Search results for: IL-21, human recombinant
#38287796 // To Up
SIRT6 Reduces Rheumatoid Arthritis Injury by Inhibiting MyD88-ERK Signaling Pathway.
Rheumatoid arthritis (RA) is an autoimmune disease characterized by destruction of synovial joints, abnormal immune responses and chronic inflammatory manifestations, which seriously affects patients' well-being. We explored this study to ascertain the effect and mechanism of silent information regulator 6 (SIRT6) on RA.Xiaolong Yu, Zihan Jin, Faisal Raza, Ping Zhang, Jiabiao Wu, Min Ren, Jiapeng Wang, Jing Xi
1804 related Products with: SIRT6 Reduces Rheumatoid Arthritis Injury by Inhibiting MyD88-ERK Signaling Pathway.
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#38130396 2023/12/07 To Up
Exercise improves intestinal IgA production by T-dependent cell pathway in adults but not in aged mice.
Hypermutated high-affinity immunoglobulin A (IgA), neutralizes toxins and drives the diversification of bacteria communities to maintain intestinal homeostasis although the mechanism underlies the impact of moderate aerobic exercise (MAE) on the IgA-generation via T-dependent (TD) is not fully know. Therefore, the aim of this study was to determine the effect of long-time MAE on the production of IgA through the TD pathway in Peyer´s patches of the small intestine from aged mice.Angel Joel Hernández-Urbán, Maria Elisa Drago-Serrano, Andrea Cruz-Baquero, Ana Lilia García-Hernández, Ivonne Maciel Arciniega-Martínez, Judith Pacheco-Yépez, Fabiola Guzmán-Mejía, Marycarmen Godínez-Victoria
2796 related Products with: Exercise improves intestinal IgA production by T-dependent cell pathway in adults but not in aged mice.
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#37958995 2023/11/06 To Up
Persistent Hypogammaglobulinemia after Receiving Rituximab Post-HSCT Is Not Caused by an Intrinsic B Cell Defect.
ILisa M Ott de Bruin, Ingrid Pico-Knijnenburg, Monique M van Ostaijen-Ten Dam, Thomas J Weitering, Dagmar Berghuis, Robbert G M Bredius, Arjan C Lankester, Mirjam van der Burg
1032 related Products with: Persistent Hypogammaglobulinemia after Receiving Rituximab Post-HSCT Is Not Caused by an Intrinsic B Cell Defect.
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#37588597 2023/07/27 To Up
Phorbol-12-myristate-13-acetate is a potent enhancer of B cells with a granzyme B regulatory phenotype.
The infusion of -generated regulatory B cells may represent a promising novel therapeutic approach for a variety of autoimmune and hyperinflammatory conditions including graft-versus-host disease.Johanna Veh, Charlotte Mangold, Anja Felsen, Carolin Ludwig, Lisa Gerstner, Peter Reinhardt, Hubert Schrezenmeier, Dorit Fabricius, Bernd Jahrsdörfer
2611 related Products with: Phorbol-12-myristate-13-acetate is a potent enhancer of B cells with a granzyme B regulatory phenotype.
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#37006245 2023/03/17 To Up
Deficient leptin receptor signaling in T cells of human SLE.
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease mainly mediated by IgG autoantibody. While follicular helper T (Tfh) cells are crucial for supporting IgG autoantibody generation in human SLE, underlying mechanisms for Tfh cell mal-differentiation remain unclear.Ting Liu, Ming Zheng, Li Jia, Mingyuan Wang, Longhai Tang, Zhenke Wen, Miaojia Zhang, Fenghong Yuan
2662 related Products with: Deficient leptin receptor signaling in T cells of human SLE.
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#36574614 // To Up
Tumor-Associated CD19+CD39- B Regulatory Cells Deregulate Class-Switch Recombination to Suppress Antibody Responses.
BSubhadip Pati, Sumon Mukherjee, Saikat Dutta, Aharna Guin, Dia Roy, Sayantan Bose, Silpita Paul, Sudipto Saha, Sankar Bhattacharyya, Pratyush Datta, Jayati Chakraborty, Diptendra K Sarkar, Gaurisankar Sa
1244 related Products with: Tumor-Associated CD19+CD39- B Regulatory Cells Deregulate Class-Switch Recombination to Suppress Antibody Responses.
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#36443294 2022/11/28 To Up
Low-dose IL-2 reduces IL-21 T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes.
DJia-Yuan Zhang, Fiona Hamey, Dominik Trzupek, Marius Mickunas, Mercede Lee, Leila Godfrey, Jennie H M Yang, Marcin L Pekalski, Jane Kennet, Frank Waldron-Lynch, Mark L Evans, Timothy I M Tree, Linda S Wicker, John A Todd, Ricardo C Ferreira
1649 related Products with: Low-dose IL-2 reduces IL-21 T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes.
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#36159836 2022/09/08 To Up
Local Immunoglobulin E in nasal polyps: Role and modulation.
IYang Shen, Nan Zhang, Yucheng Yang, Suling Hong, Claus Bachert
1099 related Products with: Local Immunoglobulin E in nasal polyps: Role and modulation.
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#35679246 2022/06/09 To Up
Immunological investigation of a multiepitope peptide vaccine candidate based on main proteins of SARS-CoV-2 pathogen.
MNiloofar Khairkhah, Azam Bolhassani, Elnaz Agi, Ali Namvar, Arash Nikyar
2489 related Products with: Immunological investigation of a multiepitope peptide vaccine candidate based on main proteins of SARS-CoV-2 pathogen.
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#35648273 2022/06/01 To Up
Impact of IL-21-associated peripheral and brain crosstalk on the Alzheimer's disease neuropathology.
ASudhanshu Agrawal, Janet E Baulch, Shreya Madan, Seher Salah, Samantha N Cheeks, Robert P Krattli, Veedamali S Subramanian, Munjal M Acharya, Anshu Agrawal
1082 related Products with: Impact of IL-21-associated peripheral and brain crosstalk on the Alzheimer's disease neuropathology.
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