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#32650324   2020/07/10 To Up

Biofabrication of endothelial cell, dermal fibroblast, and multilayered keratinocyte layers for skin tissue engineering.

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Natan Barros, Hanjun Kim, Marcus J Goudie, KangJu Lee, Praveen Bandaru, Ethan A Banton, Einollah Sarikhani, Wujin Sun, Shiming Zhang, Hyun-Jong Cho, Martin C Hartel, Serge Ostrovidov, Samad Ahadian, Saber Hussain, Nureddin Ashammakhi, Mehmet R Dokmeci, Rondinelli Donizetti Herculano, Junmin Lee, Ali Khademhosseini

1450 related Products with: Biofabrication of endothelial cell, dermal fibroblast, and multilayered keratinocyte layers for skin tissue engineering.

50 assays

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#32650320   2020/07/10 To Up

Amplitude versus spatially modulated electrotactile feedback for myoelectric control of two degrees of freedom.

Artificial proprioceptive feedback from a myoelectric prosthesis is an important aspect in enhancing embodiment and user satisfaction, possibly lowering the demand for visual attention while controlling a prosthesis in everyday tasks. Contemporary myoelectric prostheses are advanced mechatronic systems with multiple degrees of freedom, and therefore, to communicate the prosthesis state, the feedback interface needs to transmit several variables simultaneously. In the present study, two different configurations for conveying proprioceptive information of wrist rotation and hand aperture through multichannel electrotactile stimulation were developed and evaluated during online myoelectric control.
Martin Alexander Garenfeld, Christian Korfitz Mortensen, Matija Štrbac, Jakob L Dideriksen, Strahinja Dosen

1854 related Products with: Amplitude versus spatially modulated electrotactile feedback for myoelectric control of two degrees of freedom.

5 G 1 G100 Tests2.50 nmol 25 G100ug Lyophilized96 tests 0.1 mg

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#32650305   2020/07/10 To Up

Self-reported symptoms of SARS-CoV-2 infection in a non-hospitalized population: results from the large Italian web-based EPICOVID19 cross-sectional survey.

Understanding the occurrence of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)-like symptoms in a large non-hospitalized population, when the epidemic peak was occurring in Italy, is of paramount importance but data are scarce.
Fulvio Adorni, Federica Prinelli, Fabrizio Bianchi, Andrea Giacomelli, Gabriele Pagani, Dario Bernacchia, Stefano Rusconi, Stefania Maggi, Caterina Trevisan, Marianna Noale, Sabrina Molinaro, Luca Bastiani, Loredana Fortunato, Nithiya Jesuthasan, Aleksandra Sojic, Carla Pettenati, Marcello Tavio, Massimo Andreoni, Claudio Mastroianni, Raffaele Antonelli Incalzi, Massimo Galli

2996 related Products with: Self-reported symptoms of SARS-CoV-2 infection in a non-hospitalized population: results from the large Italian web-based EPICOVID19 cross-sectional survey.

250ul1x107 IFU/ml x 200ul50 mg200ul100ug Lyophilized

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#32650284   2020/06/08 To Up

Modest Clostridiodes difficile infection prediction using machine learning models in a tertiary care hospital.

Previous studies have shown promising results of machine learning (ML) models for predicting health outcomes. We develop and test ML models for predicting Clostridioides difficile infection (CDI) in hospitalized patients. This is a retrospective cohort study conducted during 2015-2017. All inpatients tested for C. difficile were included. CDI was defined as having a positive glutamate dehydrogenase and toxin results. We restricted analyses to the first record of C. difficile testing per patient. Of 3514 patients tested, 136 (4%) had CDI. Age and antibiotic use within 90 days before C. difficile testing were associated with CDI (P < 0.01). We tested 10 ML methods with and without resampling. Logistic regression, random forest and naïve Bayes models yielded the highest AUC ROC performance: 0.6. Predicting CDI was difficult in our cohort of patients tested for CDI. Multiple ML models yielded only modest results in a real-world population of hospitalized patients tested for CDI.
Alexandre R Marra, Mohammed Alzunitan, Oluchi Abosi, Michael B Edmond, W Nick Street, John W Cromwell, Jorge L Salinas

1689 related Products with: Modest Clostridiodes difficile infection prediction using machine learning models in a tertiary care hospital.

100 μg100 μg100 μg100.00 ug100 μg100 μg

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#32650280   2020/06/29 To Up

Structural brain differences in pre-adolescents who persist in and recover from stuttering.

Stuttering is a complex speech fluency disorder occurring in childhood. In young children, stuttering has been associated with speech-related auditory and motor areas of the brain. During transition into adolescence, the majority of children who stutter (75-80%) will experience remission of their symptoms. The current study evaluated brain (micro-)structural differences between pre-adolescents who persisted in stuttering, those who recovered, and fluently speaking controls.
S P C Koenraads, M P van der Schroeff, G van Ingen, S Lamballais, H Tiemeier, R J Baatenburg de Jong, T White, M C Franken, R L Muetzel

2998 related Products with: Structural brain differences in pre-adolescents who persist in and recover from stuttering.

96 tests96 tests100 μg 50 UG50ug

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#32650245   2020/07/02 To Up

A novel AIE active NIR fluorophore based triphenylamine for sensing of Hg and CN and its multiple application.

