Search results for: Application
#34118779 2021/06/02 To Up
Neural optimal tracking control of constrained nonaffine systems with a wastewater treatment application.In this paper, we aim to solve the optimal tracking control problem for a class of nonaffine discrete-time systems with actuator saturation. First, a data-based neural identifier is constructed to learn the unknown system dynamics. Then, according to the expression of the trained neural identifier, we can obtain the steady control corresponding to the reference trajectory. Next, by involving the iterative dual heuristic dynamic programming algorithm, the new costate function and the tracking control law are developed. Two other neural networks are used to estimate the costate function and approximate the tracking control law. Considering approximation errors of neural networks, the stability analysis of the proposed algorithm for the specific systems is provided by introducing the Lyapunov approach. Finally, via conducting simulation and comparison, the superiority of the developed optimal tracking method is confirmed. Moreover, the trajectory tracking performance of the wastewater treatment application is also involved for further verifying the proposed approach.
Ding Wang, Mingming Zhao, Mingming Ha, Jin Ren
2634 related Products with: Neural optimal tracking control of constrained nonaffine systems with a wastewater treatment application.0.1ml (1mg/ml)0.2ml 100ul0.1ml 100ul 100ul 100ul 100ul100ug Lyophilized100ug Lyophilized50ul
#34118775 2021/04/06 To Up
Modelling the precipitation of nanoparticles in a closed medium in the presence of seeds: Application to amorphous silica synthesis.Seed-mediated methods are widely used in industrial or academic laboratories for the synthesis of nanoparticles of controlled shape and size. In the natural medium, precipitation of secondary minerals also often take place on seeds. In this context, we have devised a formalism which accounts for the competition between seed growth and nucleation and growth of secondary particles in an initially over-saturated aqueous solution. Based on the classical nucleation theory, it involves a size-dependent growth law which accounts for Ostwald ripening effects, unlike most water-rock interaction codes. We find that, in such closed system, seed growth and nucleation/growth of secondary particles are strongly coupled. In the multi-dimensional parameter space, regions where one or the other process prevails are well-separated by a rather abrupt transition. In general, the value of the initial seed total surface area is insufficient to fully orientate the synthesis. Relying on this approach, we propose an alternative interpretation of recent experimental results on amorphous silica nanoparticle synthesis. Besides fundamental understanding of the kinetics of precipitation, the interest of the present approach is to serve as a guideline to experimentalists or industrialists working in seed-mediated syntheses and warn on the undesired formation of secondary particles when monodispersed distributions of nano- or micro-particles are searched.
C Noguera, B Fritz, A ClÃ©ment, D Lemarchand
1572 related Products with: Modelling the precipitation of nanoparticles in a closed medium in the presence of seeds: Application to amorphous silica synthesis.1 100ul100ug Lyophilized100 100 μg
#34118751 2021/06/06 To Up
A computational pipeline for data augmentation towards the improvement of disease classification and risk stratification models: A case study in two clinical domains.Virtual population generation is an emerging field in data science with numerous applications in healthcare towards the augmentation of clinical research databases with significant lack of population size. However, the impact of data augmentation on the development of AI (artificial intelligence) models to address clinical unmet needs has not yet been investigated. In this work, we assess whether the aggregation of real with virtual patient data can improve the performance of the existing risk stratification and disease classification models in two rare clinical domains, namely the primary SjÃ¶gren's Syndrome (pSS) and the hypertrophic cardiomyopathy (HCM), for the first time in the literature. To do so, multivariate approaches, such as, the multivariate normal distribution (MVND), and straightforward ones, such as, the Bayesian networks, the artificial neural networks (ANNs), and the tree ensembles are compared against their performance towards the generation of high-quality virtual data. Both boosting and bagging algorithms, such as, the Gradient boosting trees (XGBoost), the AdaBoost and the Random Forests (RFs) were trained on the augmented data to evaluate the performance improvement for lymphoma classification and HCM risk stratification. Our results revealed the favorable performance of the tree ensemble generators, in both domains, yielding virtual data with goodness-of-fit 0.021 and KL-divergence 0.029 in pSS and 0.029, 0.027 in HCM, respectively. The application of the XGBoost on the augmented data revealed an increase by 10.9% in accuracy, 10.7% in sensitivity, 11.5% in specificity for lymphoma classification and 16.1% in accuracy, 16.9% in sensitivity, 13.7% in specificity in HCM risk stratification.
