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#33557983   2021/02/09 To Up

Economic impact of the use of the National Surgical Quality Improvement Program.

The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP®) is a validated, risk-adjusted database for improving the quality and security of surgical care. ACS NSQIP can help participating hospitals target areas that need improvement. The aim of this study was to systematically review the literature analyzing the economic impact of using NSQIP. This paper also provides an estimation of annual cost savings following the implementation of NSQIP and quality improvement (QI) activities in two hospitals in Quebec.
Alvine Fansi, Angela Ly, Julie Mayrand, Maggy Wassef, Aldanie Rho, Sylvie Beauchamp

1162 related Products with: Economic impact of the use of the National Surgical Quality Improvement Program.

1mg12000 IU100.00 ul1 ml1500 Units110

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#31899097   2019/12/30 To Up

Socioeconomic deprivation and blood lipids in first-episode psychosis patients with minimal antipsychotic exposure: Implications for cardiovascular risk.

The influence of socioeconomic deprivation on the cardiovascular health of patients with psychosis-spectrum disorders (PSD) has not been investigated despite the growing recognition of social factors as determinants of health, and the disproportionate rates of cardiovascular mortality observed in PSD. Discordant results have been documented when studying dyslipidemia -a core cardiovascular risk factor- in first-episode psychosis (FEP), before chronic exposure to antipsychotic medications. The objective of the present study is to determine the extent to which socioeconomic deprivation affects blood lipids in patients with FEP, and examine its implications for cardiovascular risk in PSD.
Franz Veru-Lesmes, Aldanie Rho, Ridha Joober, Srividya Iyer, Ashok Malla

1144 related Products with: Socioeconomic deprivation and blood lipids in first-episode psychosis patients with minimal antipsychotic exposure: Implications for cardiovascular risk.

250 mg 1 G 1 G 5 G 100 UG500 MG96 tests 100 G2 Pieces/Box

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#29661027   2018/04/16 To Up

Social Determinants of Health and Preclinical Glycemic Control in Newly Diagnosed First-Episode Psychosis Patients.

The abnormally high incidence of disorders of glucose metabolism (DGM) in psychotic-spectrum disorders (PSD) has often been attributed to the side effects of antipsychotics and unhealthy lifestyles. The influence of social determinants of health has been largely ignored, despite ample evidence linking social adversity with both PSD and DGM. The aim of this study is to examine the influence of well-established social determinants of health on preclinical levels of glycated hemoglobin (HbA1c) in a sample of first-episode psychosis (FEP) patients.
Franz Veru-Lesmes, Aldanie Rho, Suzanne King, Ridha Joober, Marita Pruessner, Ashok Malla, Srividya N Iyer

1579 related Products with: Social Determinants of Health and Preclinical Glycemic Control in Newly Diagnosed First-Episode Psychosis Patients.



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#29550056   // To Up

Corrigendum to "Therapeutic Effectiveness and Tolerability of Aripiprazole as Initial Choice of Treatment in First Episode Psychosis in an Early Intervention Service: A One-Year Outcome Study" [Schizophr. Res. 147, 120-125].


Ashok Malla, Sally Mustafa, Aldanie Rho, Sherezad Abadi, Martin Lepage, Ridha Joober

1697 related Products with: Corrigendum to "Therapeutic Effectiveness and Tolerability of Aripiprazole as Initial Choice of Treatment in First Episode Psychosis in an Early Intervention Service: A One-Year Outcome Study" [Schizophr. Res. 147, 120-125].

100 μg0.1ml (1mg/ml)96 tests100 μg900 tests

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#29372157   2017/12/18 To Up

Clinical experience of long-term use of dienogest after surgery for ovarian endometrioma.

Endometriosis is a common and recurring gynecologic disease which have afflicting females of reproductive age. We investigated the efficacy of long-term, post-operative use of dienogest for ovarian endometrioma.
Anjali Chandra, A Mi Rho, Kyungah Jeong, Taeri Yu, Ji Hyun Jeon, So Yun Park, Sa Ra Lee, Hye-Sung Moon, Hye Won Chung

2942 related Products with: Clinical experience of long-term use of dienogest after surgery for ovarian endometrioma.

100μg100μg100ug25 μg100μg

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#27157800   2016/05/04 To Up

Therapeutic effectiveness and tolerability of aripiprazole as initial choice of treatment in first episode psychosis in an early intervention service: A one-year outcome study.

Aripiprazole has been associated with a low prevalence of metabolic side effects as compared to other second generation antipsychotic (SGA) medications mostly in patients with long standing illness. The purpose of the present study was to assess specifically the effectiveness and safety of aripiprazole as a first choice for antipsychotic therapy for young patients presenting with a previously untreated first episode of a psychotic disorder (FEP).
Ashok Malla, Sally Mustafa, Aldanie Rho, Sherezad Abadi, Martin Lepage, Ridha Joober

2055 related Products with: Therapeutic effectiveness and tolerability of aripiprazole as initial choice of treatment in first episode psychosis in an early intervention service: A one-year outcome study.

