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Search results for: Rectal

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#33096166   2020/10/20 To Up

Multivariate normal tissue complication probability models for rectal and bladder morbidity in prostate cancer patients treated with proton therapy.

Normal tissue complication probability (NTCP) models applied for model-based patient selection to proton therapy (PT) have usually been derived using dose/volume histogram (DVH) parameters from photon-based radiotherapy. This study aimed to derive PT-specific multivariate NTCP models that also accounted for the spatial dose distribution (rectum only) as well as non-dose/volume related factors.
Jesper Pedersen, Xiaoying Liang, Oscar Casares-Magaz, Curtis Bryant, Nancy Mendenhall, Zuofeng Li, Ludvig P Muren

1408 related Products with: Multivariate normal tissue complication probability models for rectal and bladder morbidity in prostate cancer patients treated with proton therapy.



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#33095858   2020/10/23 To Up

Growth performance and hematological changes of weaned beef calves diagnosed with respiratory disease using respiratory scoring and thoracic ultrasonography.

This study investigated (i) the effect of clinical bovine respiratory disease (BRD) and associated lung consolidations on growth performance and hematological profiles of recently weaned beef calves and (ii) the relationship between clinical respiratory signs and lung consolidation detected by thoracic ultrasonography (TUS). One hundred and fifty-three weaned beef calves (209 (SD; 35.8) days old and 306 (SD; 26.3) kg, at arrival) purchased and transported from auction markets were accommodated indoors in concrete slatted floor pens. Calves were weighed weekly from arrival until d 28 and on d 65 post-arrival. Assessment of BRD and blood sample collection for hematological profiles were performed on scheduled days (at arrival, on d 7, 14 and 28) and on other days upon BRD diagnosis. Animals were assessed for BRD using a total clinical respiratory score (CRS) of five clinical signs (rectal temperature, ear position, cough, nasal secretion and eye secretion with each ranging from normal (0) to abnormal (3)), and TUS scores (normal (0) to lung consolidation ≥ 1 cm 2 (2)). Based on CRS, 35% of calves were CRS+ (CRS ≥5) and 65% were CRS- (CRS <5). Although no lung consolidations (TUS-) were detected at arrival, 34% of calves developed lung consolidation (≥ 1 cm 2) (TUS+) during the first 28 d post-arrival. Only fever (>39.6 oC) and nasal discharge were weakly associated (r 0.19, P <0.05) with lung consolidation. On the day of BRD detection, neutrophil number and neutrophil:lymphocyte ratio was 58% and 73% greater, respectively, in BRD calves with lung consolidation compared to healthy calves. From d 0 to 65, calf ADG did not differ (P >0.05) between CRS+ and CRS- calves, but was 0.09 kg/d lower (P <0.05) for TUS+ compared to TUS- calves. Calves classified as BRD (CRS+TUS ≥5) with lung consolidation had lower (P <0.05) ADG from arrival until d 28 than healthy calves and BRD calves without lung consolidation (0.11 ± 0.10 vs. 0.53 ± 0.07 vs. 0.57 ± 0.10 kg/d, respectively); however, no differences in ADG were observed from d 0 to 65. Conventional methods to diagnose BRD failed to detect calves with lung lesions. Thoracic ultrasonography is a useful tool to detect lung lesions and its implementation in combination with CRS should provide a more accurate and early diagnosis of BRD, which is fundamental to successful treatment, animal welfare and growth performance.
Inmaculada Cuevas-Gómez, Mark McGee, Matthew McCabe, Paul Cormican, Edward O'Riordan, Tara McDaneld, Bernadette Earley

2640 related Products with: Growth performance and hematological changes of weaned beef calves diagnosed with respiratory disease using respiratory scoring and thoracic ultrasonography.

1 g96 wells (1 kit)100ug10 mg100 mg100ul200ul0.1 mg100 mg100.00 ul 25 MG200ug

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#33095857   2020/10/23 To Up

Obtaining nasal and rectal swabs from general practice patients to assess carriage of antibiotic resistant microorganisms: a feasibility study.

The aim of this study was to assess the feasibility of obtaining nasal and rectal swabs from general practice patients for measuring carriage of antibiotic resistant microorganisms in an area in Rotterdam (the Netherlands) with low socioeconomic status and a large immigrant population.
Maaike Honsbeek, Aimée Tjon-A-Tsien, Emina Omeragic, Ellen Stobberingh, Wilbert van Oorschot, Margreet Vos, Jan Hendrik Richardus, Hélène Voeten

1031 related Products with: Obtaining nasal and rectal swabs from general practice patients to assess carriage of antibiotic resistant microorganisms: a feasibility study.

1,000 tests100 μg100 g1 module100ug100 μg1 mg 25 G1 mg1 mL

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#33095692   2020/10/23 To Up

Hypofractionated Prostate Radiation Therapy: Adoption and Dosimetric Adherence Through Clinical Pathways in an Integrated Oncology Network.

Updates to consensus guidelines in October 2018 recommending moderately hypofractionated external beam radiotherapy (mHF-EBRT) in prostate cancer lagged several years after publication of evidence supporting its efficacy. In January 2018, we amended our prostate cancer clinical pathway (CP) to facilitate adoption of mHF-EBRT. Herein, we analyze patterns of care and changes in mHF-EBRT use after the CP modification.
Michael D Schad, Ankur K Patel, Diane C Ling, Ryan P Smith, Sushil Beriwal

1250 related Products with: Hypofractionated Prostate Radiation Therapy: Adoption and Dosimetric Adherence Through Clinical Pathways in an Integrated Oncology Network.



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#33095659   2020/10/23 To Up

Rectal spacer hydrogel in 1.5T MR-guided and daily adapted SBRT for prostate cancer: dosimetric analysis and preliminary patient-reported outcomes.

