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Search results for: Serum

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#32770852   2020/08/08 To Up

Slot blotting and flow cytometry: two efficient assays for platelet antibody screening among patients with platelet refractoriness.

Frequent platelet transfusion may lead to the formation of alloantibodies and immune-mediated platelet destruction. Currently, identifying economic and effective screening methods is necessary for the management of platelet transfusion while different tests were recommended. The present study aims to challenge the performance of slot blotting (SB) and flow cytometry (FC) assays in detecting immune platelet refractoriness.
Zahra Ameri, Reza Vahidi, Morteza Khaleghi, Tania Dehesh, Amir Sheikhbardsiri, Alireza Farsinejad

2228 related Products with: Slot blotting and flow cytometry: two efficient assays for platelet antibody screening among patients with platelet refractoriness.

100ul1 kit25 µg100μg100ug Lyophilized100ug Lyophilized100ug Lyophilized100ug Lyophilized100ug Lyophilized100ug Lyophilized4 Sample Kit100ul

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#32770795   2020/08/08 To Up

Inflammatory Effects of Thickened Water on the Lungs in a Murine Model of Recurrent Aspiration.

Liquid thickeners are commonly recommended in individuals with dysphagia and recurrent aspiration as a strategy for pneumonia prevention. The goal of this study was to examine the effects of small amounts of aspirated liquid thickener on the lungs.
Nogah Nativ-Zeltzer, Rumi Ueha, Yuval Nachalon, Betty Ma, Gabrielle Pastenkos, Clay Swackhamer, Gail M Bornhorst, Maureen A Lefton-Greif, Johnathon D Anderson, Peter C Belafsky

1981 related Products with: Inflammatory Effects of Thickened Water on the Lungs in a Murine Model of Recurrent Aspiration.

0.1 mg50μl5ug100ug18 kgs5ug15ug

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#32770776   2020/08/08 To Up

Competing-risks model for prediction of small-for-gestational-age neonates from maternal characteristics and serum pregnancy-associated plasma protein-A at 11-13 weeks' gestation.

To develop a continuous likelihood model for the pregnancy associated plasma protein - A (PAPP-A), in the context of a new competing risks model for small for gestational age (SGA) neonates. To compare the predictive performance of the new model for SGA to that of previous methods.
I Papastefanou, D Wright, A Syngelaki, M Lolos, K Anampousi, K H Nicolaides

2806 related Products with: Competing-risks model for prediction of small-for-gestational-age neonates from maternal characteristics and serum pregnancy-associated plasma protein-A at 11-13 weeks' gestation.

96T96T96T96T1 kit96T96T10reactions 1 kit(96 Wells)0.1 mg1 kit(96 Wells)

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#32770725   2020/08/08 To Up

Differences in HDL-Cholesterol Efflux Capacity Between Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis.

Cholesterol efflux capacity (CEC) is the ability of high-density lipoprotein (HDL)-cholesterol to accept cholesterol from macrophages. Lipid profiles and CEC appear to be altered in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) due to disease activity and inflammation. CEC has been linked to cardiovascular events in the general population and to subclinical atherosclerosis in SLE and RA patients. The aim of this study was to establish whether CEC varies between patients with SLE and those with RA.
Juan C Quevedo-Abeledo, Hiurma Sánchez-Pérez, Beatriz Tejera-Segura, Laura de Armas-Rillo, Estefanía Armas-González, José David Machado, Miguel A González-Gay, Federico Díaz-González, Iván Ferraz-Amaro

1827 related Products with: Differences in HDL-Cholesterol Efflux Capacity Between Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis.

100ug Lyophilized100ug Lyophilized100ug Lyophilized 5 G100ug100ug Lyophilized1 Set1 mg1 Set

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#32770702   2020/08/08 To Up

The role of alternative sugars on endurance capacity in balb/c mice.

