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#36753024 
2023/02/08
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Translocations and Gene Fusions in Sinonasal Malignancies.
During the past few years there has been an expansion in our understanding of gene fusions and translocations involved in cancer of the sinonasal tract. Here we review the downstream biologic effects, clinical characteristics, and pathologic features of these tumors. The molecular consequences and neo-antigens resulting from these chromosomal aberrations are considered and targets for current and future clinical trials discussed.Riley Larkin, Mario A Hermsen, Nyall R London