Vasileios C Pezoulas, Grigoris I Grigoriadis, George Gkois, Nikolaos S Tachos, Tim Smole, Zoran BosniÄ, Matej PiÄulin, Iacopo Olivotto, Fausto Barlocco, Marko Robnik-Å ikonja, Djordje G Jakovljevic, Andreas Goules, Athanasios G Tzioufas, Dimitrios I Fotiadis
2751 related Products with: A computational pipeline for data augmentation towards the improvement of disease classification and risk stratification models: A case study in two clinical domains.
#34118747 2021/06/09 To Up
Zinc oxide nanoparticles alleviates the adverse effects of cadmium stress on Oryza sativa via modulation of the photosynthesis and antioxidant defense system.C
Mohammad Faizan, Javaid Akhter Bhat, Kamel Hessini, Fangyuan Yu, Parvaiz Ahmad
2194 related Products with: Zinc oxide nanoparticles alleviates the adverse effects of cadmium stress on Oryza sativa via modulation of the photosynthesis and antioxidant defense system.500 Units1mg111 ml100.00 ul12000 IU500 Units
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#34118729 2021/06/09 To Up
Establishing paediatric diagnostic reference levels using reference curves - A feasibility study including conventional and CT examinations.To derive Regional Diagnostic Reference Levels (RDRL) for paediatric conventional and CT examinations using weight-based DRL curves and compare the outcome with DRL derived using the weight groups.
Anja AlmÃ©n, JÃ³nÃna GuÃ°jÃ³nsdÃ³ttir, Nils Heimland, Britta HÃ¸jgaard, Hanne Waltenburg, Anders Widmark
2431 related Products with: Establishing paediatric diagnostic reference levels using reference curves - A feasibility study including conventional and CT examinations.1 g1 g1 g
#34118723 2021/05/24 To Up
Design, synthesis, and biological evaluation of novel sulindac derivatives as partial agonists of PPARÎ³ with potential anti-diabetic efficacy.Peroxisome proliferator-activated receptor gamma (PPARÎ³) is a valuable drug target for diabetic treatment and ligands of PPARÎ³ have shown potent anti-diabetic efficacy. However, to overcome the severe side effects of current PPARÎ³-targeted drugs, novel PPARÎ³ ligands need to be developed. Sulindac, an identified ligand of PPARÎ³, is widely used in clinic as a non-steroidal anti-inflammatory drug. To explore its potential application for diabetes, we designed and synthesized a series of sulindac derivatives to investigate their structure-activity relationship as PPARÎ³ ligand and potential anti-diabetic effect. We found that meta-substitution in sulindac's benzylidene moiety was beneficial to PPARÎ³ binding and transactivation. Z rather than E configuration of the benzylidene double bond endowed derivatives with the selectivity of PPARÎ³ activation. The indene fluorine is essential for binding and regulating PPARÎ³. Compared with rosiglitazone, compound 6b with benzyloxyl meta-substitution and Z benzylidene double bond weakly induced adipogenesis and PPARÎ³-targeted gene expression. However, 6b potently improved glucose tolerance in a diabetic mice model. Unlike rosiglitazone, 6b was devoid of apparent toxicity to osteoblastic formation. Thus, we provided some useful guidelines for PPARÎ³-based optimization of sulindac and an anti-diabetic lead compound with less side effects.
