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#35152272 
2022/02/12
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Exercise in advanced prostate cancer elevates myokine levels and suppresses in-vitro cell growth.
Altering the systemic milieu through exercise has been proposed as a potential mechanism underlying exercise-driven tumour suppression. It is not yet known whether men with advanced prostate cancer can elicit such adaptations following a program of exercise. The purpose is to examine myokine levels of serum acquired from metastatic castrate-resistant prostate cancer (mCRPC) patients recruited to the INTERVAL-GAP4 trial before and after 6 months of exercise and its tumour-suppressive effect.Jin-Soo Kim, Dennis R Taaffe, Daniel A Galvão, Nicolas H Hart, Elin Gray, Charles J Ryan, Stacey A Kenfield, Fred Saad, Robert U Newton