Search results for: ApoBrdU DNA Fragmentation Assay Kit
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Diosgenin induces apoptosis in HeLa cells via activation of caspase pathway.
To investigate the mechanism of diosgenin-induced HeLa cell apoptosis.Rui Hou, Qiu-Li Zhou, Ben-Xiang Wang, Shin-Ichi Tashiro, Satoshi Onodera, Takashi Ikejima
2627 related Products with: Diosgenin induces apoptosis in HeLa cells via activation of caspase pathway.
2 Pieces/Box2 Pieces/Box1.5 x 10^6 cells5 mg100ul20 ul100 ul (2 mM)2 Pieces/Box100 100 2 Pieces/Box100 μg
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Ubiquitin-proteasome inhibitor enhances tumour necrosis factor-alpha-induced apoptosis in rat gastric epithelial cells.
Tumour necrosis factor (TNF-alpha) is a candidate factor for involvement in inflammation-mediated gastric mucosal injury. However, the effect of this cytokine on gastric epithelial cells has been poorly investigated. In the present study, we examined whether gastric epithelial cells are resistant to TNF-alpha-induced apoptosis, and whether this resistance is related to ubiquitin-proteasome-associated nuclear factor-kappaB (NF-kappaB) activation.Y Naito, O Handa, T Takagi, T Ishikawa, E Imamoto, S Nakagawa, T Yamaguchi, N Yoshida, H Matsui, T Yoshikawa
2856 related Products with: Ubiquitin-proteasome inhibitor enhances tumour necrosis factor-alpha-induced apoptosis in rat gastric epithelial cells.
100ug Lyophilized1 kit(96 Wells)100ug Lyophilized10 100 ug5mg100ug Lyophilized100ug Lyophilized100ug Lyophilized5 1 mg
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Anticancer effect of PMEDAP--monitoring of apoptosis.
Antitumor effect of N-9-[2-(phosphonomethoxy) ethyl]-2,6-diaminopurine (PMEDAP) was studied in an in vivo model of s.c. transplanted Sprague-Dawley (SD/cub) rat T-cell lymphomas. Three individual SD/cub neoplasias (SD10/96, SD14/97, SD1/90) of different phenotypes were used. During the treatment, survival of the rats, increase of lymphoma mass, and DNA fragmentation detected by APO/BRDU kit, as well as Bcl2 and p53 protein expression, were followed. The study gives evidence of the positive therapeutic effect of PMEDAP in two of the three tested lymphomas, SD10/96 and SD14/97. Slowly growing SD1/90 lymphoma differs from the others in a uniform karyotype with trisomy of chromosome 11, CD4- immunophenotype, heterogeneous cellular morphology and constitutive expression of p53 protein found in some neoplastic cells. Thus, the diverse anticancer efficacy of PMEDAP treatment among SD/cub lymphomas could be associated with the different phenotypes of individual neoplasias.K Bobková, B Otová, I Marinov, V Mandys, A Panczak, I Votruba, A Holý