Fengyu Huang, Zhiping Zeng, Weidong Zhang, Zhiqiang Yan, Jiayun Chen, Liangfa Yu, Qian Yang, Yihuan Li, Hongyu Yu, Junjie Chen, Caisheng Wu, Xiao-Kun Zhang, Ying Su, Hu Zhou
2679 related Products with: Design, synthesis, and biological evaluation of novel sulindac derivatives as partial agonists of PPARÎ³ with potential anti-diabetic efficacy.100μl100ug Lyophilized100ug Lyophilized100ul100ug Lyophilized100 ul100ug
#34118676 2021/06/05 To Up
Phthalic acid esters degradation by a novel marine bacterial strain Mycolicibacterium phocaicum RL-HY01: Characterization, metabolic pathway and bioaugmentation.P
Lei Ren, Guan Wang, Yongxiang Huang, Jianfu Guo, Chengyong Li, Yang Jia, Sha Chen, John L Zhou, Hanqiao Hu
2764 related Products with: Phthalic acid esters degradation by a novel marine bacterial strain Mycolicibacterium phocaicum RL-HY01: Characterization, metabolic pathway and bioaugmentation.10 mg10 mg50 mg1 mg10 g100ug Lyophilized 1 G 1 G 5 G 25 G 5 G100 μl
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#34118675 2021/05/26 To Up
Soil applied Ca, Mg and B altered phyllosphere and rhizosphere bacterial microbiome and reduced Huanglongbing incidence in Gannan Navel Orange.Huanglongbing (HLB) caused by 'Ca. Liberibacter. Asiaticus (Clas)' is one of the destructive diseases for citrus, threatening the development of citrus industry. Adopting a proper fertilization method instead of using pesticides seems particularly important, which would contribute to a sustainable development of orchard. In this study, the impact of soil application of nutrients combined with foliar spray of macro- and micro-nutrients on the incidence of HLB and the phyllosphere and rhizosphere bacterial microbiome was investigated in Gannan Navel Orange orchard from 2015 to 2018. Compared with the control (T1), the yield of Gannan Navel Orange in all other treatments applied with macro- and micro-nutrients increased significantly in 2018 (by 20.5%-45.8%), but not in the first two years (2016-17). Among treatments, Ca + Mg + B application in soil (T2) showed the highest yield and lowest HLB incidence. According to the PCR results, CLas was negative in T2 but positive in the control, which directly proved HLB incidence was reduced with Ca + Mg + B application in soil. Moreover, 16S rRNA sequencing was used to characterize rhizosphere and phyllosphere microbial communities. Results showed that microbial biodiversity was increased and microbial community structure was altered in T2 treatment, of which the beneficial bacteria were enriched in phyllosphere and rhizosphere. The results of PICRUSt showed that in T2 treatment, rhizosphere microbe contained more membrane transport (ABC transporters) genes, while, carbohydrate metabolism genes were enriched in the control rhizosphere due to HLB obstruct the photosynthetic metabolite transport. In summary, results indicated that macro- and micro-nutrients application improved the yield of Gannan Navel Orange and soil application of Ca + Mg + B reduced HLB incidence by altering microbial community structure and increasing microbial biodiversity. This study developed an environment-friendly way to reduce HLB incidence and improve the yield of citrus.
