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Search results for: Biotin

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#32783282   2020/08/11 To Up

MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury.

M
Jian Tan, Zhiguo Wu, Jun Liu, Wenting Zhang, Wanqiu Yuan, Hong Peng

2260 related Products with: MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury.

50 ul96 assays 96T48 assays 48 samples0.1ml (1mg/ml)100 ul96 assays 48 assays

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#32780133   // To Up

Trends in Daily Use of Biotin Supplements Among US Adults, 1999-2016.


Danni Li, Mary R Rooney, Lynn A Burmeister, Nicole E Basta, Pamela L Lutsey

1581 related Products with: Trends in Daily Use of Biotin Supplements Among US Adults, 1999-2016.

100 μg100ug Lyophilized100 μg100ug100ug100 μg100ug100ug100ug1 mg100ug Lyophilized100ug

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#32767028   2020/08/06 To Up

Circ_0068655 Promotes Cardiomyocyte Apoptosis via miR-498/PAWR Axis.

The cardiomyocyte apoptosis is considered as one of major contributions to cardiac remodeling after myocardial infarction (MI). Numerous studies find that circular RNAs (circRNAs) play pivotal roles in a variety of biological functions. However, the role of circ_0068655 in MI and human induced pluripotent stem-derived cardiomyocytes (HCMs) remains unknown.
Qiaoying Chai, Mingqi Zheng, Le Wang, Mei Wei, Yajuan Yin, Fangfang Ma, Xinping Li, Haijun Zhang, Gang Liu

2759 related Products with: Circ_0068655 Promotes Cardiomyocyte Apoptosis via miR-498/PAWR Axis.

100 ug/vial25 assays1 kit50μg/vial100ug/vial1000 assays100ug Lyophilized100 per bag, 10 bags per 100ul100 ug/vial100 ug500

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#32764161   2020/08/07 To Up

Biotin interference in cardiac troponin immunoassay - where the wild things are?


Paul Collinson

2938 related Products with: Biotin interference in cardiac troponin immunoassay - where the wild things are?

100ug Lyophilized1mg11 mg100ug100ug Lyophilized50 500 200 96 tests

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#32763304   2020/08/04 To Up

A colorimetric aptamer-based method for detection of cadmium using the enhanced peroxidase-like activity of Au-MoS nanocomposites.

In this work, a colorimetric aptamer-based method for detection of cadmium using gold nanoparticles modified MoS nanocomposites as enzyme mimic is established. In short, biotinylated Cd aptamers are immobilized by biotin-avidin binding on the bottoms of the microplate, the complementary strands of Cd aptamers are connected to the Au-MoS nanocomposites which have the function of enhanced peroxidase-like activity. The csDNA-Au-MoS signal probe and target Cd compete for binding Cd aptamer, the color change can be observed by addition of chromogenic substrate, thereby realizing visual detection of Cd. The absorbance of the solution at 450 nm has a clear linear relationship with the Cd concentration. The linear range is 1-500 ng/mL, and the limit of detection is 0.7 ng/mL. The assay was used to test white wine samples, the results are consistent with those of atomic absorption spectrometry; which prove that this method can be used for detection of Cd in real samples.
Zui Tao, Liting Wei, Shijia Wu, Nuo Duan, Xiang Li, Zhouping Wang

2224 related Products with: A colorimetric aptamer-based method for detection of cadmium using the enhanced peroxidase-like activity of Au-MoS nanocomposites.

100tests100tests100tests100tests100tests100tests100tests100tests100tests100tests100Tests

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#32762597   2020/08/05 To Up

Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements.

