Search results for: 1-Acetyl-3-indoxyl-d4 C10H5D4NO2 CAS:
#38652440 2024/04/23 To Up
CRISPR-Cas13a-Triggered DNAzyme Signal Amplification-Based Colorimetric miRNA Detection Method and Its Application in Evaluating the Anxiety.
TNa Yan, Zhiwei Hu, Lingling Zhang
2437 related Products with: CRISPR-Cas13a-Triggered DNAzyme Signal Amplification-Based Colorimetric miRNA Detection Method and Its Application in Evaluating the Anxiety.
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#38652321 2024/04/23 To Up
Advances in miniature CRISPR-Cas proteins and their applications in gene editing.
The CRISPR-Cas system consists of Cas proteins and single-stranded RNAs that recruit Cas proteins and specifically target the nucleic acid. Some Cas proteins can accurately cleave the target nucleic acid under the guidance of the single-stranded RNAs. Due to its exceptionally high specificity, the CRISPR-Cas system is now widely used in various fields such as gene editing, transcription regulation, and molecular diagnosis. However, the huge size of the most frequently utilized Cas proteins (Cas9, Cas12a, and Cas13, which contain 950-1,400 amino acids) can limit their applicability, especially in eukaryotic gene editing, where larger Cas proteins are difficult to deliver into the target cells. Recently discovered miniature CRISPR-Cas proteins, consisting of only 400 to 800 amino acids, offer the possibility of overcoming this limitation. This article systematically reviews the latest research progress of several miniature CRISPR-Cas proteins (Cas12f, Cas12j, Cas12k, and Cas12m) and their practical applications in the field of gene editing.Huimin Wu, Yixiang Sun, Yimai Wang, Liqiang Luo, Yizhi Song
1753 related Products with: Advances in miniature CRISPR-Cas proteins and their applications in gene editing.
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#38652294 2024/04/23 To Up
Plant diversity increases spatial stability of aboveground productivity in alpine grasslands.
Plant diversity can significantly affect the grassland productivity and its stability. However, it remains unclear how plant diversity affects the spatial stability of natural grassland productivity, especially in alpine regions that are sensitive to climate change. We analyzed the interaction between plant (species richness and productivity, etc.) and climatic factors (precipitation, temperature, and moisture index, etc.) of alpine natural grassland on the Qinghai-Tibetan Plateau. In addition, we tested the relationship between plant diversity and spatial stability of grassland productivity. Results showed that an increase in plant diversity significantly enhanced community productivity and its standard deviation, while reducing the coefficient of variation in productivity. The influence of plant diversity on productivity and the reciprocal of productivity variability coefficient was not affected by vegetation types. The absolute values of the regression slopes between climate factors and productivity in alpine meadow communities with higher plant diversity were smaller than those in alpine meadow communities with lower plant diversity. In other words, alpine meadow communities with higher plant diversity exhibited a weaker response to climatic factors in terms of productivity, whereas those with lower plant diversity showed a stronger response. Our results indicate that high plant diversity buffers the impact of ambient pressure (e.g., precipitation, temperature) on alpine meadow productivity, and significantly enhanced the spatial stability of grassland productivity. This finding provides a theoretical basis for maintaining the stability of grassland ecosystems and scientifically managing alpine grasslands under the continuous climate change.Zeng Cui, Jian Sun, Gao-Lin Wu
1384 related Products with: Plant diversity increases spatial stability of aboveground productivity in alpine grasslands.
4/120 Packing /sleeve/bo4/120 Packing /sleeve/bo96tests4/120 Packing /sleeve/bo1 Set1 Set5 mg 0.1 mgRelated Pathways
#38652293 2024/04/23 To Up
Intraspecific alternative phenotypes contribute to variation in species' strategies for growth.
Ecologists have historically sought to identify the mechanisms underlying the maintenance of local species diversity. High-dimensional trait-based relationships, such as alternative phenotypes, have been hypothesized as important for maintaining species diversity such that phenotypically dissimilar individuals compete less for resources but have similar performance in a given environment. The presence of alternative phenotypes has primarily been investigated at the community level, despite the importance of intraspecific variation to diversity maintenance. The aims of this research are to (1) determine the presence or absence of intraspecific alternative phenotypes in three species of tropical tree seedlings, (2) investigate if these different species use the same alternative phenotypes for growth success, and (3) evaluate how findings align with species co-occurrence patterns. We model species-specific relative growth rate with individual-level measurements of leaf mass per area (LMA) and root mass fraction (RMF), environmental data, and their interactions. We find that two of the three species have intraspecific alternative phenotypes, with individuals within species having different functional forms leading to similar growth. Interestingly, individuals within these species use the same trait combinations, high LMA low RMF and low LMA high RMF, in high soil nutrient environments to acquire resources for higher growth. This similarity among species in intraspecific alternative phenotypes and variables that contribute most to growth may lead to their negative spatial co-occurrence. Overall, we find that multiple traits or interactions between traits and the environment drive species-specific strategies for growth, but that individuals within species leverage this multi-dimensionality in different ways for growth success.Samantha J Worthy, María N Umaña, Caicai Zhang, Luxiang Lin, Min Cao, Nathan G Swenson
2078 related Products with: Intraspecific alternative phenotypes contribute to variation in species' strategies for growth.