Yingjie Zhou, Yanni Tang, Chengxiao Hu, Ting Zhan, Simin Zhang, Miaomiao Cai, Xiaohu Zhao
2946 related Products with: Soil applied Ca, Mg and B altered phyllosphere and rhizosphere bacterial microbiome and reduced Huanglongbing incidence in Gannan Navel Orange.1000 TESTS/0.65ml25 mg96T 5 G100 mg25 mg250 Units100 mg 25 MG100ul10 mg
#34118663 2021/06/01 To Up
Improved agricultural Water management in data-scarce semi-arid watersheds: Value of integrating remotely sensed leaf area index in hydrological modeling.In watersheds located in semi-arid regions, vegetation dynamics, evapotranspiration (ET), and associated water and energy balances collectively play a major role in controlling hydrological regimes and crop yield. As such, it is challenging to predict the complex hydrological processes and biophysical dynamics. This challenge increases in areas with limited data availability. The key objective of this study was to evaluate the direct integration of remotely sensed Leaf Area Index (LAI) data into a hydrological model to improve streamflow, ET, and crop yield estimates. We also demonstrated how an improved model integrated with remotely sensed LAI data can inform water managers by predicting water productivity (WP) under different irrigation schemes. We took agricultural-dominated San Joaquin Watershed in California, United States, as our testbed and integrated the Moderate Resolution Imaging Spectroradiometer (MODIS) 500-m resolution 4-day total LAI data into the SWAT (Soil and Water Assessment Tool) model. Results showed that, compared to conventional SWAT model that relies on semi-empirical equations and user inputs for simulating biophysical processes, direct LAI integration into SWAT model (SWAT-LAI) notably captured the actual vegetation dynamics and improved ET and crop yield estimations. The WP simulated by the improved SWAT-LAI model for almond and grape yields varied within a range from 0.363 to 3.81 kg/m and 0.32 to 4.76 kg/m across different irrigation applications. The outcomes of this study showed that deficit irrigation application could be a viable option in water stressed regions, since it can save a substantial amount of irrigation water and maintain the higher water productivity required for both almond and grape yield production. This study shows an evidence of how remotely sensed data integrated into hydrological models can serve as a decision support tool by providing quantitative information on crop water use and crop production.
Manashi Paul, Adnan Rajib, Masoud Negahban-Azar, Adel Shirmohammadi, Puneet Srivastava
1597 related Products with: Improved agricultural Water management in data-scarce semi-arid watersheds: Value of integrating remotely sensed leaf area index in hydrological modeling.case1600100ugcase100ug1 L.50μl
#34118661 2021/06/04 To Up
Degradation of antibiotic Cephalosporin C in different water matrices by ionizing radiation: Degradation kinetics, pathways, and toxicity.Cephalosporin antibiotics are ubiquitous emerging pollutants in various aquatic environments due to their extensive production and application. Herein, the radiolytic degradation of antibiotic Cephalosporin C (CEP-C) in different water matrices was comprehensively investigated using gamma radiation at various experimental conditions. The results revealed that CEP-C oxidation obeyed pseudo first-order kinetics, and 100%, 94.9%, 67.0%, 44.6% and 34.5% removal of CEP-C with 10-200 mg/L was achieved at 0.4 kGy, respectively. The degradation was faster at higher absorbed dose and acidic conditions (pH = 3.5). The inorganic anions, including SO, NO, and HCO, had negative influence on the degradation of CEP-C, the corresponding rate constant decreased from 4.603 to 3.667, 1.677 and 2.509 kGy respectively in the presence of SO, NO, and HCO. The analysis of intermediate products indicated that CEP-C was oxidized to generate about 10 intermediate products. Besides, it was inferred that the thioether sulfur oxidation, Î²-lactam ring opening, acetyl dissociation from dihydrothiazine ring and D-Î±-aminohexylamide group abscission were the major reaction mechanisms of CEP-C degradation by gamma radiation. Importantly, the antibacterial activity of CEP-C could be completely vanished by gamma radiation alone, while more toxic intermediate products might be formed. Addition of hydrogen peroxide and peroxymonosulfate could significantly improve the CEP-C degradation, and reduce the toxicity of intermediates of CEP-C degradation. Similar degradation behavior was observed in the groundwater and wastewater, implying that ionizing radiation can be used for degradation of Cephalosporin in water and wastewater.
Xiaoying Chen, Jianlong Wang
2862 related Products with: Degradation of antibiotic Cephalosporin C in different water matrices by ionizing radiation: Degradation kinetics, pathways, and toxicity.1 mg50μl100 μg10 ug100ug20 ul (10 mM)
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