Search results for: 5-{[2-(6-Amino-9H-purin-9-yl)ethyl]amino}-1-pentanol C12H20N6O CAS: 686301-48-4
#38648296 2024/04/22 To Up
Polyphenol-Assisted Biomineralization of Metal-Organic Framework Nanoparticles for Precision Delivery of Therapeutic Proteins to Cancer Cells.
TTianli Luo, Qizhen Zheng, Ji Liu, Rui Yao, Ming Wang
2862 related Products with: Polyphenol-Assisted Biomineralization of Metal-Organic Framework Nanoparticles for Precision Delivery of Therapeutic Proteins to Cancer Cells.
501mg101mg1 mg1001010021.00 flaskRelated Pathways
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#38648198 2024/04/22 To Up
The impact of phage and phage resistance on microbial community dynamics.
WEllinor O Alseth, Rafael Custodio, Sarah A Sundius, Rachel A Kuske, Sam P Brown, Edze R Westra
2272 related Products with: The impact of phage and phage resistance on microbial community dynamics.
0.25 mL100ug100ug 6 ml 100 mg25 mg10 25 MGRelated Pathways
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#38648173 2024/04/22 To Up
How to use CRISPR/Cas9 in plants - from target site selection to DNA repair.
A tool for precise, target-specific, efficient and affordable genome editing, it is a dream for many researchers, from those who do basic research to those who use it for applied research. Since 2012, we have the tool that almost fulfils such requirements; it is based on CRISPR/Cas systems. However, even CRISPR/Cas has limitations and obstacles that might surprise its users. In this review, we focus on the most frequently used variant, CRISPR/Cas9 from Streptococcus pyogenes, and highlight the key factors affecting its mutagenesis outcomes. Firstly, factors affecting the CRISPR/Cas9 activity, such as the effect of the target sequence, chromatin state or Cas9 variant, and how long it remains in place after cleavage. Secondly, factors affecting the follow-up DNA repair mechanisms include mostly the cell type and cell cycle phase, but also, for example, the type of DNA ends produced by Cas9 cleavage (blunt/staggered). Moreover, we note some differences between using CRISPR/Cas9 in plants, yeasts and animals, as knowledge from individual kingdoms is not fully transferable. Awareness of these factors can increase the likelihood of achieving the expected results of plant genome editing, for which we provide detailed guidelines.Adéla Přibylová, Lukáš Fischer
1388 related Products with: How to use CRISPR/Cas9 in plants - from target site selection to DNA repair.
100 0.1ml (1.3mg/ml)100 1 mg500 gm.10 1 mgRelated Pathways
#38647965 2023/09/15 To Up
Thermophilic Moorella thermoacetica as a platform microorganism for C1 gas utilization: physiology, engineering, and applications.
IDechen Jia, Wangshuying Deng, Peng Hu, Weihong Jiang, Yang Gu
1135 related Products with: Thermophilic Moorella thermoacetica as a platform microorganism for C1 gas utilization: physiology, engineering, and applications.
10 mg250 ml5 g0.2 mg10 mg0.1 mg25 mg10 mg1 mg1 LITRE96 Tests0.5 mgRelated Pathways
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#38647893 2022/07/30 To Up
Production of free fatty acids from various carbon sources by Ogataea polymorpha.
EYunxia Li, XiaoXin Zhai, Wei Yu, Dao Feng, Aamer Ali Shah, Jiaoqi Gao, Yongjin J Zhou
1570 related Products with: Production of free fatty acids from various carbon sources by Ogataea polymorpha.
1,000 tests100tests1001KG500gm1kg100gm500g50gmRelated Pathways
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#38647822 2022/05/26 To Up
Microbial synthesis of long-chain α-alkenes from methanol by engineering Pichia pastoris.
�Peng Cai, Yunxia Li, Xiaoxin Zhai, Lun Yao, Xiaojun Ma, Lingyun Jia, Yongjin J Zhou
1525 related Products with: Microbial synthesis of long-chain α-alkenes from methanol by engineering Pichia pastoris.
1 mg100 µg1 mL100ug100ug6 ml100ug Lyophilized500 1mg2 mg100.00 ug0.5 mgRelated Pathways
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#38647771 2022/10/22 To Up
Combinatorial strategies for production improvement of anti-tuberculosis antibiotics ilamycins E/E from deep sea-derived Streptomyces atratus SCSIO ZH16 ΔilaR.
Ilamycins E/E are novel cyclic heptapeptides from Streptomyces atratus SCSIO ZH16, which have the MIC value of 9.8 nM against Mycobacterium tuberculosis H37Rv. However, the lower fermentative titer of ilamycins E/E cut off further development for novel anti-TB lead drugs. In order to break the obstacle, the combinatorial strategy of medium optimization, fermentative parameters optimization, exogenous addition of metal ions, precursors, and surfactants was developed to promoted the production of ilamycins E/E. Addition of 1 mM ZnCl at 0 h, 1 g/L tyrosine at 96 h, and 2 g/L shikimic acid at 48 h increased the production of ilamycins E/E from 13.51 to 762.50 ± 23.15, 721.39 ± 19.13, and 693.83 ± 16.86 mg/L, respectively. qRT-PCR results showed that the transcription levels of key genes in Embden-Meyerhof-Parnas pathway, hexose phosphate shunt pathway, and shikimic acid pathway were upregulated. In addition, the production of ilamycins E/E reached 790.34 mg/L in a 5-L bioreactor by combinatorial strategy. Combinatorial strategies were used for improving ilamycins E/E production in S. atratus ΔilaR and provided a sufficient basis on further clinic development.Yunfei Zhu, Gaofan Zheng, Xiujuan Xin, Junying Ma, Jianhua Ju, Faliang An
1462 related Products with: Combinatorial strategies for production improvement of anti-tuberculosis antibiotics ilamycins E/E from deep sea-derived Streptomyces atratus SCSIO ZH16 ΔilaR.
1 mg100μg0.1ml (1mg/ml)500 500 500 μg100ug100ug Lyophilized100ug1 mL100ug Lyophilized100μgRelated Pathways
#38647747 2022/05/18 To Up
A facile and robust T7-promoter-based high-expression of heterologous proteins in Bacillus subtilis.
TJing Ye, Yunjie Li, Yuqing Bai, Ting Zhang, Wei Jiang, Ting Shi, Zijian Wu, Yi-Heng P Job Zhang
2541 related Products with: A facile and robust T7-promoter-based high-expression of heterologous proteins in Bacillus subtilis.
50 25mg400TestsRelated Pathways
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