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#33652371   2021/02/12 To Up

Paradoxical sensory reactivity induced by functional disconnection in a robot model of neurodevelopmental disorder.

Neurodevelopmental disorders are characterized by heterogeneous and non-specific nature of their clinical symptoms. In particular, hyper- and hypo-reactivity to sensory stimuli are diagnostic features of autism spectrum disorder and are reported across many neurodevelopmental disorders. However, computational mechanisms underlying the unusual paradoxical behaviors remain unclear. In this study, using a robot controlled by a hierarchical recurrent neural network model with predictive processing and learning mechanism, we simulated how functional disconnection altered the learning process and subsequent behavioral reactivity to environmental change. The results show that, through the learning process, long-range functional disconnection between distinct network levels could simultaneously lower the precision of sensory information and higher-level prediction. The alteration caused a robot to exhibit sensory-dominated and sensory-ignoring behaviors ascribed to sensory hyper- and hypo-reactivity, respectively. As long-range functional disconnection became more severe, a frequency shift from hyporeactivity to hyperreactivity was observed, paralleling an early sign of autism spectrum disorder. Furthermore, local functional disconnection at the level of sensory processing similarly induced hyporeactivity due to low sensory precision. These findings suggest a computational explanation for paradoxical sensory behaviors in neurodevelopmental disorders, such as coexisting hyper- and hypo-reactivity to sensory stimulus. A neurorobotics approach may be useful for bridging various levels of understanding in neurodevelopmental disorders and providing insights into mechanisms underlying complex clinical symptoms.
Hayato Idei, Shingo Murata, Yuichi Yamashita, Tetsuya Ogata

1907 related Products with: Paradoxical sensory reactivity induced by functional disconnection in a robot model of neurodevelopmental disorder.

1 Product tipe: Instrumen100ug100ug Lyophilized100ug Lyophilized50ul100ug100ug Lyophilized96 assays100ug Lyophilized100 ul100ug100ug Lyophilized

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#33652370   2021/02/17 To Up

Self-augmentation: Generalizing deep networks to unseen classes for few-shot learning.

Few-shot learning aims to classify unseen classes with a few training examples. While recent works have shown that standard mini-batch training with carefully designed training strategies can improve generalization ability for unseen classes, well-known problems in deep networks such as memorizing training statistics have been less explored for few-shot learning. To tackle this issue, we propose self-augmentation that consolidates self-mix and self-distillation. Specifically, we propose a regional dropout technique called self-mix, in which a patch of an image is substituted into other values in the same image. With this dropout effect, we show that the generalization ability of deep networks can be improved as it prevents us from learning specific structures of a dataset. Then, we employ a backbone network that has auxiliary branches with its own classifier to enforce knowledge sharing. This sharing of knowledge forces each branch to learn diverse optimal points during training. Additionally, we present a local representation learner to further exploit a few training examples of unseen classes by generating fake queries and novel weights. Experimental results show that the proposed method outperforms the state-of-the-art methods for prevalent few-shot benchmarks and improves the generalization ability.
Jin-Woo Seo, Hong-Gyu Jung, Seong-Whan Lee

1483 related Products with: Self-augmentation: Generalizing deep networks to unseen classes for few-shot learning.

1000 ml 96 Tests n1 mg1 module1 g1 mg1.00 flask1 mg480/kit

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#33652348   2021/02/27 To Up

Regulatory T cells in autoimmune hepatitis: Un updated overview.

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Maria Serena Longhi, Giorgina Mieli-Vergani, Diego Vergani

1272 related Products with: Regulatory T cells in autoimmune hepatitis: Un updated overview.

50000 Units110 Inserts of 96 Tips/Uni96 tests96 tests

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#33652345   2021/02/27 To Up

Serum Albumin, Body Mass Index, and Preceding Xa and P2Y12 Inhibitors Predict Prognosis of Recurrent Ischemic Stroke.

A third to half of recurrent stroke occur while on antiplatelet therapy, but no study has explored factors relating to prognosis of recurrent ischemic stroke. This study aimed to clarify the risk factors to determine the clinical outcome of recurrent ischemic stroke.
Ryusei Kiboshi, Sousuke Satoh, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Norifumi Metoki, Tomohiro Osanai

2071 related Products with: Serum Albumin, Body Mass Index, and Preceding Xa and P2Y12 Inhibitors Predict Prognosis of Recurrent Ischemic Stroke.

