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#34130351   2021/06/15 To Up

Effects of Ultrashort Wave Therapy on Inflammation and Macrophage Polarization after Acute Lung Injury in Rats.

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Lan Li, Mengjian Qu, Lu Yang, Jing Liu, Qian Wang, Peirui Zhong, Yahua Zeng, Ting Wang, Hao Xiao, Danni Liu, Xiarong Huang, Jinling Wang, Jun Zhou

2934 related Products with: Effects of Ultrashort Wave Therapy on Inflammation and Macrophage Polarization after Acute Lung Injury in Rats.

1 mg8 Sample Kit16-22 Sample Kit2ug

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#34130334   2021/06/15 To Up

Drug-Induced Vanishing Bile Duct Syndrome: From Pathogenesis to Diagnosis and Therapeutics.

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Fernando Bessone, Nidia Hernández, Mario Tanno, Marcelo G Roma

2299 related Products with: Drug-Induced Vanishing Bile Duct Syndrome: From Pathogenesis to Diagnosis and Therapeutics.

1 mg430 tests600 Tests / Kit1 mL430 Tests / Kit0.1 mg 2 ml Ready-to-use 100 MG1 module250ug50 ul

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#34130299   2021/06/15 To Up

Human Neutrophil Elastase Mediates MUC5AC Hypersecretion via the Tumour Necrosis Factor-α Converting Enzyme-Epidermal Growth Factor Receptor Signalling Pathway in vivo.

The objective of this study is to examine the role of the tumour necrosis factor-α converting enzyme-epidermal growth factor receptor (TACE-EGFR) pathway in human neutrophil elastase (HNE)-induced MUC5AC mucin expression in mice.
Junmei Zhao, Tian Yang, Wei Qiao, Yu Ye, Jian Zhang, Qing Luo

1264 related Products with: Human Neutrophil Elastase Mediates MUC5AC Hypersecretion via the Tumour Necrosis Factor-α Converting Enzyme-Epidermal Growth Factor Receptor Signalling Pathway in vivo.

2 Pieces/Box100 μg4 Membranes/Box100 μg1 kit(96 Wells)5ug5 x 50 ug20ug5 x 50 ug1 kit(96 Wells)1 mg50 ug

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#34130288   2021/06/15 To Up

Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.

As disorder of tryptophan metabolism is common in CKD, the rate-limiting enzyme of tryptophan, indoleamine-2,3-dioxygenase (IDO), has been reported to be involved in CKD, while the accurate mechanism remains unknown. This study was designed to explore correlations between IDO and kidney fibrosis after ischemia-reperfusion injury (IRI).
Binbin Pan, Hao Zhang, Yali Hong, Mengqing Ma, Xin Wan, Changchun Cao

1721 related Products with: Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.

96T 100ul

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#34130232   2021/06/10 To Up

Promoting corn stover degradation via sequential processing of steam explosion and cellulase/lactic acid bacteria-assisted ensilage.

To improve the utilization efficiency of corn stover , steam explosion pretreatment and cellulase/lactic acid bacteria-assisted ensilage storage were conducted in sequence, mainly focusing on morphological structure, lignocellulose fraction, cellulose accessibility and degradation profile. The results showed that there was a synergistic effect of steam explosion and ensilage storage, where hemicellulose of corn stover was partly degraded during steam explosion processing (70%) or ensilage storage (20-40%). Meanwhile, its morphological structure was apparently broken, increasing cellulose accessibility (2.44, 2.83, 4.08-4.33 mg/g), where enzyme YDL and inoculant QZB were the two most effective additives. Furthermore, rumen effective degradability of corn stover (39.25%, 48.33%, 52.57-54.07%) were increased along with greater rapid degradation fraction (0, 1.67%, 9.16-11.62%) and degradation rate of slow degradation fraction (0.020, 0.034, 0.039-0.048 h) . In conclusions, it is suggested that treating corn stover with steam explosion processing and ensilage storage is a feasible way to improve its utilization efficiency.
Dechao Nie, Lingyun Yao, Xiaokai Xu, Zhuo Zhang, Yanling Li

1926 related Products with: Promoting corn stover degradation via sequential processing of steam explosion and cellulase/lactic acid bacteria-assisted ensilage.

100 G 100 Slides 100tests10 mg 1 kit(s) 100Tests100 MG1 kg 1 G100 ug/vial25 mg1 mg

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#34130222   2021/05/28 To Up

Lipolytic enzymes and free fatty acids at the endothelial interface.