New strategies still need to be proposed that can be used to sense and remove toxic environmental pollutants in a sensing system. In this research, a novel NIR fluorescence sensor 1 was designed and prepared with aggregation induced emission (AIE) property. The fluorescence intensity of the sensor 1 in DMSO/HO mixed solvent was changed along with the proportion of water. The sensor 1 can be successfully used for real-time detection and removal of Hg in 20% DMSO aqueous solution with high selectivity, quick response and so on. Furthermore it can be efficiently reused and recycled without any loss through NaS. In addition, the sensor 1 displayed high sensitivity and selectivity to cyanide ions in 1% DMSO aqueous solution with the presence of other interference anions. The sensing mechanism for Hg and cyanide ion was evaluated by H NMR spectra, Mass spectrometry. The sensor 1 exhibited low cytotoxicity for biological applications, which was used as an outstanding fluorescent transducer for detection of cyanide ion in living cells. Based on the visible fluorescence change for the sensor 1 to cyanide ion, the measurement was performed for food materials containing cyanide, such as potato, cassava powder and almond. This research provides perspective potential in solving the problem of other pollution and stimulating new thinking for designing of the novel fluorescence materials.
Xiaoye Wen, Li Yan, Zhefeng Fan

2493 related Products with: A novel AIE active NIR fluorophore based triphenylamine for sensing of Hg and CN and its multiple application.

1,000 tests100ug1 mg1000 tests100ul1 ml100 mg100ug

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#32650235   2020/06/12 To Up

Emerging Function and Clinical Significance of Exosomal circRNAs in Cancer.

Exosomes are a type of extracellular vesicles (EVs) secreted by almost all cells, with a diameter range of 30-150 nm and a lipid bilayer membrane. Exosomes are now considered as vital mediators of intercellular communication and participate in multiple cellular processes, such as signal transduction and antigen presentation. Recently, circular RNAs (circRNAs), a novel class of noncoding RNAs (ncRNAs), have been found to be abundant and stable in exosomes. Increasing evidence indicates that exosome-derived circRNAs act as signaling molecules to regulate cancer growth, angiogenesis, invasion, metastasis, and sensitivity to chemotherapy. Moreover, circulating exosomal circRNAs can reflect the progression and malignant characteristics of cancer, implying their great potential as promising, non-invasive biomarkers for cancer diagnosis and prognosis. In this review, we summarize the recent progress on the functional roles of exosomal circRNAs in cancer progression, discussing their potential as promising biomarkers and therapeutic targets in cancer. Comprehensive elucidation of molecular mechanisms relevant to the implications of exosomal circRNAs in cancer progression will be conducive to the development of innovative diagnostic and therapeutic approaches in cancer.
Man Wang, Fei Yu, Peifeng Li, Kun Wang

1193 related Products with: Emerging Function and Clinical Significance of Exosomal circRNAs in Cancer.



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#32650228   2020/07/07 To Up

Is South Africa being spared the global opioid crisis? A review of trends in drug treatment demand for heroin, nyaope and codeine-related medicines in South Africa (2012-2017).

South Africa has seen a sharp increase in treatment admission trends for opioids despite beliefs that rates of opioid use remain low and do not represent a major problem. To advocate for the extension of Opioid Use Disorder (OUD) treatment and harm minimisation services in South Africa, better estimates of the extent of opioid use is needed. This paper responds to this need by describing (i) trends in treatment utilization for opioid-related problems in South Africa and (ii) differences in the profile of patients accessing treatment for different classes of opioids - heroin, 'nyaope' and codeine use.
Nadine Harker, Warren Covelé Lucas, Ria Laubscher, Siphokazi Dada, Bronwyn Myers, Charles Dh Parry

2768 related Products with: Is South Africa being spared the global opioid crisis? A review of trends in drug treatment demand for heroin, nyaope and codeine-related medicines in South Africa (2012-2017).

100ug Lyophilized100ug Lyophilized100ug Lyophilized100 ul100 assays100ug Lyophilized100ug Lyophilized100ug Lyophilized100ug Lyophilized100 μg0.1ml

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#32650221   2020/07/01 To Up

Incremental validity of coronaphobia: Coronavirus anxiety explains depression, generalized anxiety, and death anxiety.

The adverse psychological effects of COVID-19 have increased globally. Moreover, the psychological toll may be worsening for this health crisis due to the growing numbers of mass deaths and unemployment levels. Coronaphobia, a relatively new pandemic-related construct, has been shown to be strongly related to functional impairment and psychological distress. However, the extent to which coronaphobia is uniquely accountable for the psychological distress experienced during the COVID-19 crisis has not been systematically investigated. The current study examined this question of incremental validity using online data from 453 adult MTurk workers in the U.S. The results of a series of hierarchical multiple regression analyses demonstrated that coronaphobia explained additional variance in depression, generalized anxiety, and death anxiety, above sociodemographics, COVID-19 factors, and the vulnerability factors of neuroticism, health anxiety, and reassurance-seeking behaviors. These findings suggest that health professionals should be aware of coronaphobia as this expression of pandemic-related stress has reliably demonstrated incremental validity in accounting for major indicators of psychological distress.
Sherman A Lee, Mary C Jobe, Amanda A Mathis, Jeffrey A Gibbons

1523 related Products with: Incremental validity of coronaphobia: Coronavirus anxiety explains depression, generalized anxiety, and death anxiety.

10 mg100ug Lyophilized100 ug/vial1000 tests100ug100 100ug100ug Lyophilized100ug Lyophilized25 mg0.2 mg100 µg

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