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#33657694   // To Up

[Clinical characteristics and risk factors of post polypectomy electrocoagulation syndrome in children].

To study the clinical characteristics and risk factors of post polypectomy electrocoagulation syndrome (PPECS) in children. Clinical data of 23 children with PPECS in Children's Hospital Affiliated to Zhengzhou University from January 2015 to December 2019 were retrospectively analyzed. Additionally, 115 children without PPECS who had polypectomy performed by the same endoscopist at the same time were collected into the control group. The morbidity, clinical characteristics and therapeutic protocol were analyzed, and the risk factors of PPECS were analyzed by Logistic regression. Among the total 2 083 children who had endoscopic polypectomy with electrocautery, 23 children (1.1%) developed PPECS. All had abdominal pain and fever. The average age of the children with PPECS was (3.5±1.5) years, including 19 cases (82.6%) younger than 3 years. There were 18 cases with polyps larger than 25 mm (78.3%). The endoscopic operation time ((56±15) (24±8) min, =18.086, 0.01), the rate of piecemeal resection (78.3% (18/23) 17.4% (20/115), =17.358, 0.01), the lesion size ((38.4±3.7) . (15.8±4.3) mm, =15.127, <0.01), the proportion of polyps located in the right hemicolon (47.8% (11/23) 23.5% (27/115), =7.035, 0.05), and the proportion of broad-based polyps (78.3% (18/23) 25.2% (29/115), = 29.259, 0.01) in the PPECS group were all significantly higher than those in the non-PPECS group. Similarly, the leukocyte counts ((17.4±4.5)×10/L (8.5±1.2)×10/L, =6.085, 0.05) and C-reactive protein ((25.8±3.6) (1.1±0.6) mg/L, =5.531, 0.05) in the PPECS group were higher than those in the non-PPECS group. The results of multivariate Logistic regression analysis indicated that lesion size ≥25 mm (=7.554, 95% 3.135-20.158, 0.001), broad-based polyps (=5.676, 95% 1.153-9.596, 0.002) and lesion located in the right hemicolon (=5.845, 95% 1.737-9.297, 0.008) were independent risk factors of PPECS. The clinical features of PPECS in children are fever, abdominal pain and leukocytosis after the procedure. The lesion size ≥ 25 mm, broad-based polyps and lesion located in the right hemicolon are the independent risk factors of pediatric PPECS.
Y S Wang, J Zhang, X Q Li, Z D Yu, F Zhou

1955 related Products with: [Clinical characteristics and risk factors of post polypectomy electrocoagulation syndrome in children].



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#33657670   2021/03/03 To Up

Lnc-RNA LINC01279 induces endometriosis via targeting of HOXA10.

To explore the regulatory role and molecular mechanism of lncRNA-LINC01279 in endometriosis (EMs).
Liling Liu, Junping Cheng, Fu Wei, Lihong Pang, Zhifu Zhi, Wenmei Yang, Weihong Tan

2057 related Products with: Lnc-RNA LINC01279 induces endometriosis via targeting of HOXA10.

1mg/vial100 μg250ul25μg/vial100ug/vial10 nmol100μg/vial100ug/vial5 X 1000 U100 μg1000pcs100 ug/vial

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#33657669   2021/03/03 To Up

Generation of novel self-incompatible Brassica napus by CRISPR/Cas9.

Self-incompatibility (SI) is a genetic mechanism that prevents inbreeding in hermaphrodite angiosperms via the rejection of self-pollen. SI lines facilitate the utilization of heterosis (De Nettancourt 2001). In cruciferous plants, SI is determined by the S locus, which harbors genes encoding the stigma papilla cell-specific S-receptor kinase (SRK) and the pollen surface-localized ligand of SRK, S-locus cysteine-rich protein/S-locus protein 11 (SCR/SP11) (Schopfer et al., 1999; Suzuki et al., 1999).
Shengwei Dou, Tong Zhang, Jinxing Tu, Jinxiong Shen, Bin Yi, Jing Wen, Tingdong Fu, Cheng Dai, Chaozhi Ma

1207 related Products with: Generation of novel self-incompatible Brassica napus by CRISPR/Cas9.

96 Samples 5 G200ul

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#33657666   2021/03/03 To Up

Low androgen status inhibits erectile function by increasing pyroptosis in rat corpus cavernosum.

The mechanism of erectile dysfunction (ED) caused by low androgen status is not fully understood.
Zhi-Bin Chen, Ge Li, Haocheng Lin, Jun Jiang, Rui Jiang

2922 related Products with: Low androgen status inhibits erectile function by increasing pyroptosis in rat corpus cavernosum.

100 UG1 Set1 Set4/120 Packing /sleeve/bo20ug 1 G25 100 μg

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#33657658   2021/03/03 To Up

Calponin and MUC6 complement inhibin as diagnostic immunomarkers of serous cystadenoma in endoscopic ultrasound guided aspiration/biopsy specimens.

