Product name :Active Akt3

Catalog Number :7703-5

Quantity :5 μg

Price :249.00 €

Pay now with :

Supplier :Biovision

Alternate Names / Synonyms: Active Akt3, Akt3, human Akt3, active kinase, active kinases, Akt, recombinant Akt3, recombinant Akt, kinase activity assay, protein kinase, akt-3, akt 3

Gene Symbol: AKT3

Accession #: NP_005456

Gene ID: 10000

Source: Baculovirus (Sf9 insect cells)

Appearance: Liquid

Physical Form Description: Recombinant proteins in storage buffer (50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol).

Molecular Weight: ~84.0 kDa

Purity by SDS-PAGE: ≥90%

Purity by HPLC: N/A

Endotoxin Level: N/A

Biological Activity: 206 nmol phosphate incorporated into Akt substrate peptide per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 µM ATP and total of 0.83 µCi/µl P-32.

Reconstitution Instructions: N/A

Storage Temp.: -80°C

Shipping: gel pack

Background Information: Akt3 or Protein Kinase B γ (PKB) is a serine/threonine kinase that is a member of the Akt family. In mammals, the Akt family comprises of three highly homologous members known as Akt1 (PKB), Akt2 (PKB), and Akt 3. Akt 3 like the other family members is activated in cells exposed to diverse stimuli such as hormones, growth factors, and extracellular matrix components. The activation mechanism remains to be fully characterized but occurs downstream of phosphoinositide 3-kinase (PI3K). PI3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP3), a lipid second messenger essential for the translocation of Akt family members to the plasma membrane where they are phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1) and phosphoinositide-dependent kinase-2 (PDK-2 possibly ILK). Akt 3 like the other family members phosphorylates and regulates the function of many cellular proteins involved in processes that include cellular metabolism, survival/apoptosis, and proliferation. Recent evidence indicates that Akt 3 is frequently overexpressed in many types of human cancers including breast and prostate. Although the mechanisms have not yet been fully characterized, increased expression and activation of Akt is believed to promote cell proliferation and survival thereby contributing to cancer progression.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans.

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1087-25 Active Human Caspase 725 units Biovision 25 units 183.33€
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IPOPAI-1mg Porcine PAI-1 (wild type active form) 1mg Innovative Research INC 1 571.00€ Pub
7763-100 Active p38 beta Biovision 100 μg 2 074.00€ Pub
7725-5 Active p70 S6K Biovision 5 ug 303.00€
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Y051512 Anti- ADAM-19 (A Disintigrin And Metalloproteinase-19, Meltrin-beta); Amino end active ADAM-19 Antibody ABM Goods 100μg 811.65€
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1181-100 Active Mouse Caspase 1100 units Biovision 100 units 295.79€
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IRPAI-I91L-1mg Rat PAI-1 (stable active mutant) 1mg Innovative Research INC 1 571.00€ Pub
03-003 Fibroblast Growth Factor 1 (FGF 1), human, active Full length recombinant mature FGF 1 (15.8 kDa, 140 amino acids) expressed in E. coli.FGF 1 (acidic FGF) is a member of the fibroblast growth factor ( B-Bridge 50 ug 253.05€
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901-V Allergens, Dermatophagoides pteronyssinus Der P1 antigen . Full length. Non enzymatically active. Virogen 100ug/vial 216.00€
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7735-5 Active CHK1 Biovision 5 μg 249.00€
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7738-5 Active CK2a1 Biovision 5 ug 303.00€
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3259-100 Caspase-8 (Active) Antibody Biovision 100 322.00€
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K198-25 CaspGLOW Red Active Caspase 8 Staining Kit Biovision 25 assays 200.00€
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1083-10 Active Human Caspase 310 ug Biovision 10 ug 419.58€
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IMTPA-0.1mg Active Mouse tPA recombinant 0.1mg Innovative Research INC 0.1mg 725.00€
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7754-5 Active P38delta Biovision 5 ug 303.00€
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7715-5 Active Lyn B Biovision 5 μg 249.00€
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RF003-5 r Human TGF â 2 Active Argenvec 5ìg 278.83€ Pub
1090A-25 Active Human Caspase 10 a25 units Biovision 25 units 183.33€
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IRbPAI-0.5mg Rabbit PAI-1 (wild type active form 0.5mg Innovative Research INC 980.00€
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7765-5 Active FRK Biovision 5 ug 303.00€
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7727-5 Active PAK75 ug Biovision 5 ug 231.00€
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Y213392 AKT3 ABM Goods 200ul 520.80€
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1188-25 Active Mouse Caspase 825 units Biovision 25 units 164.43€
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K180-25 CaspGLOW Fluorescein Active Caspase Staining Kit Biovision 25 assays 200.00€
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03-005-5 Keratinocyte Growth Factor (KGF FGF7), human, active B-Bridge 5 x 50 ug 871.50€
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90900-3 TGFâ1 Active Human Recombinant Protein BPS Bioscience 1 mg 8 860.00€
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