The main aim of the current analysis was to explore the hypothetical advantages using rectal spacer during 1.5T MR-guided and daily-adapted PC SBRT compared to a no-rectal spacer hydrogel cohort of patients.
Filippo Alongi, Michele Rigo, Vanessa Figlia, Francesco Cuccia, Niccolò Giaj-Levra, Luca Nicosia, Francesco Ricchetti, Claudio Vitale, Gianluisa Sicignano, Antonio De Simone, Stefania Naccarato, Ruggero Ruggieri, Rosario Mazzola

1193 related Products with: Rectal spacer hydrogel in 1.5T MR-guided and daily adapted SBRT for prostate cancer: dosimetric analysis and preliminary patient-reported outcomes.



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#33095361   2020/10/23 To Up

ASO Author Reflections: Local Excision Following Neoadjuvant Therapy for Rectal Cancer: A Compromise Between TME and Watch-and-Wait in Patients with Major Response.


Quoc Riccardo Bao, Giulia Capelli, Gaya Spolverato, Salvatore Pucciarelli

2880 related Products with: ASO Author Reflections: Local Excision Following Neoadjuvant Therapy for Rectal Cancer: A Compromise Between TME and Watch-and-Wait in Patients with Major Response.



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#33095327   2020/10/23 To Up

Delorme surgery for colonic mucosal prolapse after intersphincteric resection.

Mucosal prolapse at the site of anastomosis is a long-term complication unique to ISR. It reduces the QOL of patients due to a worsened anal function and local symptoms around the anus. We herein sought to assess the surgical outcomes after Delorme surgery for these patients.
Satoshi Narihiro, Naoko Miura, Yuji Nishizawa, Hiro Hasegawa, Koji Ikeda, Koichi Teramura, Yuichiro Tsukada, Takeshi Sasaki, Masaaki Ito

2723 related Products with: Delorme surgery for colonic mucosal prolapse after intersphincteric resection.

1 G100 TESTS500 ml2x96 well plate 1 G 5 G100 ug250 mg96 Tests

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#33095107   2020/10/23 To Up

Antibiotic Prophylaxis with Piperacillin-Tazobactam Reduces Post-Operative Infectious Complication after Pancreatic Surgery: An Interventional, Non-Randomized Study.

This study aimed to evaluate the effectiveness of piperacillin-tazobactam as antibiotic prophylaxis in patients affected by a peri-ampullary tumor submitted to pancreatic surgery. A prospective, non-randomized, non-blinded, interventional study was conducted from January 2015 to March 2018. Patients were screened pre-operatively for Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBL-PE). During the baseline period (January 2015-October 2016), surgical prophylaxis was performed with ampicillin-sulbactam. In the intervention phase (November 2016-March 2018), patients received piperacillin-tazobactam. Statistical analysis was performed by univariable and multivariable analysis with logistic regression models. Overall, 383 patients were included in the baseline period and 296 in the intervention period. The surveillance strategy identified 47 ESBL-PE carriers (14%) in the baseline phase and 29 (10%) in the intervention phase. In the baseline period, the patients had a higher rate of hospital-acquired infection (43% versus 33%; p = 0.004), superficial surgical site infection (SSI) (11% versus 2%; p < 0.001), and pneumonia (16% versus 9%; p = 0.006). After the logistic regression, the baseline group had an odds ratio to develop superficial SSI and pneumonia of 7.7 (95% confidence interval [CI] 3-20) and 1.8 (95% CI 1-3.3), respectively. The ESBL colonization increased the mortality rate significantly (8% versus 3%; p = 0.017). Adopting antibiotic prophylaxis based on piperacillin-tazobactam is associated with a reduction in post-operative SSI, particularly superficial-SSIs. Further randomized studies would be warranted to evaluate this antibiotic combination more extensively in preventive strategies.
Matteo De Pastena, Salvatore Paiella, Anna Maria Azzini, Amina Zaffagnini, Luigi Scarlini, Greta Montagnini, Martina Maruccio, Chiara Filippini, Francesco Romeo, Annarita Mazzariol, Giuliana Lo Cascio, Alda Bazaj, Erica Secchettin, Claudio Bassi, Roberto Salvia

2689 related Products with: Antibiotic Prophylaxis with Piperacillin-Tazobactam Reduces Post-Operative Infectious Complication after Pancreatic Surgery: An Interventional, Non-Randomized Study.

100100100100500 tests100 100 1.00 kit500 tests1-99 mg/ml/ea price x 2500 tests

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#33094828   2020/10/22 To Up

Comparison of conventional and modified endoscopic mucosal resection methods for the treatment of rectal neuroendocrine tumors.

Small rectal neuroendocrine tumors (NETs) confined to the submucosa are endoscopically resectable. Because most rectal NETs are submucosal tumors, conventional endoscopic mucosal resection (cEMR) may not result in a complete resection. This study investigated whether modified EMRs, namely endoscopic submucosal resection with ligation (ESMR-L), EMR with precutting (EMR-P), and strip biopsy are superior to cEMR for achieving histologically complete resection (HCR) of rectal NETs.
Hee Sung Lee, Hee Seok Moon, In Sun Kwon, Jae Ho Park, Ju Seok Kim, Sun Hyung Kang, Eaum Seok Lee, Seok Hyun Kim, Jae Kyu Sung, Byung Seok Lee, Hyun Yong Jeong

1289 related Products with: Comparison of conventional and modified endoscopic mucosal resection methods for the treatment of rectal neuroendocrine tumors.

200ul 5 G11 mg1 ml250 mg100tests25 mg1mg 1 G1 ml

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