100 μg48 samples100 μg100 μg900 tests100 μg

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#25921441   2015/04/25 To Up

Clinical and functional implications of a history of childhood ADHD in first-episode psychosis.

There is mounting evidence indicating that a childhood history of attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk for psychotic disorders, including schizophrenia. However, the implications of such a history on the symptomatic and functional outcomes of patients with psychotic disorders are still not well documented. This study examined the prevalence of childhood ADHD in patients with first episode psychosis (FEP) consecutively admitted to a specialized early intervention clinic covering a well-defined catchment area, and compared patients with and without a history of childhood ADHD on socio-demographic, clinical, and functional outcomes over a six to twelve months period. Out of 179 patients with FEP, 27 (15%) were treated for ADHD during childhood, consistent with previous literature indicating an association between childhood ADHD and psychosis. FEP patients with childhood history of ADHD had lower academic achievement, earlier onset of psychosis, and higher rates of childhood conduct and learning disorder. While the two groups had similar scores on psychopathology and functioning at baseline, patients with childhood ADHD showed significantly less improvement in positive and negative symptoms, as well as social and occupational functioning. These results strongly indicate that a history of childhood ADHD in FEP is more frequent than that reported in the general population and predictive of poorer clinical response to treatment. This emphasizes the need for actively screening for a history of ADHD in FEP patients and for treatments that are tailored for these patients.
Aldanie Rho, Alexandru Traicu, Martin Lepage, Srividya N Iyer, Ashok Malla, Ridha Joober

1985 related Products with: Clinical and functional implications of a history of childhood ADHD in first-episode psychosis.



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#24275585   2013/11/22 To Up

TCF4 gene polymorphism and cognitive performance in patients with first episode psychosis.

Single nucleotide polymorphisms in TCF4 gene have been consistently associated with schizophrenia in genome wide association studies, including the C allele of rs9960767. However, its exact role in modulating the schizophrenia phenotype is not known.
Ammar Albanna, Zia Choudhry, Philippe-Olivier Harvey, Ferid Fathalli, Clifford Cassidy, Sarojini M Sengupta, Srividya N Iyer, Aldanie Rho, Martin Lepage, Ashok Malla, Ridha Joober

1485 related Products with: TCF4 gene polymorphism and cognitive performance in patients with first episode psychosis.

96T5ug2ug300 units96T100 μg100 μg100ug Lyophilized

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#12065295   // To Up

Effects of bile acids on the muscle functions of guinea pig gallbladder.

Hydrophobic bile acids impair gallbladder emptying in vivo and inhibit gallbladder muscle contraction in response to CCK-8 in vitro. This study was aimed at determining the mechanisms of muscle cell dysfunction caused by bile acids in guinea pig gallbladders. Muscle cells were obtained by enzymatic digestion. Taurochenodeoxycholic acid (TCDC), a hydrophobic bile acid, caused a contraction of up to 15% and blocked CCK-induced contraction. Indomethacin abolished the TCDC-induced contraction. Hydrophilic bile acid tauroursodeoxycholic acid (TUDC) had no effect on muscle contraction but prevented the TCDC-induced contraction and its inhibition on CCK-induced contraction. Pretreatment with NADPH oxidase inhibitor PH2I, xanthine oxidase inhibitor allopurinol, and free-radical scavenger catalase also prevented TCDC-induced contraction and its inhibition of the CCK-induced contraction. TCDC caused H2O2 production, lipid peroxidation, and increased PGE2 synthesis and activities of catalase and SOD. These changes were significantly inhibited by pretreatment of PH2I or allopurinol. Inhibitors of cytosolic phospholipase A2 (cPLA2), protein kinase C (PKC), and mitogen-activating protein kinase (MAPK) also blocked the TCDC-induced contraction. It is concluded that hydrophobic bile acids cause muscle cell dysfunction by stimulating the formation of H2O2 via activation of NADPH and xanthine oxidase. H2O2 causes lipid peroxidation and activates cPLA2 to increase PGE2 production, which, in turn, stimulates the synthesis of free-radical scavengers through the PKC-MAPK pathway.
Zuo-Liang Xiao, Aloysius K Rho, Piero Biancani, Jose Behar

1855 related Products with: Effects of bile acids on the muscle functions of guinea pig gallbladder.

600 Tests / Kit 5 G430 Tests / Kit430 tests 25 ml Ready-to-use 25ml100ul500 ml250ug 6 ml Ready-to-use 100.00 ug

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