Alternative sugars containing isomaltulose were investigated to confirm the hypothesis that isomaltulose ingestion affects endurance capacity due to slow rates of hydrolysis and absorption rate at the intestine. A swimming time of the control group tends to decrease, but the group administrated with low glycemic index (GI) sweeteners tend to increase gradually. Fructo-oligosaccharide (FOS) and inverted sugar (IS), contained isomaltulose, groups showed a significant difference of change in blood glucose and lactic acid level than control group (p < .05). Serum creatine phosphokinase (CPK) and serum lactate dehydrogenases (LDH) of PAL100 were significantly lower than that of the control group (p < .05). IS showed a significant difference in glutathione peroxidase (GSH-Px) compared to Con and PAL20 (20% isomaltulose) group (p < .05). Consuming FOS seems to increase an endurance capacity since fructose and FOS based in isomaltulose contained syrup showed low absorption rate and GI level. PRACTICAL APPLICATIONS: Sugar is a major energy source for exercise, but it causes excessive intake because of the short duration of sweetness, which causes diseases such as obesity, diabetes, and skin aging. An alternative sugar complex containing isomatulose was found to be a sugar substitute for athletic performance. Athletic performance is not just for athletes or active people. In general, elderly people with low muscle mass have low mobility. Alternative sugars can be a good source of supplements to help them perform smoothly with less intake. Therefore, an endurance test with alternative sugars is and important study for energy supplements industry.
Singeun Kim, Kyungae Jo, Nari Kim, Ki-Bae Hong, Hyung Joo Suh

2949 related Products with: The role of alternative sugars on endurance capacity in balb/c mice.

1mg1 100 UG100ug100 µl

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#32770697   2020/08/08 To Up

Curcumin and Baicalin ameliorate ethanol-induced liver oxidative damage via the Nrf2/HO-1 pathway.

One of the key mechanisms of alcoholic liver disease is oxidative stress. Both Curcumin and Baicalin exert antioxidant effects, but the mechanism of their combined effects of ethanol-induced liver injury is still unclear. This study was conducted to evaluate the dual antioxidant activity of Curcumin combined with Baicalin against ethanol-induced liver injury in rats. Rats were divided into five groups, a control, ethanol, ethanol + Curcumin (50 mg/kg), ethanol + Baicalin (50 mg/kg), and ethanol + Curcumin +Baicalin group with ten rats per group. The effects of ethanol on liver enzymes, oxidative stress indicators and the levels of Nrf2/HO-1 pathway related proteins and mRNA were observed along with liver histopathology in rats. Our results found that the serum ALT and AKP levels were increased in ethanol-treated rats, which also showed a rising trend of 8-OHdG and LPO levels while hydroxyl radical scavenging ability, T-AOC, and the activities of SOD and GSH-Px were decreased in liver. The mRNA levels of Nrf2 and HO-1, the ratio of p-Nrf2/Nrf2, the protein level of HO-1 were decreased while NQO1 mRNA level, Nrf2, p-Nrf2, and NQO1 protein levels were increased in ethanol-treated rats. Combination treatment of Curcumin and Baicalin significantly reversed the ethanol-induced liver oxidative damage and further activate the Nrf2/HO-1 pathway, which was more effective than each drug alone. In conclusion, evidence has shown for the first time in this study that Curcumin combined with Baicalin ameliorated ethanol-induced liver oxidative damage in rats and revealed liver-protection. PRACTICAL APPLICATIONS: Many drugs for treating alcoholic liver disease are available commercially, but some adverse effects they have may cause secondary damage to the liver. At present, the combined treatment of different natural phytochemicals has attracted special attention in modern medicine. Curcumin, a kind of phytochemicals, is extracted from turmeric rhizome. Baicalin is one of the major active components of Scutellaria Baicalensis. The current research is to explore the antioxidant effect of Curcumin and Baicalin in ethanol-induced liver injury in rats. Our research proves that Curcumin combined with Baicalin on ethanol-induced liver oxidative damage is superior to single drug treatment. Therefore, the combination of Curcumin and Baicalin may provide a more prospective natural remedy to combat ethanol-induced liver injury.
Xiaoxia Wang, Xuhong Chang, Haibing Zhan, Qiong Zhang, Chengyun Li, Qing Gao, Mengmeng Yang, Zhen Luo, Sheng Li, Yingbiao Sun

1672 related Products with: Curcumin and Baicalin ameliorate ethanol-induced liver oxidative damage via the Nrf2/HO-1 pathway.

