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#32783367   2020/08/11 To Up

Pregnancy outcome and cost-effectiveness comparisons of artificial cycle-prepared frozen embryo transfer with or without GnRH agonist pretreatment for polycystic ovary syndrome: a randomized controlled trial.

To compare the live birth rate and cost effectiveness of artificial cycle-prepared frozen embryo transfer (AC-FET) with or without GnRH agonist (GnRH-a) pretreatment for women with polycystic ovary syndrome (PCOS).
Lu Luo, Minghui Chen, Yangxing Wen, Limei Zhang, Canquan Zhou, Qiong Wang

2212 related Products with: Pregnancy outcome and cost-effectiveness comparisons of artificial cycle-prepared frozen embryo transfer with or without GnRH agonist pretreatment for polycystic ovary syndrome: a randomized controlled trial.

100ul

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#32783043   2020/06/01 To Up

Challenges in the Management of Ectopic Parathyroid Pathologies: A Case Series of Five Patients.

In primary hyperparathyroidism (PHPT) the diagnosis and treatment of ectopic parathyroid adenomas (EPTA) is a challenging process for head and neck surgeons. We present five patients with EPTA in different locations, along with an in-depth discussion of imaging modalities. We used sestamibi scintigraphy (MIBI) and ultrasound as first line imaging tools in asymptomatic hypercalcemia and PHPT. Single photon emission computed tomography (SPECT) was combined with MIBI or computed tomography (CT) if a parathyroid pathology was not localized initially. Four-dimensional parathyroid CT (4D-CT) was the last imaging modality preferred to localize the ectopic parathyroid gland. We performed focused unilateral neck exploration (FUNE) with intraoperative frozen section analysis as a routine procedure for imaging-detected lesions. Bilateral neck exploration was performed for re-exploration cases and imaging-negative cases. Histopathology confirmed EPTA and postoperative serum calcium normalized in all cases. 4D-CT is promising for ectopic parathyroid gland localization if all other imaging modalities fail. Despite the advancements in imaging, surgical experience continues to play the central role in the management of ectopic parathyroid pathologies.
Adem Binnetoğlu, Berat Demir, Javahir Mamadlı

2740 related Products with: Challenges in the Management of Ectopic Parathyroid Pathologies: A Case Series of Five Patients.



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#32782902   2020/07/24 To Up

Effect of Preoperative Frozen Shoulder on Clinical Outcomes After Arthroscopic Rotator Cuff Repair.

A concomitant rotator cuff tear (RCT) with frozen shoulder is a common but challenging clinical scenario. The effect of frozen shoulder on clinical outcomes is open to discussion.
Jeung Yeol Jeong, Seung Bo Shim, Jin Ho Hong, Wooyoung Im, Sang Min Lee, Jae Chul Yoo

1862 related Products with: Effect of Preoperative Frozen Shoulder on Clinical Outcomes After Arthroscopic Rotator Cuff Repair.



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#32782846   2020/04/04 To Up

Robotic assisted partial nephrectomy with cold ischemia applying ice pieces and intraoperative frozen section evaluation of the mass: complete replication of open approach with advantages of minimally invasive surgery.


Abdullah Erdem Canda, Arif Ozkan, Emre Arpali, Ersin Koseoglu, Murat Can Kiremit, Yakup Kordan, Burak Kocak, Mevlana Derya Balbay, Tarik Esen

1566 related Products with: Robotic assisted partial nephrectomy with cold ischemia applying ice pieces and intraoperative frozen section evaluation of the mass: complete replication of open approach with advantages of minimally invasive surgery.

5 G50ul1ml50ul1ml0.1ml2ml

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#32782705   2020/07/01 To Up

Paraganglioma of the spermatic cord: report of one case and review of literature.

Extra-adrenal paraganglioma is rare, and occurs in the retroperitoneum, and head and neck. The incidence rate of paraganglioma in urogenital system is very low, especially in the spermatic cord. A case of paraganglioma of spermatic cord is reported and relevant literature is reviewed. A spermatic cord mass was found in the right scrotum in a middle-aged man 2 years ago, without hormone symptoms. Understanding of clinical and intraoperative frozen pathology was inadequate. Ultrasound images showed that there was abundant blood supply around the right spermatic cord with clear boundaries. The conventional pathology of the tumor presented a typical histologic morphology of paraganglioma. Immunohistochemistry showed that chief tumor cells were CGA (+), syn (+), CD56 (+), SDHB (+), and sertoli cells were S-100 (strong+). There are few reported cases at present, and the etiology and pathogenesis are not clear yet. The rapid frozen pathologic diagnosis during operation is very challenging, and it is easily diagnosed by routine histology combined with immunohistochemistry. Gene detection is recommended if necessary. Early diagnosis is helpful to the choice of operation mode and the prevention and control of intraoperative risk.
Di Sun, Ping Yang, Ying Liu, Suxia Wang

1568 related Products with: Paraganglioma of the spermatic cord: report of one case and review of literature.

5 G

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#32782529   2020/07/01 To Up

Effect of and mutations on the prognosis of patients with synchronous metastatic colorectal cancer presenting with liver-only and lung-only metastases.

