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#35045582   2022/01/19 To Up

Caries Risk Documentation And Prevention: eMeasures For Dental Electronic Health Records.

 Longitudinal patient level data available in the electronic health record (EHR) allows for the development, implementation, and validations of dental quality measures (eMeasures).
Suhasini Bangar, Ana Neumann, Joel M White, Alfa Yansane, Todd R Johnson, Gregory W Olson, Shwetha V Kumar, Krishna K Kookal, Aram Kim, Enihomo Obadan-Udoh, Elizabeth Mertz, Kristen Simmons, Joanna Mullins, Ryan Brandon, Muhammad F Walji, Elsbeth Kalenderian

2603 related Products with: Caries Risk Documentation And Prevention: eMeasures For Dental Electronic Health Records.

1 G100 ml0.1 mg500 2.5 mg100ug1,000 tests100ul20 ug10 mg

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#35045581   2022/01/19 To Up

New Isoquinoline Alkaloids from Paraphaeosphaeria sporulosa F03, a Fungal Endophyte Isolated from Paepalanthus planifolius.

As part of our continuing efforts to discover new bioactive compounds from endophytic fungal sources, we have investigated the extract of the F03 strain. The study led to the isolation of four new 3-methyl-isoquinoline alkaloids (1:  - 4: ) and four known polyketides (5:  - 8: ). The structures of compounds 1:  - 4: were elucidated by 1D and 2D NMR experiments and HRMS analysis. The absolute configuration of 4: was determined by comparison of its experimental electronic circular dichroism spectrum with calculated data. Compounds 1:  - 4: exhibited antifungal activity with minimal inhibitory concentration values ranging from 6.25 - 50 µg/mL against six species but they did not present any cytotoxic activity against the human tumor cell lines A549 (lung), MCF-7 (breast), and HepG2 (hepatocellular). In addition, compound 4: exhibited antiplasmodial activity in the low micromolar range (IC = 4 µM).
Marcelo R de Amorim, Tiago A Paz, Luciano da S Pinto, Felipe Hilário, Camila L Zanini, Anna Caroline C Aguiar, Débora E S Silva, Maysa Furlan, Rafael V C Guido, Taís M Bauab, Adelino V de G Netto, Lourdes C Dos Santos

1963 related Products with: New Isoquinoline Alkaloids from Paraphaeosphaeria sporulosa F03, a Fungal Endophyte Isolated from Paepalanthus planifolius.

50 ul100 mg25 mg 25 G1 mg250 mg5 mg100 ug 5 MG1 mg100 ul1 g

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#35045548   2022/01/17 To Up

Development of neutron-activated samarium-153-loaded polystyrene microspheres as a potential theranostic agent for hepatic radioembolization.

Hepatic radioembolization is an effective minimally invasive treatment for primary and metastatic liver cancers. Yttrium-90 [90Y]-labelled resin or glass beads are typically used as the radioembolic agent for this treatment; however, these are not readily available in many countries. In this study, novel samarium-153 oxide-loaded polystyrene ([153Sm]Sm2O3-PS) microspheres were developed as a potential alternative to 90Y microspheres for hepatic radioembolization.
Hun Yee Tan, Yin How Wong, Azahari Kasbollah, Mohammad Nazri Md Shah, Basri Johan Jeet Abdullah, Alan Christopher Perkins, Chai Hong Yeong

2031 related Products with: Development of neutron-activated samarium-153-loaded polystyrene microspheres as a potential theranostic agent for hepatic radioembolization.

10 plates96 Tests1 kit50 assays100 assays0.1ml (1mg/ml)1 kit100 plates1 kit

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#35045546   2022/01/17 To Up

Evaluation of fluorine-18-fluorodeoxyglucose PET/computed tomography and human epithelial growth factor receptor 2 expression in treatment-naive patients with lung adenocarcinoma.

Human epithelial growth factor receptor 2 (HER2) is overexpressed in several types of cancers. The correlation between tumor glucose activity and HER2 expression can vary. This study is a retrospective investigation of fluorine-18-fluorodeoxyglucose PET/computed tomography (18F-FDG PET/CT) and HER2 expression status in patients with lung adenocarcinoma.
Yuan Li, Xiaodong Wu, Juanjuan Fang, Qingping Zhao, Yan Huang, Lei Jiang

1290 related Products with: Evaluation of fluorine-18-fluorodeoxyglucose PET/computed tomography and human epithelial growth factor receptor 2 expression in treatment-naive patients with lung adenocarcinoma.

20ug2 Pieces/Box1 kit(96 Wells)10ug4 Membranes/Box100 μg100ug Lyophilized2ug96tests2 4 Sample Kit2ug

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[Short-Term Outcomes of Laparoscopic Surgery for Gallbladder Cancer-A Single Institutional Experience].