96T100 mg50mg10 mg50ul10gm200ul100 μg50 mg200ul200ug

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#33652328   2021/02/24 To Up

Venous thromboembolism in Asia and worldwide: Emerging insights from GARFIELD-VTE.

Although epidemiological studies report a lower risk of venous thromboembolism (VTE) than in the Western world, VTE rates in Asia may be underestimated. Furthermore, it is uncertain whether VTE outcomes differ in Asia and the rest of the world (ROW).
Pantep Angchaisuksiri, Shinya Goto, Alfredo E Farjat, Henrik Fryk, Soo-Mee Bang, Chern-En Chiang, Zhi-Cheng Jing, Katsuhiro Kondo, Jameela Sathar, Eric Tse, Sithakom Phusanti, Gloria Kayani, Jeffrey I Weitz, Walter Ageno, Samuel Z Goldhaber, Ajay K Kakkar

2777 related Products with: Venous thromboembolism in Asia and worldwide: Emerging insights from GARFIELD-VTE.

1 Set50 ul96T16-22 Sample Kit100 μg100 μg100 μg

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#33652323   2021/02/20 To Up

Risk assessment of potential thaw settlement hazard in the permafrost regions of Qinghai-Tibet Plateau.

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Jie Ni, Tonghua Wu, Xiaofan Zhu, Xiaodong Wu, Qiangqiang Pang, Defu Zou, Jie Chen, Ren Li, Guojie Hu, Yizhen Du, Junming Hao, Xiangfei Li, Yongping Qiao

2538 related Products with: Risk assessment of potential thaw settlement hazard in the permafrost regions of Qinghai-Tibet Plateau.

1 5 G1 mg

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#33652322   2021/02/19 To Up

Long-term response of marine benthic fauna to thin-layer capping with powdered activated carbon in the Grenland fjords, Norway.

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Hilde C Trannum, Caroline Raymond, Rita Næss, Gunhild Borgersen, Jonas S Gunnarsson, Morten T Schaanning

2214 related Products with: Long-term response of marine benthic fauna to thin-layer capping with powdered activated carbon in the Grenland fjords, Norway.

100 μg1 mg 0.1 mg 100 μg100 μg100 μg

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#33652318   2021/02/16 To Up

Temporal variability in the impacts of particulate matter on crop yields on the North China Plain.

The North China Plain (NCP) is a major agricultural region, producing 45% of China's maize. It is also vital to the Chinese economy, encompassing the Beijing-Tianjin-Hebei megacity region. Anthropogenic factors increasingly impact crop yields on the NCP, and globally. Particulate matter (PM) pollution is a significant problem in this region, where annual average PM concentrations over three times the Chinese national air quality standard were recorded for the Beijing-Tianjin-Hebei megacity region between 2013 and 18. PM absorbs light, reducing total shortwave radiation (SW), thereby limiting plant productivity. However, PM also scatters incoming SW, increasing the diffuse fraction, which has been shown to increase growth and biomass assimilation. The Joint UK Land Environment Simulator (JULES) crop model was used to assess the net impact of these competing changes in light on NCP maize yields. In contrast to some previous analyses, we find that PM-associated decreases in SW outweigh any positive impact on yield from an increasing proportion of diffuse radiation. Furthermore, carbon allocation to different portions of the growing cropchanges during the development cycle. We find significant differences between the effect on final yield of identical changes to diffuse fraction and total SW occurring during different development stages. The greatest simulated yield gains from increased SW and reduced diffuse fraction, consistent with reductions in PM, are observed during the early reproductive stage of development (July-August), when the simulated gain of yield is as much as 12.9% more than in other periods. To further assess the impact of PM-linked changes in SW and diffuse fraction on NCP crop yields, radiation profiles from different city regions were then applied across the NCP. The changes in SW associated with these city regions could increase maize yields across China by ~8 Mt. This would completely offset China's annual maize imports, increasing both national and global food security.
Michael C Wolffe, Oliver Wild, Stephen P Long, Kirsti Ashworth

2058 related Products with: Temporal variability in the impacts of particulate matter on crop yields on the North China Plain.

1100ug200 units 2 ml

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