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#32619871   2020/06/24 To Up

Ultrasound vibro-elastography for assessing mechanical properties of porcine reproductive tissues in an ex vivo model.

The aim of this study was to use ultrasound vibro-elastography (UVE) for measuring surface wave speed and assessing mechanical properties of ex vivo porcine reproductive tissues, including the uterus, bladder, cornua and cervix.
Boran Zhou, Juntao Shao, Cassandra K Kisby, Xiaoming Zhang

1501 related Products with: Ultrasound vibro-elastography for assessing mechanical properties of porcine reproductive tissues in an ex vivo model.

100 μg900 tests48 samples50

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#32619674   2020/06/30 To Up

Tropisetron ameliorates cyclophosphamide-induced hemorrhagic cystitis in rats.

Hemorrhagic cystitis is one of the most important complications of cyclophosphamide, a drug widely used in cancer chemotherapy and bone marrow transplantation. 5-HT antagonists are anti-emetic agents and have been shown to have notable anti-inflammatory and antioxidant properties. This study was designed to investigate the possible protective effects of tropisetron against cyclophosphamide-induced hemorrhagic cystitis in rats. Hemorrhagic cystitis was induced in female rats by cyclophosphamide (270 mg/kg). Tropisetron (2.5, 5 and 7.5 mg/kg), granisetron (2.5 and 5 mg/kg), and ondansetron (5 mg/kg) were injected 15 min before, 4 and 8 h after cyclophosphamide. To evaluate the role of alpha7 nicotinic acetylcholine receptor (α7nAChR), its antagonist, methyllycaconitine (5 mg/kg) was administered 30 min before tropisetron. After 24 h, animals were killed under anesthesia. Macroscopic and histological changes were evaluated. Malondialdehyde (MDA), glutathione (GSH) and Evans blue were measured spectrophotometrically. Furthermore, the protein levels of p38 mitogen-activated protein kinases (P38 MAPK), p-P38, signal transducer and activator of transcription 3 (STAT3), p-STAT3 and Poly (ADP-ribose) polymerase (PARP) were determined using Western blot. Cyclophosphamide administration significantly induced histopathological damages and increased MDA, p-p38/p38, p-STAT3/STAT3, and PARP levels compared with the saline group. Tropisetron treatment diminished histopathological injuries as well as MDA level, and STAT3 activity compared to cyclophosphamide treated rats. Co-administration of methyllycaconitine with tropisetron, partially or completely reversed the protective effects of tropisetron. Our results showed that prophylactic administration of tropisetron markedly ameliorated the cyclophosphamide-induced bladder hemorrhage and inflammation in rats. These effects of tropisetron were α7nAChR dependent.
Mohammad Reza Zirak, Gholamreza Karimi, Reza Rahimian, Amir Hossein Jafarian, A Wallace Hayes, Soghra Mehri

1121 related Products with: Tropisetron ameliorates cyclophosphamide-induced hemorrhagic cystitis in rats.

50 ul96 assays1 mg 100ul5ug2ug100ug100 ul400 ug100ug100 ul400 ug

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#32619653   2020/06/30 To Up

Analysis on the diagnosis of infection risk factors and the incidence of ureteroscopy holmium laser lithotripsy and vagal excitation under computed tomography image information health technology.

It was to explore the corresponding preventive measures based on the analysis of the main risk factors of systemic inflammatory response syndrome (SIRS) after the ureteroscopy holmium laser lithotripsy, so as to reduce the incidence rate of postoperative SIRS and vagal nerve excitement in patients with renal stones. 148 patients treated with the ureteroscopy holmium laser lithotripsy in our hospital from January 2018 to December 2019 were selected as the research objects. The total abdominal computed tomography (CT) plain scan and three-dimensional imaging were used for examination before surgery, and the Kidney, ureter, bladder (KUB) was used to evaluate the treatment effects after surgery. The objects were divided into the large stone group (>20mm) and the small stone group (≤20mm). The differences in stone sites and stone length and diameter between the age and sex of patients in the two groups were recorded and compared, and the stone clearance rate and complications in the two groups were evaluated. Through the Pearson chi-square test and multivariate Logistic regression analysis of the risk factors related to postoperative SIRS, the occurrence of vagal excitation in patients after ureteral soft mirror holmium laser lithotripsy was analysed, it found that there was no statistical difference in stone sites of age and sex between the two groups (P>0.05), and there was no statistical difference in stone clearance rate and postoperative complications between the two groups (P>0.05), while the difference in operation time between the two groups was statistically significant (P<0.05). According to the regression analysis, there was a significant positive correlation between the time of operation, positive urine culture in the middle before operation, infectious calculus, and postoperative SIRS (P<0.05). 78 patients suffered from vagal excitation during the surgery, and the incidence rate was 52.7%. The results showed that the treatment of kidney stones with a diameter more than 20mm and no more than 20mm by holmium laser lithotripsy under ureter-scope had good clinical effect. The operative time, positive urine culture in the middle part of the operation, and infectious stones were included in the main risk factors for the occurrence of SIRS after ureter-scope holmium laser lithotripsy and has a certain impact on the renal nerve trunk while crushing stones.
Yuelong Zhang, Qi Zhang, Jia Lv, Dahong Zhang

2453 related Products with: Analysis on the diagnosis of infection risk factors and the incidence of ureteroscopy holmium laser lithotripsy and vagal excitation under computed tomography image information health technology.

