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#33098750   2020/10/24 To Up

Brachyury engineers cardiac repair competent stem cells.

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Mark Li, Satsuki Yamada, Ao Shi, Raman Deep Singh, Tyler J Rolland, Ryounghoon Jeon, Natalia Lopez, Lukas Shelerud, Andre Terzic, Atta Behfar

2877 related Products with: Brachyury engineers cardiac repair competent stem cells.

5 x 10A5 cells/vial10 x 50ul/Unit11 Plate of 96 x 20ul/Unit10 ug1 x 10^6 cells/vial5 x 200ul/Unit100|uI x 10 vials5 x 200ul/Unit100ìl x 10 vials75 x 50ul/Unit10 rxns

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#33098743   2020/10/24 To Up

Biological fluid levels of iron and iron-related proteins in parkinson's disease: Review and meta-analysis.

The present systematic review and meta-analysis try to establish the cerebrospinal fluid (CSF) and serum/plasma levels of iron and iron-related proteins (ferritin, transferrin, lactoferrin, haptoglobin, and hepcidine) levels, and the urine levels of iron, in patients with Parkinson's disease (PD).
Félix Javier Jiménez-Jiménez, Hortensia Alonso-Navarro, Elena García-Martín, José A G Agúndez

2569 related Products with: Biological fluid levels of iron and iron-related proteins in parkinson's disease: Review and meta-analysis.

2 Pieces/Box2 Pieces/Box 1KG1096 tests 100 Slides 96T

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#33098731   2020/10/24 To Up

Mutation of G-protein γ subunit DEP1 increases planting density and resistance to sheath blight disease in rice.

One of the important goals of crop breeding is yield improvement. Among the yield indices, the tiller angle is tightly associated with enhancing photosynthetic efficiency and facilitating enhanced planting density (Sakamoto et al., 2006; Wang and Li, 2008). Rice plants with erect tillers, leaves, and panicles allow a high-density planting system for high yields but are more susceptible to the occurrence of sheath blight disease causing yield reduction.
Jing Miao Liu, Qiong Mei, Cai Yun Xue, Zi Yuan Wang, Dao Pin Li, Yong Xin Zhang, Yuan Hu Xuan

1004 related Products with: Mutation of G-protein γ subunit DEP1 increases planting density and resistance to sheath blight disease in rice.

1 mg100 100 1 mg100μg1mg100μg50101mg1mg1 mg

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#33098724   2020/10/24 To Up

Structural determinants for NF-Y subunit organization and NF-Y/DNA association in plants.

NF-Y transcription factor comprises three subunits; NF-YA, NF-YB, and NF-YC. NF-YB and NF-YC dimerize through their histone fold domain (HFD), which can bind DNA in a non-sequence-specific fashion while serving as a scaffold for NF-YA trimerization. Upon trimerization, NF-YA specifically recognizes the CCAAT box sequence on promoters and enhancers. In plants, each NF-Y subunit is encoded by several genes giving rise to hundreds of potential heterotrimeric combinations. In addition, plant NF-YBs and NF-YCs interact with other protein partners to recognize a plethora of genomic motifs, as the CCT protein family that binds CORE sites. The NF-Y subunit organization and its DNA-binding properties, together with the NF-Y HFD capacity to adapt different protein modules, represent plant-specific features that play a key role in development, growth and reproduction. Despite their relevance, these features are still poorly understood at the molecular level. Here, we present the structures of Arabidopsis and rice NF-YB/NF-YC dimers, and of an Arabidopsis NF-Y trimer in complex with the FT CCAAT box, together with biochemical data on NF-Y mutants. The dimeric structures identify the key residues for NF-Y HFD stabilization. The NF-Y/DNA structure and the mutation experiments shed light on HFD trimerization interface properties and the NF-YA sequence appetite for the bases flanking the CCAAT motif. These data explain the logic of plant NF-Y gene expansion: the trimerization adaptability and the flexible DNA-binding rules serve the scopes of accommodating the large number of NF-YAs, CCTs and possibly other NF-Y HFD binding partners and a diverse audience of genomic motifs.
Antonio Chaves-Sanjuan, Nerina Gnesutta, Andrea Gobbini, Damiano Martignago, Andrea Bernardini, Fabio Fornara, Roberto Mantovani, Marco Nardini

1633 related Products with: Structural determinants for NF-Y subunit organization and NF-Y/DNA association in plants.

20 100 μg2 mg 1 G0.1 mg1 mg100 100 ul100μg100 ug25 mg

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#33098696   2020/10/24 To Up

RLTPR Q575E: A novel recurrent gain-of-function mutation in patients with adult T-cell leukemia/lymphoma.

Adult T-cell leukemia/lymphoma (ATL) is an intractable T-cell malignancy caused by long-term infection with human T-cell leukemia virus type-1 (HTLV-1). While ATL pathogenesis has been associated with HTLV-1-derived oncogenic proteins, including Tax and HBZ, the contribution of genomic aberrations remains poorly defined.
Yuichiro Uchida, Makoto Yoshimitsu, Miho Hachiman, Shuichi Kusano, Naosuke Arima, Kodai Shima, Maiko Hayashida, Yuhei Kamada, Daisuke Nakamura, Akihiko Arai, Yuetsu Tanaka, Hiromitsu Hara, Kenji Ishitsuka

1340 related Products with: RLTPR Q575E: A novel recurrent gain-of-function mutation in patients with adult T-cell leukemia/lymphoma.

100ug Lyophilized18 kgs100ug Lyophilized25 ml.24 tests100ug Lyophilized2 Pieces/Box24 tests

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#33098688   2020/10/24 To Up

A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1.

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Xiping Chen, Olawale G Raimi, Andrew T Ferenbach, Daan M F van Aalten

1268 related Products with: A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1.

900 tests12 Pieces/Box

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#33098674   2020/10/24 To Up

The Impact of Vitamin D Status on Cardiometabolic Effects of Fenofibrate in Women with Atherogenic Dyslipidemia.

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Robert Krysiak, Karolina Kowalcze, Bogusław Okopień

2305 related Products with: The Impact of Vitamin D Status on Cardiometabolic Effects of Fenofibrate in Women with Atherogenic Dyslipidemia.

20 100 assays100ug

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