUC = 0.746, P = 0.004), while P-tau181P/T-tau (AUC = 0.958) significantly improved the differentiation between AD and Creutzfeldt-Jakob disease as compared to Aβ1-42 (AUC = 0.688, P = 0.004), T-tau (AUC = 0.874, P = 0.040), and Aβ1-42/P-tau181P (AUC = 0.760, P = 0.003). In conclusion, this study demonstrates P-tau181P is an essential component of the AD CSF biomarker panel, and combined assessment of Aβ1-42, T-tau, and P-tau181P renders, to present date, the highest diagnostic power to discriminate between AD and non-AD dementias.
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#26134756 2015/7/2 Save this To Up
Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats.Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. Resveratrol (RSV) and N-acetylcysteine (NAC) are safe representatives of natural and synthetic antioxidants, respectively.
2463 related Products with: Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats.Liver disease spectrum ti Rat intestinal fatty acid Multiple diseases of live Fatty acid free heat sho Fatty acid free heat sho Fatty acid free heat sho Fatty acid free heat sho GST Inhibitor 2 (Ethacryn HBeAg test strip, Infecti Anti-HBeAg (HBeAb) test s Anti-HBcAg (HBcAb) test s HBV-5 panel test, sAg sAb
#26134400 2015/7/2 Save this To Up
Preoperative serum 8-hydroxydeoxyguanosine is associated with chemoresistance and is a powerful prognostic factor in endometrioid-type epithelial ovarian cancer.Oxidative stress is a widely seen phenomenon in several carcinomas. Increasing evidence also suggests that it has a significant role in the development of epithelial ovarian carcinoma (EOC). 8-Hydroxydeoxyguanosine (8-OHdG) is one of the main indicators of oxidative stress and increased expression of 8-OHdG has previously been seen in EOC. DJ-1 is an oncoprotein connected to oxidative stress regulation, but its role in ovarian cancer is not well known. We investigated redox status in different histotypes of EOC by measuring serum 8-OHdG and DJ-1 concentrations and their associations with known prognostic factors.
1060 related Products with: Preoperative serum 8-hydroxydeoxyguanosine is associated with chemoresistance and is a powerful prognostic factor in endometrioid-type epithelial ovarian cancer.Mouse Anti-Insulin-Like G Interleukin-34 IL34 (N-t Interleukin-34 IL34 anti MOUSE ANTI BOVINE ROTAVIR Anti AGO2 Human, Monoclon Anti AGO2 Mouse, Monoclon Anti AGO2 Human, Monoclon Anti AGO2 Mouse, Monoclon HIV1 integrase antibody, Human Serum Albumin antib Human Serum Albumin antib Bacillus anthracis (Anthr
#26131277 2015/07/01 Save this To Up
Association between serum carcinoembryonic antigen level and oxidative stress parameters among diabetic females.In this study we intended to determine serum level of the carcinoembryonic antigen (CEA) and to find out the correlation with oxidative stress parameters among diabetic female in comparison to control subjects.
1015 related Products with: Association between serum carcinoembryonic antigen level and oxidative stress parameters among diabetic females.OXI TEK (Oxidative Stress Anti CML Monoclonal Antib 8 Isoprostane oxidative s DIABETIC DISEASES-Glycate DIABETIC DISEASES Glycate Human Legionella pneumoph Bovine Androstenedione,AS Transcription factors: O Single Donor Human Diabet Human Carcinoembryonic An Mouse Anti-Human Carcinoe MAP-2 antigen
#26131235 2015/07/01 Save this To Up
Visfatin and ghrelin: can they be forthcoming biomarkers or new drug targets for asthma?Asthma represents chronic inflammation of the airways and is associated with bronchial hyperresponsiveness and reversible airway obstruction. A novel adipokine visfatin and an appetite-modulating hormone ghrelin play a role in several diseases related with inflammation. Although visfatin is a pro-inflammatory adipokine, ghrelin mainly exerts anti-inflammatory effects. However, very little is known about the role of visfatin and ghrelin in asthma. In the present study, we aimed to investigate the role of visfatin and ghrelin in asthma by evaluating their serum levels in asthmatic patients.
