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Lower disease activity but higher risk of severe COVID-19 and herpes zoster in patients with systemic lupus erythematosus with pre-existing autoantibodies neutralising IFN-α.
Type-I interferons (IFNs-I) have potent antiviral effects. IFNs-I are also overproduced in patients with systemic lupus erythematosus (SLE). Autoantibodies (AAbs) neutralising IFN-α, IFN-β and/or IFN-Ï subtypes are strong determinants of hypoxemic COVID-19 pneumonia, but their impact on inflammation remains unknown.Alexis Mathian, Paul Breillat, Karim Dorgham, Paul Bastard, Caroline Charre, Raphael Lhote, Paul Quentric, Quentin Moyon, Alice-Andrée Mariaggi, Suzanne Mouries-Martin, Clara Mellot, François Anna, Julien Haroche, Fleur Cohen-Aubart, Delphine Sterlin, Noël Zahr, Adrian Gervais, Tom Le Voyer, Lucy Bizien, Quentin Amiot, Micheline Pha, Miguel Hié, Francois Chasset, Hans Yssel, Makoto Miyara, Pierre Charneau, Pascale Ghillani-Dalbin, Jean-Laurent Casanova, Flore Rozenberg, Zahir Amoura, Guy Gorochov
2471 related Products with: Lower disease activity but higher risk of severe COVID-19 and herpes zoster in patients with systemic lupus erythematosus with pre-existing autoantibodies neutralising IFN-α.
100 g48 assays 500 tests25 mg25 mg96 tests400Tests1-99 mg/ml/ea price x 2
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A simple Preheating-pyrolysis Strategy Leading to Superior ORR Activity in Fe-N/Carbon black.
MChen Ouyang, Lirong Zheng, Qinghua Zhang, Xun Wang
1612 related Products with: A simple Preheating-pyrolysis Strategy Leading to Superior ORR Activity in Fe-N/Carbon black.
1 kit1 kit96 assays 100 48 assays 400Tests0.1ml (1mg/ml)96 assays 100
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Deep eutectic solvent with Lewis acid for highly efficient biohydrogen production from corn straw.
To boost saccharification and biohydrogen production efficiency from corn straw, Lewis acid enhanced deep eutectic solvent (DES) pretreatment using choline chloride/glycerol was developed. A notable enhancement of the enzymatic hydrolysis efficiency from 26.3% to 87.0% was acquired when corn straw was pretreated with aqueous DES at 100 C for 5 h using 2.0 wt% AlCl. A maximum biohydrogen yield of 114.8 mL/g total solids (TS) was achieved in the sequential dark fermentation stage, which was 2.1 times higher than that of the raw feedstock (37.1 mL/g TS). The enhanced efficient conversion was ascribed to the effective removal of lignin and hemicellulose, which led to the bio-accessibility of the straw. This work provides new sights for the rational design of efficient AlCl-aided aqueous DES system toward biohydrogen production from lignocellulosic biomass.Xue Chen, Jungang Jiang, Jiubin Zhu, Wenlu Song, Chuantao Liu, Ling-Ping Xiao