Search results for: Rabbit Anti-Human MPO Antibodies
#25949380 2009/08/24 To Up
MPO-ANCA crescentic glomerulonephritis complicated by membranous nephropathy: MPO demonstrated in epimembranous deposits.
An elderly woman presented with haematuria and proteinuria accompanied by elevated serum myeloperoxidase (MPO)-specific anti-neutrophil cytoplasmic antibodies (MPO-ANCA). A renal biopsy revealed mild mesangial proliferation with fibrocellular crescent formation and a membranous glomerular lesion. Immunofluorescence microscopy using FITC-labelled rabbit anti-human MPO antibodies revealed granular MPO deposition along the glomerular capillary walls (GCW) with a staining profile similar to that of glomerular IgG deposition. The one-year follow-up renal biopsy revealed minimal IgG and undetectable MPO deposition. Both MPO and MPO-ANCA might have been responsible for the IgG immune depositions along the GCW in this patient.Kei Matsumoto, Hirokazu Honda, Takanori Shibata, Daisuke Sanada, Yukihiro Wada, Eijin Ashikaga, Aki Kuroki, Kozo Kitazawa, Tadao Akizawa
2990 related Products with: MPO-ANCA crescentic glomerulonephritis complicated by membranous nephropathy: MPO demonstrated in epimembranous deposits.
100 μg100 μg0.1ml100ug Lyophilized200ul50100ug Lyophilized100ug LyophilizedRelated Pathways
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