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Antioxidant activity and potential ameliorating effective ingredients for high altitude-induced fatigue from Gansu Maxianhao (Pedicularis Kansuensis Maxim.).To investigate the antioxidant property and potential ameliorating effective ingredients for high altitude-induced fatigue from Gansu Maxianhao (Pedicularis Kansuensis Maxim.).
2853 related Products with: Antioxidant activity and potential ameliorating effective ingredients for high altitude-induced fatigue from Gansu Maxianhao (Pedicularis Kansuensis Maxim.).
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[The role of adipose tissue and laboratory predictors of primary osteoporosis.]The purpose of this work was to determine the information content of alkaline phosphatase (ALP), total calcium (Ca) as predictors for the diagnosis of osteoporosis. By laboratory methods, 2451 people were divided into two groups according to the presence/absence of metabolic syndrome (MetS+ / MetS-): 1946 women (MetS- 1119, MetS+ 827) and 505 men (MetS- 264, MetS+ 241). Patients with laboratory signs of liver pathology are excluded. In women: MetS+ levels of ALP and Ca significantly differ from MetS- (p<0.0001), no differences were found for men. ALP synchronously change the indicators of TG, HDL, LDL, ALT, AST, Ca, demonstrating a positive relationship (p<0.001), the indicators do not exceed the threshold values. MetS- women in pre- and postmenopausal women significantly differ in ALP: 63.90 E / l vs 79.10 E / l (p<0.0001).
1703 related Products with: [The role of adipose tissue and laboratory predictors of primary osteoporosis.]FDA Standard Frozen Tissu Adipose tissue disease sp High density (69 cases 20 Breast cancer tissue arra Normal rat multiple organ Leptin ELISA Kit, Human A Tissue array of ovarian g FDA Standard Frozen Tissu Normal mouse multiple org FDA Standard Frozen Tissu Normal rat multiple organ FDA Standard Frozen Tissu
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Triflumuron induces cytotoxic effects on hepatic and renal human cell lines.Insect growth regulator insecticides are a new class of pesticides, commonly used around the world to control insect damages. Among those compounds, we focused our interest on triflumuron (TFM), which is less toxic than other conventional insecticides. However, not much is known about its toxic effects on mammalian systems. Therefore, our study aimed toward evaluating the cytotoxic and genotoxic effects of TFM using two different cell lines, the human renal embryonic cells (HEK 293) and hepatocytes (Hep G2). We showed, according to the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, that TFM reduced significantly the cell viability and increased the reactive oxygen species generation, malondialdehyde levels, and mitochondrial membrane potential in both cell lines. The antioxidant system was disturbed as assessed by the increased activities in both catalase and superoxide dismutase. We demonstrated also, that TFM is an inductor of DNA damages quantified by the comet assay. Moreover, we showed an overexpression of proapoptotic Bax and a decrease in antiapoptotic Bcl-2 expression. As a conclusion, we demonstrate that the liver presents the major target organ to TFM, in which the cytotoxicity and the genotoxic effects were significantly higher in hepatic cells than in renal cells and by consequence its uses must be controlled.
1446 related Products with: Triflumuron induces cytotoxic effects on hepatic and renal human cell lines.Human tumor cell array, 1 Human tumor cell array, 1 Recombinant Human THPO [f Recombinant Human T-cell GFP Expressing Human Brai Screen Quest™ Fluo 8 Me GFP Expressing Human Aort Human vascular cell adhes Astra Blue 6GLL, Stain fo Human, Clara Cell Protein Cal-520™ PBX Calcium As RFP Expressing Human Reti
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