Lipids released from circulating lipoproteins by intravascular action of lipoprotein lipase (LpL) reach parenchymal cells in tissues with a non-fenestrated endothelium by transfer through or around endothelial cells. The actions of LpL are controlled at multiple sites, its synthesis and release by myocytes and adipocytes, its transit and association with the endothelial cell luminal surface, and finally its activation and inhibition by a number of proteins and by its product non-esterified fatty acids. Multiple pathways mediate endothelial transit of lipids into muscle and adipose tissues. These include movement of fatty acids via the endothelial cell fatty acid transporter CD36 and movement of whole or partially LpL-hydrolyzed lipoproteins via other apical endothelial cell receptors such as SR-B1and Alk1. Lipids also likely change the barrier function of the endothelium and operation of the paracellular pathway around endothelial cells. This review summarizes in vitro and in vivo support for the key role of endothelial cells in delivery of lipids and highlights incompletely understood processes that are the focus of active investigation.
Ira J Goldberg, Ainara G Cabodevilla, Dmitri Samovski, Vincenza Cifarelli, Debapriya Basu, Nada A Abumrad

1420 related Products with: Lipolytic enzymes and free fatty acids at the endothelial interface.

1,000 tests500gm1kg100100gm500g50gm100g

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#34130217   2021/06/07 To Up

"Clicking" fragment leads to novel dual-binding cholinesterase inhibitors.

Cholinesterase inhibitors are potent therapeutics in the treatment of Alzheimer's disease. Among them, dual binding ligands have recently gained a lot of attention. We discovered novel dual-binding cholinesterase inhibitors, using "clickable" fragments, which bind to either catalytic active site (CAS) or peripheral anionic site (PAS) of the enzyme. Copper(I)-catalyzed azide-alkyne cycloaddition allowed to effectively synthesize a series of final heterodimers, and modeling and kinetic studies confirmed their ability to bind to both CAS and PAS. A potent acetylcholinesterase inhibitor with IC = 18 nM (compound 23g) was discovered. A target-guided approach to link fragments by the enzyme itself was tested using butyrylcholinesterase.
Zuzanna Molęda, Anna Zawadzka, Zbigniew Czarnocki, Leticia Monjas, Anna K H Hirsch, Armand Budzianowski, Jan K Maurin

1579 related Products with: "Clicking" fragment leads to novel dual-binding cholinesterase inhibitors.

1 ml100 µg5 g1 kit(96 Wells)1000 100 ml0.1 mg 2 ml Ready-to-use 0.2 mg1x96 well plate1 module50ug

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#34130214   2021/06/08 To Up

Lectins: Biological significance to biotechnological application.

Lectins are a set of non-enzymatic carbohydrate binding proteins appearing in all domains of life. They function to recognize, interact and bring about reversible binding of a specific sugar moiety present in a molecule. Since glycans are ubiquitous in nature and are an essential part of various biological process, the lectins are been investigated to understand the profile of these versatile but complex glycan molecule. The knowledge gained can be used to explore and streamline the various mechanisms involving glycans and their conjugates. Thus, lectins have gained importance in carbohydrate-protein interactions contributing to the development in the field of glycobiology. This has led to a deeper understanding of the importance of saccharide recognition in life. Since their discovery, the lectins have become a great choice of research in the field of glycobiology and their biological significances have recently received considerable attention in the biocontrol field as well as medical sectors.
Dixita Chettri, Manswama Boro, Lija Sarkar, Anil Kumar Verma

1800 related Products with: Lectins: Biological significance to biotechnological application.

0.1ml (1.3mg/ml) 100ul 100ul50ul25 mg0.5mg50ul 100ul 100ul 100ul 100ul 100ul

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#34130189   2021/06/10 To Up

Study on the influence of advanced treatment processes on the surface properties of polylactic acid for a bio-based circular economy for plastics.

New biotechnological processes using microorganisms and/or enzymes to convert carbonaceous resources, either biomass or depolymerized plastics into a broad range of different bioproducts are recognized for their high potential for reduced energy consumption and reduced GHG emissions. However, the hydrophobicity, high molecular weight, chemical and structural composition of most of them hinders their biodegradation. A solution to reduce the impact of non-biodegradable polymers spread in the environment would be to make them biodegradable. Different approaches are evaluated for enhancing their biodegradation. The aim of this work is to develop and optimize the ultrasonication (US) and UV photodegradation and their combination as well as dielectric barrier discharge (DBD) plasma as pre-treatment technologies, which change surface properties and enhance the biodegradation of plastic by surface oxidation and thus helping bacteria to dock on them. Polylactic acid (PLA) has been chosen as a model polymer to investigate its surface degradation by US, UV, and DBD plasma using surface characterization methods like X-ray Photoelectron Spectroscopy (XPS) and Confocal Laser Microscopy (CLSM), Atomic Force Microscopy (AFM) as well as FT-IR and drop contour analysis. Both US and UV affect the surface properties substantially by eliminating the oxygen content of the polymer but in a different way, while plasma oxidizes the surface.
Georgia Sourkouni, Charalampia Kalogirou, Philipp Moritz, Anna Gödde, Pavlos K Pandis, Oliver Höfft, Stamatina Vouyiouka, Antonis A Zorpas, Christos Argirusis

1089 related Products with: Study on the influence of advanced treatment processes on the surface properties of polylactic acid for a bio-based circular economy for plastics.

5 g 1 G10 mg 100 G25 g 1 G 1 G10 mg 1 G 1 G 500 G

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