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#36183004   2022/10/01 To Up

Perfused boundary region as biomarker for endothelial integrity in former preterms in adolescence.

Extremely low birth weight (ELBW) survivors have microvascular structural differences already described in kidney and retina, suggesting changes in endothelial integrity. A biomarker of endothelial integrity is perfused boundary region (PBR), which measures glycocalycal thickness. The endothelial glycocalyx is a complex, highly versatile structure with essential roles in vascular integrity and function. We explored PBR patterns together with other microvascular markers in healthy controls and former ELBW children.
Liselotte Van Loo, Karel Allegaert, Elena Levtchenko, Zhenyu Zhang, Jan A Staessen, Anke Raaijmakers

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