2382 related Products with: Visfatin and ghrelin: can they be forthcoming biomarkers or new drug targets for asthma?succinate-CoA ligase, GDP succinate-CoA ligase, ADP Glucose Assay With the La (5Z)-7-[(5-Acetyloxy-2-fo (5Z)-7-[(5-Acetyloxy-2-fo 6-Amino-1-benzyl-5-(N-for 6-Amino-1-benzyl-3-methyl RABBIT ANTI GSK3 BETA (pS Benzyl 2-Benzyloxy-5-form rac-N-Benzyl-N-[2-hydroxy Benzyl (2S,3S,5S)-2-Hexyl (7’-Benzyloxy-indolymet
#26118588 2015/6/29 Save this To Up
Clinical evaluation of dengue RNA, NS1 and IgM for diagnosis of dengue in Southern China.In 2014 a large outbreak of dengue occurred in Guangzhou, China. This outbreak prompted us to evaluate NS1 and RNA for the early diagnosis of acute dengue infection, in addition to the combination with IgM antibody. We aimed to find the differences of three assays about dengue diagnosis.
1026 related Products with: Clinical evaluation of dengue RNA, NS1 and IgM for diagnosis of dengue in Southern China.Recombinant Dengue Virus Recombinant Dengue Virus Recombinant Dengue Virus Recombinant Dengue Virus Recombinant Dengue Virus Recombinant Dengue Virus Recombinant Dengue Virus Recombinant Dengue Virus Recombinant Dengue Virus Dengue Virus IgM Dengue Virus General type Anti AGO2 Human, Monoclon
#26115171 2015/06/27 Save this To Up
Diarrheal and respiratory illness surveillance during US-RP Balikatan 2014.Diarrheal and respiratory illness surveillance was conducted during the 2014 Republic of the Philippines-U.S. Exercise Balikatan in the Philippines. Seven stool and three respiratory specimens that met the inclusion criteria were collected. Diarrhea stool specimens were tested with commercial enzyme-linked immunosorbent assay kits and real-time polymerase chain reaction (PCR) for 12 viral, bacterial, and protozoan pathogens. Campylobacter, enterotoxigenic Escherichia coli (ETEC), and enteropathogenic Escherichia coli (EPEC) were detected in four of seven (57%), two of seven (29%), and four of seven (57%) specimens, respectively. There were co-infections of EPEC and ETEC in two cases and EPEC and Campylobacter spp. in one case. Respiratory samples were tested using RT-PCR. One of three samples was positive for influenza B. Laboratory-based surveillance is important in determining causative agents for illnesses experienced by military personnel during deployment. Development of vaccines for enteric diseases should be expedited to mitigate their impact on operational readiness.
2170 related Products with: Diarrheal and respiratory illness surveillance during US-RP Balikatan 2014.RPL21 RPTPâ„¢ RPTPε RPMI 1640 without L Gln, RPMI 1640 without L‐Gln Androgen Receptor (Phosph Androgen Receptor (Phosph Goat Anti-Human RPGRIP1L Rabbit Anti-Human RPS6K1 Rabbit Anti-Human Androge Rabbit Anti-Human Androge Androgen Receptor (Ab 650
#26111949 2015/6/26 Save this To Up
A comparison of two commercially available ELISA methods for the quantification of human plasma heat shock protein 70 during rest and exercise stress.This study compared resting and exercise heat/hypoxic stress-induced levels of plasma extracellular heat shock protein 70 (eHSP70) in humans using two commercially available enzyme-linked immunosorbent assay (ELIS)A kits. EDTA plasma samples were collected from 21 males during two separate investigations. Participants in part A completed a 60-min treadmill run in the heat (HOT70; 33.0 ± 0.1 °C, 28.7 ± 0.8 %, n = 6) at 70 %
2757 related Products with: A comparison of two commercially available ELISA methods for the quantification of human plasma heat shock protein 70 during rest and exercise stress.Rabbit heat shock protein Rabbit heat shock protein Heat Shock Protein 70, hu Heat Shock Protein 70, hu Heat Shock Protein 70, hu Mouse Anti-Heat Shock Pro Heat Shock 70kDa Protein Heat Shock Protein 70 (H Heat Shock Protein 70 (H Bone Morphogenetic Protei Human Amyloid Beta Precur Human S100 Calcium Bindin
#26105582 2015/6/24 Save this To Up
Fenofibrate reduces inflammation in obese patients with or without type 2 diabetes mellitus via sirtuin 1/fetuin A axis.The aim of the current study is to investigate the effect of fenofibrate alone and in combination with pioglitazone on serum sirtuin 1 and fetuin A of obese patients with Type 2 Diabetes Mellitus (T2DM).
2335 related Products with: Fenofibrate reduces inflammation in obese patients with or without type 2 diabetes mellitus via sirtuin 1/fetuin A axis.Inflammation (Human) Anti Inflammation (Human) Anti Multi organ carcinoma tis Multi organ carcinoma tis High density (188 cases 2 High density (188 cases 2 Multiple organ cancer and Multiple organ cancer fro High density (208 cores), Multiple organ tumor tiss Multiple cancer (12 type) Multiple organ tumor with
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