110 mg2100.00 ul100 mg100ug 15 ml 200ul25 mg

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#32619603   2020/06/30 To Up

Near-infrared fluorescence imaging of ureters with intravenous indocyanine green during radical cystectomy to prevent ureteroenteric anastomotic strictures.

To determine whether intraoperative near-infrared fluorescence imaging (NFI) of the distal ureter using intravenous indocyanine green (ICG) could provide assessment of vascular adequacy and potentially decrease the risk of ureteroenteric anastomotic stricture (UAS).
Chirag P Doshi, Amy Wozniak, Marcus L Quek

2329 related Products with: Near-infrared fluorescence imaging of ureters with intravenous indocyanine green during radical cystectomy to prevent ureteroenteric anastomotic strictures.

1 kit1 kit1 kit1 kit0.5 umol1 kit25 Tests1 kit1 kit1 kit1 kit1 kit

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#32619597   2020/06/30 To Up

Relevance of the endoscopic evaluation in the diagnosis of Bladder Pain Syndrome/Interstitial Cystitis.

In 2008 the European Society for the Study of Interstitial Cystitis (ESSIC) established the diagnostic criteria and classification of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC), based on clinical features and cystoscopy results. The present study aims to assess the relevance of the endoscopic evaluation in clinically suspected cases of BPS/IC, using ESSIC criteria.
Alessandro Morlacco, Mariangela Mancini, Matteo Soligo, Fabio Zattoni, Arturo Calpista, Giuseppe Vizzielli, Rosario Patti, Francesco Gerardo Mandato, Andrea Celeste Barneschi, Filiberto Zattoni, Massimo Iafrate, Fabrizio Dal Moro,

2456 related Products with: Relevance of the endoscopic evaluation in the diagnosis of Bladder Pain Syndrome/Interstitial Cystitis.

12000 IU

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#32619594   2020/06/30 To Up

Sacral Neuromodulation: Determining Predictors of Success.

To determine predictors of success for sacral neuromodulation in women with overactive bladder, urinary retention, and fecal incontinence.
Tara Nikonow Morgan, Natalie Pace, Anand Mohapatra, Dianxu Ren, Gregory Kunkel, Lauren Tennyson, Jonathan P Shepherd, Christopher J Chermansky

1625 related Products with: Sacral Neuromodulation: Determining Predictors of Success.

5 G

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#32619233   2020/07/03 To Up

Risk of bowel fistula following surgical management of deep endometriosis of the rectosigmoid: a series of 1102 cases.

What are the risk factors and prevalence of bowel fistula following surgical management of deep endometriosis infiltrating the rectosigmoid and how can it be managed?
Horace Roman, Valérie Bridoux, Benjamin Merlot, Benoit Resch, Rachid Chati, Julien Coget, Damien Forestier, Jean-Jacques Tuech

1667 related Products with: Risk of bowel fistula following surgical management of deep endometriosis of the rectosigmoid: a series of 1102 cases.

5 G

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#32619021   2020/07/03 To Up

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.

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Brittany M Bowman, Stephanie A Montgomery, Travis P Schrank, Jeremy M Simon, Travis S Ptacek, Tigist Y Tamir, Kathleen M Muvlaney, Seth J Weir, Tuong T Nguyen, Ryan M Murphy, Liza Makowski, D Neil Hayes, Xiaoxin L Chen, Scott H Randell, Bernard E Weissman, Michael B Major

1490 related Products with: A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.

100.00 ug

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#32619015   2020/06/23 To Up

Neonatal Bladder-derived Mesenchymal Stem Cells Ameliorate Bladder Dysfunction in Diabetic Rat Models.

To evaluate the effect of a new mesenchymal stem cell type derived from the neonatal bladder (nMSC-B) on diabetic bladder dysfunction (DBD).
Mehmet Salih Boga, Ahmet Hakan Haliloğlu, Ömer Gülpınar, Asım Özayar, Mehmet Giray Sönmez, Ferda Alpaslan Pinarli, Emre Boğa, Tangül Pinarci, Meral Tiryaki, Orhan Göğüş

1571 related Products with: Neonatal Bladder-derived Mesenchymal Stem Cells Ameliorate Bladder Dysfunction in Diabetic Rat Models.

10 ug5 x 10A5 cells/vial1.00 flask

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#32618823   2020/06/17 To Up

Porcine Urinary Bladder Extracellular Matrix for Treatment of Periocular Skin Defects.

To describe the experience of 4 oculoplastic surgeons with porcine bladder matrix for periocular anterior lamella and donor site skin defects either as stand-alone treatment or in conjunction with other reconstructive procedures. The authors hypothesized that defect size and location influence the requirement for additional matrix treatments or ancillary procedures.
James J Law, Laura X Baker, Qingxia Chen, Louise A Mawn, Behin Barahimi, Anna C Kupcha, Mark A Alford, Rachel K Sobel

1090 related Products with: Porcine Urinary Bladder Extracellular Matrix for Treatment of Periocular Skin Defects.

0.1 mg25mg100 ug250 1 ml10 ml

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