In this study, we aimed to determine the incidence of hair loss in patients who underwent laparoscopic sleeve gastrectomy (LSG), and to observe whether use of Biotin has an impact on hair loss. This study included 156 female patients who underwent LSG for obesity and completed a 1-year follow-up. All patients with vitamin deficiency were screened in the pre- and postoperative period. Hair loss was defined as the subjective perception of the women of losing a higher amount of hair when compared with normal situation. Hair loss was observed in 72% of the patients after LSG ( = 112). Seventy-nine percent of the patients reported hair loss between the third and fourth-month interval, and continued for an average of 5.5 ± 2.6 months. Permanent alopecia was not observed in any of the patients. Patients who experienced hair loss and Biotin deficiency after LSG were prescribed 1000 mcg/day of Biotin for 3 months. Of these 22 patients; only 5 (23%) patients reported a remarkable decline in hair loss. İn addition, 29 patients were found to take 1000 mcg/day of Biotin for average 2.5 months after onset of hair loss by their own initiative, despite optimal blood Biotin levels. Eleven (38%) patients reported a remarkable decline in hair loss. The effect of biotin use on hair loss in patients with and without biotin deficiency was compared. There was no significant difference ( = .2). Temporary hair loss after LSG is common. It was found that biotin supplementation used to prevent hair loss does provide low efficacy.
Ozan Şen, Ahmet Gökhan Türkçapar

1428 related Products with: Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements.

100 5 mg100ug100ug Lyophilized100ug100ug Lyophilized100ug Lyophilized0.5 mg25 50 μg500 50

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#32761325   2020/08/05 To Up

The Rise and Fall of High-Dose Biotin to Treat Progressive Multiple Sclerosis.


Carolyn H Goldschmidt, Jeffrey A Cohen

1755 related Products with: The Rise and Fall of High-Dose Biotin to Treat Progressive Multiple Sclerosis.

1ml

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#32761258   2020/08/05 To Up

Detection of biotin with zeptomole sensitivity using recombinant spores and a competition assay.

Detection of protein-binding analytes is important for many applications. Currently, various instrument-based techniques are used for detecting protein-binding analytes. However, such techniques have several limitations including high cost and time-consuming sample processing. In order to overcome these limitations, we developed a sensitive competition assay for the detection of protein-binding analytes using recombinant endospores as a sensing element. The method is based on the competition between the biotin, the model analyte, and a biotin-magnetic bead complex to bind the recombinant spores containing the biotin binding region of streptavidin. After magnetic attraction, the residual spores in the suspension are spread on plates to form colonies which are used to count the amount of the residual spores; the higher the residual ratio of spores, the more biotin in the samples. The linear range was from 150 zmol to 1.5 fmol and the limit of detection of the assay was 150 zmol. The assay proposed herein is sensitive and does not require any expensive equipment. It is suitable for qualitative or semi-quantitative analysis such as screening tests for the detection of toxic chemicals.
Wen-Zhi Lin, Wan-Chun Liao, Fang-Hsi Chen, I-Cheng Ma, Shao-Yi Hou

1230 related Products with: Detection of biotin with zeptomole sensitivity using recombinant spores and a competition assay.

100tests100ul250tests100tests100tests100tests100tests100μl100tests100tests100μl

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#32759698   2020/08/04 To Up

Transungual Delivery, Anti-Inflammatory Activity, and In Vivo Assessment of a Cyclodextrin Polypseudorotaxanes Nail Lacquer.

A new cyclodextrin polypseudorotaxanes nail lacquer (Regenail) containing biotin, methyl sulphonyl methane (MSM), and dimethylsilanediol salicylate was developed and evaluated in vitro and in vivo. The product was developed to improve nail status and diminish signs of pathological nail alterations. A reference product (Betalfatrus) was used for comparative purposes. An in vitro permeation experiment in hooves showed high MSM and biotin absorption. The content of sulfur and silicon in hooves was also found to be higher compared with the reference product. MSM was tested in human keratinocytes, exhibiting a good cytotoxicity profile and anti-inflammatory activity by the reduction in IL-8 and TNF-α under LPS stimuli. A clinical study was performed to check product safety and efficacy against nail brittleness and alterations such as Beau's lines and onychorrhexis. A reduction in both alterations and in surface roughness without alteration of nail structure was observed, with a good level of patient acceptance and satisfaction.
Francisco Fernández-Campos, Francesc Navarro, Adrian Corrales, Jordi Picas, Eloy Pena, Jordi González, Francisco J Otero-Espinar

2184 related Products with: Transungual Delivery, Anti-Inflammatory Activity, and In Vivo Assessment of a Cyclodextrin Polypseudorotaxanes Nail Lacquer.

0.1ml (1mg/ml)100 μg100 μg100ug Lyophilized100 μg100ug100 μg100 100 μg100 μg

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