Alternate Names: B-TCGF, CSIF, TGIF

Interleukin 10 (IL-10) is an anti-inflammatory cytokine mainly produced by macrophages and Th2cells. IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including, IFN-γ, TNF-α, IL-2, and IL-3, IL-4, and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells. While human IL-10 can act on murine cells, murineIL-10 cannot act on human cells. Recombinant human IL-10 is a non-glycosylated protein, containing 161 amino acids and having a molecular mass of 16.6 kDa.