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#38652189 2024/04/23 To Up
Siderophore-producing bacteria from Spitsbergen soils-novel agents assisted in bioremediation of the metal-polluted soils.
SMałgorzata Majewska, Anna Słomka, Agnieszka Hanaka
1194 related Products with: Siderophore-producing bacteria from Spitsbergen soils-novel agents assisted in bioremediation of the metal-polluted soils.
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#38652094 2024/04/23 To Up
Sulfonic Acid Functionalized Ionic Liquids for Defect Passivation via Molecular Interactions for High-Quality Perovskite Films and Stable Solar Cells.
TJunhui Fang, Liang Wang, Zhaoyang Chen, Shuai Wang, Lin Yuan, Aamir Saeed, Iqbal Hussain, Jianwei Zhao, Ruixia Liu, Qingqing Miao
2249 related Products with: Sulfonic Acid Functionalized Ionic Liquids for Defect Passivation via Molecular Interactions for High-Quality Perovskite Films and Stable Solar Cells.
1 G 500 G 1 G20 ug10 mg 1 G25 g 1 G 2x5L5 g 100 GRelated Pathways
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#38651920 2024/04/23 To Up
Biomechanical effects of clear aligner with different shape design at extraction space area during anterior teeth retraction.
This study aimed to investigate the biomechanical effects of clear aligner (CA) with different shape designs at extraction space (CAES) area during space closing.Bochun Mao, Yajing Tian, Yujia Xiao, Jiayi Liu, Dawei Liu, Jing Li, Yanheng Zhou
1794 related Products with: Biomechanical effects of clear aligner with different shape design at extraction space area during anterior teeth retraction.
5100ug Lyophilized10 ug100ul100μl20 ul100 extractions100ug 50 MG100ul100 extractions1 mlRelated Pathways
#38651836 2024/04/23 To Up
Machine Learning for Experimental Reactivity of a Set of Metal Clusters toward C-H Activation.
Understanding the mechanisms of C-H activation of alkanes is a very important research topic. The reactions of metal clusters with alkanes have been extensively studied to reveal the electronic features governing C-H activation, while the experimental cluster reactivity was qualitatively interpreted case by case in the literature. Herein, we prepared and mass-selected over 100 rhodium-based clusters (RhVO and RhCoO) to react with light alkanes, enabling the determination of reaction rate constants spanning six orders of magnitude. A satisfactory model being able to quantitatively describe the rate data in terms of multiple cluster electronic features (average electron occupancy of valence s orbitals, the minimum natural charge on the metal atom, cluster polarizability, and energy gap involved in the agostic interaction) has been constructed through a machine learning approach. This study demonstrates that the general mechanisms governing the very important process of C-H activation by diverse metal centers can be discovered by interpreting experimental data with artificial intelligence.Xi-Guan Zhao, Qi Yang, Ying Xu, Qing-Yu Liu, Zi-Yu Li, Xiao-Xiao Liu, Yan-Xia Zhao, Sheng-Gui He
1305 related Products with: Machine Learning for Experimental Reactivity of a Set of Metal Clusters toward C-H Activation.
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#38651620 2024/04/23 To Up
Acceptor-Reactivity-Controlled Stereoconvergent Synthesis and Immunological Activity of a Unique Pentasaccharide from the Cell Wall Polysaccharide of Cutibacterium acnes C7.
BTianhui Hao, Ke Feng, Hongzhen Jin, Jiawei Li, Chenkai Zhou, Xingbang Liu, Wei Zhao, Fan Yu, Tiehai Li
1470 related Products with: Acceptor-Reactivity-Controlled Stereoconvergent Synthesis and Immunological Activity of a Unique Pentasaccharide from the Cell Wall Polysaccharide of Cutibacterium acnes C7.
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#38651538 2024/04/23 To Up
A wafer scale thin film of ultra-small ScO nanocrystals on a 2D COF with high rigidity.
Scandium oxide (ScO) has a wide range of applications in metallurgy, chemical industry, electronics and many other high-tech fields. However, most ScO materials exist in the powder or bulk form, while nanostructured ScO has rarely been reported as there is a lack of a common method to control its dimensionality, hindering the understanding of new properties and potential applications of nano-ScO materials. In this paper, we establish a procedure to synthesize a two-dimensional (2D) ScO-covalent organic framework (COF) composite film where the crystal size of ScO domains is as small as ∼3 nm. The composite film is prepared by a Schiff base condensation reaction at the sharp -pentane/water interface using a combination of surfactant-monolayer-assisted interfacial synthesis and laminar assembly polymerization methods. Then the conditions of nucleation and uniform film formation of the 2D ScO/COF are explored further. Meanwhile, an atomic force microscopy indentation test shows that the material has a high Young's modulus of 89.1 ± 3.8 GPa, which is much higher than those of the majority of reported 2D polymer materials. We further extended this synthesis method to the preparation of YbO (ytterbium oxide) and/or ErO (erbium oxide)-incorporated 2D COF composite films, verifying the universality of this strategy. This work provides an opportunity to vary the dimensionality of many kinds of metal oxides and explore the potential applications of low-dimensional ScO materials.Xin Guan, Xiaohui Xu, Zhongliang Yu, Junjie Xiong, Yanhong Chang, Bowen Liu, Bin Wang
1816 related Products with: A wafer scale thin film of ultra-small ScO nanocrystals on a 2D COF with high rigidity.
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