1000pcs100ug1000 tests100 mg10001000pcs100ug100ug100ug/vial100ug/vial10μg/vial100μg/vial

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#32770634   2020/08/07 To Up

A Serum Protein Signature is associated with Rheumatoid Arthritis development.

The pathophysiologic events that precede the onset of Rheumatoid Arthritis (RA) remain incompletely understood. We aimed to identify changes in the serum proteome that precede RA and provide new insights into the pathogenic mechanisms that lead to its development.
Liam J O'Neil, Victor Spicer, Irene Smolik, Xiaobo Meng, Rishi R Goel, Vidyanand Anaparti, John Wilkins, Hani S El-Gabalawy

1164 related Products with: A Serum Protein Signature is associated with Rheumatoid Arthritis development.

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#32770633   2020/08/08 To Up

Robotic Assisted Kidney Transplantation: Update from the ERUS series.

To report the results of the robotic assisted kidney transplantation experience performed in 10 European centers members of the ERUS-RAKT group.
Mireia Musquera, Lluis Peri, Tarek Ajami, Alberto Breda, Riccardo Campi, Volkan Tugcu, Karel Decaestecker, Michael Stockle, Paolo Fornara, Nicolas Doumerc, Frances Vigues, Ravi Barod, Liesbeth Desender, Angelo Territo, Sergio Serni, GrazianoVignolini, Selçuk Sahin, Philipe Zeuschner, Neal Banga, Antonio Alcaraz

1790 related Products with: Robotic Assisted Kidney Transplantation: Update from the ERUS series.

1 100ul500 Units

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#32770525   2020/08/08 To Up

Overexpression of reactive oxygen species modulator 1 is associated with advanced grades of bladder cancer.

Reactive Oxygen Species Modulator 1 (ROMO1) plays a pivotal role in the regulation of mitochondrial structure integrity, and the production of reactive oxygen species (ROS). Increased ROMO1 expression was reported in various cancer cell lines; however, the possible association between ROMO1 expression and bladder cancer was not well studied. The present study aimed to investigate the rate of ROMO1 expression and the correlation of oxidative stress with the development of bladder cancer. In this study, a total of 35 cancerous and healthy adjacent tissues were examined using quantitative real-time polymerase chain reaction (qRT-PCR) to analyze the gene expression of ROMO1. Also, we evaluated the serum level of ROMO1 and Total Antioxidant Capacity (TAC), as well as Total Oxidant Status (TOS) in patients with bladder cancer along with age- and sex-matched healthy individuals. The ROMO1 gene was significantly higher in cancerous tissues than that of adjacent healthy tissues. Also, the serum levels of ROMO1, TAC, TOS, and Oxidative Stress Index (OSI) were increased in patients with bladder cancer compared with healthy subjects. It can be concluded that the overexpression of the ROMO1 gene is associated with advanced grades of bladder cancer as well as an increase in oxidative stress conditions. Our findings also suggest that the serum level of ROMO1 might be a promising tumor marker for bladder cancer.
Hadi Ghasemi, Mohammad Amin Amini, Atefeh Pegah, Ebrahim Azizi, Heidar Tayebinia, Shima Khanverdilou, Seyed Habibollah Mousavibahar, Aida Alizamir

1227 related Products with: Overexpression of reactive oxygen species modulator 1 is associated with advanced grades of bladder cancer.

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#32770419   2020/08/08 To Up

A higher level of serum furin indicates a higher risk of microalbuminuria: results from a longitudinal study in Chinese adults.

Furin, a key enzyme of natriuretic peptide system, has been suggested to play a role in microalbuminuria, but the association between furin and microalbuminuria has been scarcely studied.
Liyun Ren, Yan Chen, Qiu Zhang, Mingzhi Zhang, Jia Yu, Yan He, Hao Peng

2460 related Products with: A higher level of serum furin indicates a higher risk of microalbuminuria: results from a longitudinal study in Chinese adults.

96T96 tests50 ul100 µg100 μg100 assays

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