Because serous cystadenoma (SCA) does not usually require excision, it is critical to distinguish it from differential diagnoses which do, especially neuroendocrine tumour (NET). The gold standard for diagnosing SCA is assessment of endoscopic ultrasound guided fine needle aspiration/biopsy (EUS-FNAB) material. Inhibin immunohistochemistry aids this assessment but such positivity is not absolutely sensitive or specific to SCA. The following is the largest known study of SCA EUS-FNAB specimens and the first to compare four potential SCA immunomarkers between themselves and inhibin, as compared against NET.
Newton A C S Wong, Sophie Beavers, Pelvender Gill, Andrew Heryet, Josep Linares

1153 related Products with: Calponin and MUC6 complement inhibin as diagnostic immunomarkers of serous cystadenoma in endoscopic ultrasound guided aspiration/biopsy specimens.

96 assays 20 µl (10 mM)1mg24 tests100 assays100 μg100 assays1 kit10 96 samples

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#33657647   2021/03/03 To Up

Regeneration of pulp-dentine complex-like tissue in a rat experimental model under an inflammatory microenvironment using high phosphorous-containing bioactive glasses.

To investigate the effects of a bioactive glass with a high proportion of phosphorus (BG-hP) on the repair and regeneration of dental pulps in rats under an inflammatory microenvironment.
J Li, S Wang, Y Dong

1435 related Products with: Regeneration of pulp-dentine complex-like tissue in a rat experimental model under an inflammatory microenvironment using high phosphorous-containing bioactive glasses.

2 Pieces/Box4 Membranes/Box2 Pieces/Box 100 UG4 Arrays/Slide

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#33657581   2021/03/01 To Up

Upregulation of miR-29a suppressed the migration and invasion of trophoblasts by directly targeting LOXL2 in preeclampsia.

Preeclampsia is a pregnancy-specific disorder that is a major cause of maternal and foetal morbidity and mortality, with a prevalence of 6-8% of pregnancies. Although the downregulation of lysyl oxidase (LOX) and LOX-like protein 2 (LOXL2), which leads to reduced trophoblast cell migration and invasion through activation of the TGF-β1/Smad3/collagen pathway, is relevant to preeclampsia, the mechanisms regulating differences in the gene expression of LOX and LOXL2 in placentas are not yet understood. This study aimed to investigate the mechanisms regulating differences in the gene expression of LOX and LOXL2 in placentas.
Xiang-Hong Xu, Lin-Chen Tang, Fan Hao, Li-Ping Jin

1945 related Products with: Upregulation of miR-29a suppressed the migration and invasion of trophoblasts by directly targeting LOXL2 in preeclampsia.

5ug24 tests96 samples124 tests96 samples

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#33657579   2021/03/03 To Up

Effect of potassium on DNA methylation of aldosterone synthase gene.

Aldosterone synthase gene, CYP11B2 is regulated by potassium and angiotensin II (Ang II). We have reported that Ang II could change the DNA methylation status around transcription factor-binding sites and a transcription start site (TSS) and activate expression of CYP11B2. Similar to Ang II, small increases in extracellular potassium levels also increase CYP11B2 mRNA levels.
Yoshimichi Takeda, Masashi Demura, Fen Wang, Shigehiro Karashima, Takashi Yoneda, Mitsuhiro Kometani, Daisuke Aomo, Atsushi Hashimoto, Shin-Ichi Horike, Makiko Meguro-Horike, Yoshiyu Takeda

2071 related Products with: Effect of potassium on DNA methylation of aldosterone synthase gene.

300 units 5 G 6 ml Ready-to-use 50 ug96tests 25 MG50 ug100ug 1KG50 ug50 ug20

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#33657559   2021/03/03 To Up

The Role of Ninjurin1 and Its Impact beyond the Nervous System.

Ninjurin1 (Ninj1) is a double-transmembrane cell surface protein that could promote nerve regeneration in the process of the peripheral nervous system injury and repairment. Nonetheless, the accurate function of Ninj1 in the central nervous system and outside the nervous system is not completely clear. According to the recent studies, we found that Ninj1 is also aberrantly expressed in various pathophysiological processes in vivo, including inflammation, tumorigenesis, and vascular, bone, and muscle homeostasis. These findings suggest that Ninj1 may play an influential role during these pathophysiological processes. Our review summarizes the diverse roles of Ninj1 in multiple pathophysiological processes inside and outside the nervous system. Ninj1 should be considered as an important and novel therapeutic target in certain diseases, such as inflammatory diseases and ischemic diseases. Our study provided a better understanding of Ninj1 in different pathophysiological processes and thereby provided the theoretical support for further research.
Ke Liu, Yong Wang, Hongge Li

1012 related Products with: The Role of Ninjurin1 and Its Impact beyond the Nervous System.

50 UG 50 UGmin 2 cartons100.00 ul200 units 100 G11500 Units

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