Laparoscopic surgery is a safe, minimally invasive, and effective approach in managing abdominal malignancies. Laparoscopic anatomical resection has been covered by insurance in Japan since 2016. Here, we have reported the short-term outcomes of gallbladder cancer in laparoscopic cholecystectomy, gallbladder bed resection, or S4a/S5 liver resection with lymph node dissection.
Yutaka Takeda, Yoshiaki Ohmura, Yoshiteru Katsura, Go Shinke, Yukari Kihara, Kengo Haruna, Hiroshi Kusafuka, Masaki Sakaue, Shinsuke Katsuyama, Kenji Kawai, Masayuki Hiraki, Toru Masuzawa, Atsushi Takeno, Taishi Hata, Kohei Murata

1961 related Products with: [Short-Term Outcomes of Laparoscopic Surgery for Gallbladder Cancer-A Single Institutional Experience].

100ug10 100 μg1 mg100 μg100 μg0.1 mg100 μg50

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#35045414   2022/01/19 To Up

A Homozygous Missense Variant in Hedgehog Acyltransferase (HHAT) Gene Associated with 46,XY Gonadal Dysgenesis.

Disorders of gonadal development represent a clinically and genetically heterogeneous group of DSD, and the etiology in many cases remains unknown, indicating that our knowledge of factors controlling sex determination is still limited.
Inas Mazen, Alaa Kamel, Kenneth McElreavey, Anu Bashamboo, Aya Elaidy, Mohamed S Abdel-Hamid

2587 related Products with: A Homozygous Missense Variant in Hedgehog Acyltransferase (HHAT) Gene Associated with 46,XY Gonadal Dysgenesis.

100ug100.00 ug300 units100.00 ug1 Set100ug Lyophilized1 Set1 Set100 μg1 Set100 μg50 ug

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#35045384   2022/01/16 To Up

Association of short-term exposure to air pollution with recurrent ischemic cerebrovascular events in older adults.

The acute effects of ambient air pollution on recurrence of ischemic cerebrovascular events (ICEs) remains largely unknown. We therefore conducted a time-stratified case-crossover study of 43,896 patients who were 60 years or older and were admitted to hospital for recurrent ICEs including ischemic stroke and transient ischemic attack in Guangzhou, China during 2016-2019. Based on each patient's home address and pollutant data from its neighboring air quality monitoring stations, we used an inverse distance weighting method to assess exposures to particulate matter with an aerodynamic diameter ≤2.5 μm (PM), particulate matter with an aerodynamic diameter ≤10 μm (PM), sulfur dioxide (SO), nitrogen dioxide (NO), carbon monoxide (CO) and ozone (O). Conditional logistic regression models were used to quantify exposure-response associations. During the study period, there were 43,896 case days and 149,131 control days. In single-pollutant models, each 10 μg/m increase in exposure to PM, NO and CO (mean exposure on date of admission and 1 day prior) was significantly associated with a 0.74% (95% confidence interval [CI]: 0.13-1.36%), 2.15% (1.38-2.93%) and 0.14% (0.07-0.21%) increase in odds of hospital admissions for recurrent ICEs, respectively, and no significant departures from linearity were detected. The association for NO exposure remained consistent in 2-pollutant models, while the associations for PM and CO disappeared or changed materially with adjustment for other pollutants. Stronger association for NO exposure was observed in cool season than that in warm season. We found that short-term exposure to ambient air pollutants, especially NO, was associated with increased risk of hospital admissions for recurrent ICEs in older adults.
Ruijun Xu, Qi Tian, Wenfeng Lu, Zhengyu Yang, Yunshao Ye, Yingxin Li, Qiaoxuan Lin, Yaqi Wang, Zhaoyu Fan, Tingting Liu, Luxi Xu, Xu Chen, Chunxiang Shi, Yun Zhou, Yuewei Liu

1673 related Products with: Association of short-term exposure to air pollution with recurrent ischemic cerebrovascular events in older adults.

100 100 μg100 μg 0.1 mg 100 μg100 μg100 50 1 mg100 μg100 μg

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#35045380   2021/12/07 To Up

Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease.

Abnormally phosphorylated tau, an indicator of Alzheimer's disease, accumulates in the first decades of life in the locus coeruleus (LC), the brain's main noradrenaline supply. However, technical challenges in in-vivo assessments have impeded research into the role of the LC in Alzheimer's disease. We studied participants with or known to be at-risk for mutations in genes causing autosomal-dominant Alzheimer's disease (ADAD) with early onset, providing a unique window into the pathogenesis of Alzheimer's largely disentangled from age-related factors. Using high-resolution MRI and tau PET, we found lower rostral LC integrity in symptomatic participants. LC integrity was associated with individual differences in tau burden and memory decline. Post-mortem analyses in a separate set of carriers of the same mutation confirmed substantial neuronal loss in the LC. Our findings link LC degeneration to tau burden and memory in Alzheimer's, and highlight a role of the noradrenergic system in this neurodegenerative disease.
Martin J Dahl, Mara Mather, Markus Werkle-Bergner, Briana L Kennedy, Samuel Guzman, Kyle Hurth, Carol A Miller, Yuchuan Qiao, Yonggang Shi, Helena C Chui, John M Ringman

2378 related Products with: Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease.

96 tests96T96 tests96 tests96 tests50ul (1mg/ml)2 Pieces/Box

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