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#35537355   2022/05/07 To Up

Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression.

Atopic asthma and allergic rhinitis are common chronic inflammatory diseases affecting lower airways and nasal mucosa, respectively. Several reports demonstrated frequent co-occurrence of these two diseases, however, the exact molecular mechanism has not been described. The present study aimed to investigate if small non-coding RNA might be responsible for the co-occurrence of asthma and allergic rhinitis in an animal model of allergic airway inflammation.
Wojciech Langwiński, Dawid Szczepankiewicz, Beata Narożna, John Stegmayr, Darcy Wagner, Hani Alsafadi, Sandra Lindstedt, Zuzanna Stachowiak, Joanna Nowakowska, Marek Skrzypski, Aleksandra Szczepankiewicz

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