It has been reported that 20-25% of patients with colorectal cancer (CRC) have metastases at the time of diagnosis. Liver and lung are the most common metastatic sites. The aim of the present study was to investigate the association of and mutations with clinicopathological features and prognosis of patients with initial liver-metastasis only (LiM-only) or lung-metastasis only (LuM-only) metastatic CRC (mCRC). Overall, 166 patients with CRC with initial LiM-only (n=124) and LuM-only (n=42) were retrospectively analyzed from January 2014 to December 2017. The median follow-up time was 19.2 months (1.0-57.1 months). Patient characteristics at diagnosis were collected. Genomic DNA was isolated from frozen primary CRC tissues for targeting and . Patients with LuM-only were significantly older compared with those with LiM-only (65.5 vs. 61.5 years; P=0.05). There was no significant differences between the LiM-only and LuM-only groups in terms of sex, location of the primary tumor, serum carcinoembryonic antigen level, histological grade and mutation status. mutations were detected in 43 (41.0%) patients with LiM-only and 13 (35.1%) patients with LuM-only. The overall survival time (OS) of LuM-only was more favorable compared with that of patients with LiM-only (44.5 vs. 24.7 months); however, there was no significant difference (P=0.095). The progression-free survival (PFS) and OS in the wild-type group were significantly improved compared with the mutant cohorts (P=0.004 and P=0.031, respectively) in the LiM-only group. In patients with stage IV CRC, those with synchronous LiM-only mCRC had a higher incidence of metastasis but a less favorable PFS and OS compared with patients with LuM-only. mutation status exhibited a significant association with the survival outcome in patients with LiM-only mCRC.
Shih-Chang Chuang, Ching-Wen Huang, Yi-Ting Chen, Cheng-Jen Ma, Hsiang-Lin Tsai, Tsung-Kun Chang, Wei-Chih Su, Wen-Hung Hsu, Chao-Hung Kuo, Jaw-Yuan Wang

1034 related Products with: Effect of and mutations on the prognosis of patients with synchronous metastatic colorectal cancer presenting with liver-only and lung-only metastases.

100ul 5 G

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#32782312   2020/08/11 To Up

Clinical evaluation of fully automated molecular diagnostic system "Simprova" for influenza virus, respiratory syncytial virus, and human metapneumovirus.

Influenza virus, respiratory syncytial virus, and human metapneumovirus commonly cause acute upper and lower respiratory tract infections, especially in children and the elderly. Although rapid antigen detection tests for detecting these infections have been introduced recently, these are less sensitive than nucleic acid amplification tests. More recently, highly sensitive point-of-care testings (POCTs) have been developed based on nucleic acid amplification tests, which are easy to use in clinical settings. In this study, loop-mediated isothermal amplification (LAMP)-based POCT "Simprova" to detect influenza A and B viruses, respiratory syncytial virus, and human metapneumovirus was developed. Simprova system is fully automated and does not require skilled personnel. In addition, positive results can be achieved faster than with PCR. In this study, the accuracy of the POCT was retrospectively analyzed using 241 frozen stocked specimens. Additionally, the usability of the Simprova at clinical sites was assessed in a prospective clinical study using 380 clinical specimens and compared to those of real-time PCR and rapid antigen detection test. The novel LAMP-based POCT demonstrated high sensitivity and specificity in characterizing clinical specimens from patients with influenza-like illnesses. The Simprova is a powerful tool for early diagnosis of respiratory viral infections in point-of-care settings.
Ikuyo Takayama, Shohei Semba, Kota Yokono, Shinji Saito, Mina Nakauchi, Hideyuki Kubo, Atsushi Kaida, Masashi Shiomi, Akihiro Terada, Kiyotaka Murakami, Katsushi Kaji, Keiichi Kiya, Yoshitaka Sawada, Kunihiro Oba, Sadasaburo Asai, Toshihiro Yonekawa, Hidetoshi Watanabe, Yuji Segawa, Tsugunori Notomi, Tsutomu Kageyama

1899 related Products with: Clinical evaluation of fully automated molecular diagnostic system "Simprova" for influenza virus, respiratory syncytial virus, and human metapneumovirus.

100 μg11 mg15 100 10 2 5ug100 100 100

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#32782045   2020/08/12 To Up

Energy-dense, nutrient-poor food and beverage sales in Australia: where and when products are sold, and how sales are changing over time.

To quantify sales trends for key energy-dense, nutrient-poor (EDNP) foods and beverages over 5 years in Australia.
Emma Gearon, Devorah Riesenberg, Kathryn Backholer, Adrian J Cameron, Gary Sacks, Cliona Ni Mhurchu, Anna Peeters

1857 related Products with: Energy-dense, nutrient-poor food and beverage sales in Australia: where and when products are sold, and how sales are changing over time.

case1,000 tests200ug1 mg1000 tests200 100ug100ug25 mg2.5 mg100ul

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#32782017   2020/08/12 To Up

Recurrent small bowel obstruction caused by Burkitt lymphoma in an elderly man: a case report and review of the literature.

Acute small bowel obstruction is a common surgical emergency usually caused by abdominal adhesions, followed by intraluminal tumors from metastatic disease. Although lymphomas have been known to cause bowel obstruction, Burkitt lymphoma is seldom reported to induce an obstruction in the adult population.
Saro Kasparian, Ethan Burns, Ahmed Shehabeldin, Melina Awar, Sai Ravi Pingali

2043 related Products with: Recurrent small bowel obstruction caused by Burkitt lymphoma in an elderly man: a case report and review of the literature.



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#32781884   2020/08/12 To Up

Effect of antithrombin in fresh frozen plasma on hemostasis after cardiopulmonary bypass surgery.

Supplementation of fresh frozen plasma immediately after cardiopulmonary bypass is an effective method to enhance clotting ability as coagulation factors are consumed in the extracorporeal circuit during cardiopulmonary bypass. On the other hand, the anticoagulation factors in fresh frozen plasma can also deter the clotting ability. This study investigated the effect of fresh frozen plasma administration on the comprehensive clotting ability following cardiopulmonary bypass.
Kazuhiro Shirozu, Yuji Karashima, Ken Yamaura

1092 related Products with: Effect of antithrombin in fresh frozen plasma on hemostasis after cardiopulmonary bypass surgery.

1 mg0.1ml (1mg/ml)96T

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